AutismKB 2.0

Annotation Detail for MOGS


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Basic Information Top
Gene Symbol:MOGS ( CDG2B,GCS1 )
Gene Full Name: mannosyl-oligosaccharide glucosidase
Band: 2p13.1
Quick LinksEntrez ID:7841; OMIM: 601336; Uniprot ID:MOGS_HUMAN; ENSEMBL ID: ENSG00000115275; HGNC ID: 24862
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst8 / 62319128
fetus29 / 56401251
neonate0 / 310970 
infant0 / 236200 
juvenile6 / 55556107
adult139 / 193912171
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma3 / 17475171
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma9 / 82823108
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor12 / 119369100
germ cell tumor41 / 263845155
glioma6 / 10688356
head and neck tumor6 / 13630244
kidney tumor5 / 6895972
leukemia8 / 9584283
liver tumor5 / 9635951
lung tumor9 / 10312787
lymphoma4 / 7175555
non-neoplasia3 / 9725030
normal166 / 336030749
ovarian tumor20 / 76682260
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer6 / 10268058
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites2 / 4001549
bladder1 / 2975733
blood15 / 123478121
bone5 / 7165569
bone marrow2 / 4880140
brain42 / 110098938
cervix5 / 48171103
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus0 / 202090 
eye8 / 21105437
heart2 / 8962622
intestine25 / 234472106
kidney11 / 21177751
larynx0 / 241450 
liver8 / 20774338
lung29 / 33697486
lymph1 / 4427022
lymph node7 / 9161076
mammary gland4 / 15327126
mouth5 / 6705274
muscle1 / 1077159
nerve0 / 157680 
ovary27 / 102051264
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta21 / 28082574
prostate16 / 18934584
salivary gland0 / 201550 
skin9 / 21057442
spleen3 / 5395255
stomach5 / 9661951
testis37 / 330442111
thymus8 / 8113198
thyroid4 / 4747384
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus15 / 23287864
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210627_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.4
Adipocyte4.4
AdrenalCortex4.6
Adrenalgland3.8
Amygdala4.4
Appendix4.4
AtrioventricularNode3.5
BDCA4+_DentriticCells6.2
Bonemarrow4.7
BronchialEpithelialCells4.45
CD105+_Endothelial4.5
CD14+_Monocytes5.4
CD19+_BCells(neg._sel.)5.15
CD33+_Myeloid5.8
CD34+5.75
CD4+_Tcells7.5
CD56+_NKCells6.95
CD71+_EarlyErythroid5.3
CD8+_Tcells6.75
CardiacMyocytes5.5
Caudatenucleus4
Cerebellum3.65
CerebellumPeduncles5
CiliaryGanglion3.35
CingulateCortex4.55
Colorectaladenocarcinoma8.3
DorsalRootGanglion3.35
FetalThyroid4.9
Fetalbrain4.4
Fetalliver3.9
Fetallung3.75
GlobusPallidus3.25
Heart5.7
Hypothalamus4.75
Kidney3.7
Leukemia_chronicMyelogenousK-5624
Leukemia_promyelocytic-HL-603.95
Leukemialymphoblastic(MOLT-4)3.65
Liver6.15
Lung5
Lymphnode4.3
Lymphoma_burkitts(Daudi)6.65
Lymphoma_burkitts(Raji)6.25
MedullaOblongata3.95
OccipitalLobe4
OlfactoryBulb3.55
Ovary2.95
Pancreas3.65
PancreaticIslet4.85
ParietalLobe4.65
Pituitary5.25
Placenta13.6
Pons4.2
PrefrontalCortex5.45
Prostate5.65
Salivarygland3.75
SkeletalMuscle5
Skin3.6
SmoothMuscle5.95
Spinalcord4.7
SubthalamicNucleus4
SuperiorCervicalGanglion5
TemporalLobe4.05
Testis3.8
TestisGermCell3.7
TestisIntersitial3.7
TestisLeydigCell4.4
TestisSeminiferousTubule3.85
Thalamus4.55
Thymus3.5
Thyroid5.65
Tongue4.3
Tonsil4.35
Trachea3.7
TrigeminalGanglion4.3
Uterus3.6
UterusCorpus3.95
WholeBlood4.85
Wholebrain3.6
colon4.5
pineal_day5.58
pineal_night5.44
retina5.4
small_intestine4.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P108662
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.88 ± 0.44
Basal Forebrain9.66 ± 0.24
Basal Part of Pons9.85 ± 0.29
Cerebellar Cortex9.91 ± 0.28
Cerebellar Nuclei9.8 ± 0.29
Claustrum9.92 ± 0.39
Epithalamus9.33 ± 0.36
Frontal Lobe9.69 ± 0.28
Globus Pallidus9.47 ± 0.24
Hypothalamus9.63 ± 0.21
Insula9.69 ± 0.31
Limbic Lobe9.71 ± 0.33
Mesencephalon9.73 ± 0.3
Myelencephalon9.71 ± 0.35
Occipital Lobe9.74 ± 0.23
Parietal Lobe9.64 ± 0.27
Pontine Tegmentum9.57 ± 0.28
Striatum9.51 ± 0.23
Subthalamus9.66 ± 0.23
Temporal Lobe9.7 ± 0.3
Thalamus9.7 ± 0.3
White Matter9.74 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gcs1CBCerebellum20.56
28.33
Gcs1CTXCerebral cortex36.64
25.98
Gcs1HIPHippocampal region22.76
22.55
Gcs1HPFHippocampal formation23.13
20.42
Gcs1HYHypothalamus16.43
12.21
Gcs1LSXLateral septal complex11.13
7.56
Gcs1MBMidbrain23.2
21.39
Gcs1MYMedulla27.26
31.46
Gcs1OLFOlfactory bulb31.45
23.32
Gcs1PPons25.17
27.15
Gcs1PALPallidum17.48
15.01
Gcs1RHPRetrohippocampal region24.77
18.1
Gcs1sAMYStriatum-like amygdalar nuclei17.81
12.9
Gcs1STRStriatum13.18
10.02
Gcs1STRdStriatum dorsal region12.07
10.3
Gcs1STRvStriatum ventral region15.4
9.59
Gcs1THThalamus25
19.66
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MOGS_HUMAN_159 9 159 167 QHIQDGALR PRIDE
MOGS_HUMAN_506 29 506 534 AVHANPPTLLLPVAHMLEVGDPDDLAFLR PRIDE
MOGS_HUMAN_709 12 709 720 LGPLLDILADSR PRIDE
PAp00042095 22 679 700 PQPQLQYVDALGYVSLFPLLLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018