AutismKB 2.0

Annotation Detail for PXDN


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Basic Information Top
Gene Symbol:PXDN ( D2S448,D2S448E,KIAA0230,MG50,PRG2,PXN,VPO )
Gene Full Name: peroxidasin homolog (Drosophila)
Band: 2p25.3
Quick LinksEntrez ID:7837; OMIM: 605158; Uniprot ID:PXDN_HUMAN; ENSEMBL ID: ENSG00000130508; HGNC ID: 14966
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body40 / 70761565
blastocyst8 / 62319128
fetus126 / 564012223
neonate10 / 31097321
infant0 / 236200 
juvenile0 / 555560 
adult216 / 1939121111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor7 / 9417874
cervical tumor17 / 34366494
chondrosarcoma34 / 82823410
colorectal tumor18 / 114246157
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor55 / 263845208
glioma12 / 106883112
head and neck tumor5 / 13630236
kidney tumor8 / 68959116
leukemia18 / 95842187
liver tumor7 / 9635972
lung tumor5 / 10312748
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal365 / 3360307108
ovarian tumor19 / 76682247
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor3 / 12494924
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone12 / 71655167
bone marrow12 / 48801245
brain40 / 110098936
cervix17 / 48171352
connective tissue32 / 149255214
ear3 / 16212185
embryonic tissue61 / 215722282
esophagus0 / 202090 
eye22 / 211054104
heart33 / 89626368
intestine30 / 234472127
kidney21 / 21177799
larynx2 / 2414582
liver12 / 20774357
lung67 / 336974198
lymph0 / 442700 
lymph node21 / 91610229
mammary gland17 / 153271110
mouth3 / 6705244
muscle9 / 10771583
nerve0 / 157680 
ovary19 / 102051186
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta18 / 28082564
prostate5 / 18934526
salivary gland0 / 201550 
skin28 / 210574132
spleen5 / 5395292
stomach5 / 9661951
testis37 / 330442111
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord10 / 13680730
uterus25 / 232878107
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212013_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.7
Adipocyte281.2
AdrenalCortex4.25
Adrenalgland3.25
Amygdala3.95
Appendix4.3
AtrioventricularNode2.95
BDCA4+_DentriticCells4.3
Bonemarrow3.85
BronchialEpithelialCells60.45
CD105+_Endothelial4.4
CD14+_Monocytes4.2
CD19+_BCells(neg._sel.)4.1
CD33+_Myeloid4.9
CD34+8.3
CD4+_Tcells4.15
CD56+_NKCells4.5
CD71+_EarlyErythroid3.55
CD8+_Tcells3.7
CardiacMyocytes295.05
Caudatenucleus3.5
Cerebellum3.15
CerebellumPeduncles4.4
CiliaryGanglion2.75
CingulateCortex4.05
Colorectaladenocarcinoma3.8
DorsalRootGanglion3.05
FetalThyroid9.05
Fetalbrain4.6
Fetalliver3.4
Fetallung11.9
GlobusPallidus2.8
Heart5.2
Hypothalamus4.4
Kidney3.15
Leukemia_chronicMyelogenousK-5623.4
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)3.2
Liver5.2
Lung4.45
Lymphnode3.45
Lymphoma_burkitts(Daudi)4.95
Lymphoma_burkitts(Raji)5.4
MedullaOblongata3.8
OccipitalLobe3.5
OlfactoryBulb3.1
Ovary3.1
Pancreas3.4
PancreaticIslet4.25
ParietalLobe4.45
Pituitary4.65
Placenta42.15
Pons3.75
PrefrontalCortex4.8
Prostate6.6
Salivarygland3.1
SkeletalMuscle4.75
Skin3.1
SmoothMuscle1759.35
Spinalcord4.2
SubthalamicNucleus3.55
SuperiorCervicalGanglion4.5
TemporalLobe3.55
Testis3.5
TestisGermCell3.9
TestisIntersitial3.35
TestisLeydigCell3.85
TestisSeminiferousTubule3.7
Thalamus3.95
Thymus3.1
Thyroid4.75
Tongue3.85
Tonsil3.85
Trachea3.85
TrigeminalGanglion4.15
Uterus7.5
UterusCorpus32.4
WholeBlood4.25
Wholebrain3.15
colon4.8
pineal_day4.8
pineal_night4.68
retina6.75
small_intestine14.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P257144
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.54 ± 0.45
Basal Forebrain6.64 ± 0.52
Basal Part of Pons5.45 ± 0.32
Cerebellar Cortex5.7 ± 0.51
Cerebellar Nuclei6.3 ± 0.3
Claustrum6.52 ± 0.48
Epithalamus5.94 ± 0.62
Frontal Lobe6.13 ± 0.56
Globus Pallidus7.89 ± 0.62
Hypothalamus6.48 ± 0.6
Insula6.6 ± 0.29
Limbic Lobe6.65 ± 0.85
Mesencephalon6.77 ± 0.6
Myelencephalon6.48 ± 0.74
Occipital Lobe7.31 ± 0.91
Parietal Lobe6.47 ± 0.52
Pontine Tegmentum6.74 ± 0.4
Striatum6.65 ± 0.56
Subthalamus5.92 ± 1.16
Temporal Lobe6.53 ± 0.52
Thalamus6.4 ± 0.46
White Matter6.65 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PxdnCBCerebellum21.18
29.8
PxdnCTXCerebral cortex70.23
51.61
PxdnHIPHippocampal region49.94
66.95
PxdnHPFHippocampal formation63.82
72.07
PxdnHYHypothalamus6.48
4.96
PxdnLSXLateral septal complex6.78
4.17
PxdnMBMidbrain6.21
5.73
PxdnMYMedulla14.44
15.21
PxdnOLFOlfactory bulb50.5
40.3
PxdnPPons11.45
11.15
PxdnPALPallidum11.23
9.73
PxdnRHPRetrohippocampal region89.73
81.74
PxdnsAMYStriatum-like amygdalar nuclei32.99
26.04
PxdnSTRStriatum43.94
30.37
PxdnSTRdStriatum dorsal region52.91
35.94
PxdnSTRvStriatum ventral region35.43
25.15
PxdnTHThalamus12.82
12.84
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp01434386 21 571 591 FHISPEGFLTINDVGPADAGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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