AutismKB 2.0

Annotation Detail for IL1R2


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Basic Information Top
Gene Symbol:IL1R2 ( CD121b,IL1RB,MGC47725 )
Gene Full Name: interleukin 1 receptor, type II
Band: 2q11.2
Quick LinksEntrez ID:7850; OMIM: 147811; Uniprot ID:IL1R2_HUMAN; ENSEMBL ID: ENSG00000115590; HGNC ID: 5994
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor6 / 13630244
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal44 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood5 / 12347840
bone2 / 7165527
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine8 / 23447234
kidney5 / 21177723
larynx5 / 24145207
liver2 / 2077439
lung4 / 33697411
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth3 / 6705244
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta8 / 28082528
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach4 / 9661941
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211372_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.65
Adipocyte4.55
AdrenalCortex4.95
Adrenalgland3.9
Amygdala4.7
Appendix4.55
AtrioventricularNode3.5
BDCA4+_DentriticCells5.1
Bonemarrow116.5
BronchialEpithelialCells4.55
CD105+_Endothelial4.5
CD14+_Monocytes5.3
CD19+_BCells(neg._sel.)4.85
CD33+_Myeloid5.9
CD34+5.7
CD4+_Tcells4.8
CD56+_NKCells5.4
CD71+_EarlyErythroid4.25
CD8+_Tcells4.3
CardiacMyocytes5.85
Caudatenucleus4.15
Cerebellum3.75
CerebellumPeduncles5.45
CiliaryGanglion3.35
CingulateCortex4.7
Colorectaladenocarcinoma4.55
DorsalRootGanglion3.6
FetalThyroid4.4
Fetalbrain4.5
Fetalliver3.9
Fetallung15.95
GlobusPallidus3.35
Heart6.3
Hypothalamus5
Kidney5.2
Leukemia_chronicMyelogenousK-5624.1
Leukemia_promyelocytic-HL-604.7
Leukemialymphoblastic(MOLT-4)3.6
Liver8.65
Lung5
Lymphnode3.95
Lymphoma_burkitts(Daudi)5.8
Lymphoma_burkitts(Raji)50.6
MedullaOblongata4.2
OccipitalLobe4.05
OlfactoryBulb3.55
Ovary3.45
Pancreas3.85
PancreaticIslet4.85
ParietalLobe4.9
Pituitary5.35
Placenta15.25
Pons4.5
PrefrontalCortex5.6
Prostate5.3
Salivarygland3.6
SkeletalMuscle5.7
Skin3.8
SmoothMuscle5.15
Spinalcord4.8
SubthalamicNucleus4.2
SuperiorCervicalGanglion5.1
TemporalLobe4.5
Testis3.9
TestisGermCell3.8
TestisIntersitial3.8
TestisLeydigCell4.55
TestisSeminiferousTubule3.9
Thalamus4.7
Thymus3.6
Thyroid5.65
Tongue5.3
Tonsil18.75
Trachea4.35
TrigeminalGanglion4.8
Uterus3.7
UterusCorpus4.2
WholeBlood243.7
Wholebrain3.75
colon19.3
pineal_day5.6
pineal_night5.48
retina5.5
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P63019
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.3 ± 1.12
Basal Forebrain1.82 ± 0.2
Basal Part of Pons1.95 ± 0.62
Cerebellar Cortex1.76 ± 0.72
Cerebellar Nuclei2.13 ± 0.71
Claustrum2.64 ± 1.14
Epithalamus1.54 ± 0.88
Frontal Lobe1.61 ± 0.56
Globus Pallidus2.43 ± 0.51
Hypothalamus1.87 ± 0.59
Insula1.92 ± 0.78
Limbic Lobe1.84 ± 0.66
Mesencephalon2.02 ± 0.72
Myelencephalon1.9 ± 0.71
Occipital Lobe2.04 ± 0.73
Parietal Lobe1.85 ± 0.76
Pontine Tegmentum1.74 ± 0.71
Striatum1.96 ± 0.61
Subthalamus1.93 ± 0.65
Temporal Lobe1.77 ± 0.71
Thalamus1.8 ± 0.59
White Matter2.34 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Il1r2CBCerebellum0.97
2.71
Il1r2CTXCerebral cortex1.11
1.11
Il1r2HIPHippocampal region1.56
1.36
Il1r2HPFHippocampal formation1.13
1.07
Il1r2HYHypothalamus0.43
0.38
Il1r2LSXLateral septal complex0.15
0.08
Il1r2MBMidbrain0.37
0.78
Il1r2MYMedulla0.32
0.9
Il1r2OLFOlfactory bulb1.26
1.32
Il1r2PPons0.71
1.49
Il1r2PALPallidum0.03
0.04
Il1r2RHPRetrohippocampal region0.36
0.68
Il1r2sAMYStriatum-like amygdalar nuclei0.73
0.66
Il1r2STRStriatum0.12
0.12
Il1r2STRdStriatum dorsal region0.01
0.01
Il1r2STRvStriatum ventral region0.05
0.12
Il1r2THThalamus0.32
0.26
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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