AutismKB 2.0

Annotation Detail for BRPF1


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Basic Information Top
Gene Symbol:BRPF1 ( BR140 )
Gene Full Name: bromodomain and PHD finger containing, 1
Band: 3p25.3
Quick LinksEntrez ID:7862; OMIM: 602410; Uniprot ID:BRPF1_HUMAN; ENSEMBL ID: ENSG00000156983; HGNC ID: 14255
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult58 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor8 / 34366232
chondrosarcoma4 / 8282348
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor17 / 26384564
glioma3 / 10688328
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal63 / 336030718
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer5 / 10268048
retinoblastoma2 / 4635643
skin tumor12 / 12494996
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone1 / 7165513
bone marrow1 / 4880120
brain15 / 110098913
cervix8 / 48171166
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye7 / 21105433
heart1 / 8962611
intestine7 / 23447229
kidney0 / 2117770 
larynx1 / 2414541
liver2 / 2077439
lung14 / 33697441
lymph0 / 442700 
lymph node6 / 9161065
mammary gland4 / 15327126
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate7 / 18934536
salivary gland0 / 201550 
skin14 / 21057466
spleen1 / 5395218
stomach1 / 9661910
testis9 / 33044227
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204481_at
Cell line Expression level Expression bar
721_B_lymphoblasts17.75
Adipocyte9.25
AdrenalCortex10.45
Adrenalgland8.15
Amygdala9.9
Appendix10.15
AtrioventricularNode7.7
BDCA4+_DentriticCells37.55
Bonemarrow9.9
BronchialEpithelialCells9.2
CD105+_Endothelial13.75
CD14+_Monocytes27.8
CD19+_BCells(neg._sel.)17.95
CD33+_Myeloid20.2
CD34+19.45
CD4+_Tcells33.8
CD56+_NKCells19.9
CD71+_EarlyErythroid14
CD8+_Tcells21.6
CardiacMyocytes12.3
Caudatenucleus8.5
Cerebellum10.55
CerebellumPeduncles21.05
CiliaryGanglion6.95
CingulateCortex10.15
Colorectaladenocarcinoma8.2
DorsalRootGanglion7.5
FetalThyroid9.45
Fetalbrain9.45
Fetalliver8.7
Fetallung8.2
GlobusPallidus7
Heart17.1
Hypothalamus10.05
Kidney7.95
Leukemia_chronicMyelogenousK-5629.05
Leukemia_promyelocytic-HL-608.45
Leukemialymphoblastic(MOLT-4)13.1
Liver13.15
Lung19.05
Lymphnode8.65
Lymphoma_burkitts(Daudi)12.65
Lymphoma_burkitts(Raji)13.6
MedullaOblongata9
OccipitalLobe8.15
OlfactoryBulb7.85
Ovary6.55
Pancreas6.45
PancreaticIslet10.4
ParietalLobe10.2
Pituitary11.45
Placenta15.6
Pons9
PrefrontalCortex12.1
Prostate13.45
Salivarygland11.1
SkeletalMuscle11.35
Skin7.35
SmoothMuscle10.45
Spinalcord10.3
SubthalamicNucleus8.9
SuperiorCervicalGanglion11.45
TemporalLobe8.85
Testis33.45
TestisGermCell12.3
TestisIntersitial20.65
TestisLeydigCell16.65
TestisSeminiferousTubule29.2
Thalamus9.05
Thymus30.95
Thyroid12.85
Tongue9.45
Tonsil9.65
Trachea8.35
TrigeminalGanglion9.75
Uterus8.3
UterusCorpus8.95
WholeBlood19.55
Wholebrain8.6
colon9.55
pineal_day12.88
pineal_night11.98
retina14.9
small_intestine9.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_799_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.2 ± 0.59
Basal Forebrain3.68 ± 0.55
Basal Part of Pons4.66 ± 0.57
Cerebellar Cortex4.39 ± 0.61
Cerebellar Nuclei3.99 ± 0.5
Claustrum3.32 ± 0.78
Epithalamus4.44 ± 1.34
Frontal Lobe4.36 ± 0.55
Globus Pallidus3.63 ± 0.63
Hypothalamus4.46 ± 0.56
Insula4.46 ± 0.42
Limbic Lobe4.22 ± 0.6
Mesencephalon4.14 ± 0.63
Myelencephalon4.13 ± 0.59
Occipital Lobe3.76 ± 0.7
Parietal Lobe4.12 ± 0.51
Pontine Tegmentum3.97 ± 0.7
Striatum3.25 ± 0.55
Subthalamus4.19 ± 0.42
Temporal Lobe4.41 ± 0.48
Thalamus4.06 ± 0.55
White Matter3.83 ± 1.03
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Brpf1CBCerebellum55.82
67.47
Brpf1CTXCerebral cortex19.99
13.35
Brpf1HIPHippocampal region24.05
30.39
Brpf1HPFHippocampal formation21.06
22.24
Brpf1HYHypothalamus1.47
1
Brpf1LSXLateral septal complex1.36
1.15
Brpf1MBMidbrain5.07
4.2
Brpf1MYMedulla10.66
10.9
Brpf1OLFOlfactory bulb28.38
22.42
Brpf1PPons6.94
7.07
Brpf1PALPallidum1.48
1.13
Brpf1RHPRetrohippocampal region17.39
13.51
Brpf1sAMYStriatum-like amygdalar nuclei3.41
3.41
Brpf1STRStriatum5.35
4.15
Brpf1STRdStriatum dorsal region5.76
4.52
Brpf1STRvStriatum ventral region6.49
4.45
Brpf1THThalamus6.74
7.39
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00495619 21 456 476 LPALSHSEGEEDEDEEEDEGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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