AutismKB 2.0

Annotation Detail for USP7


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:USP7 ( HAUSP,TEF1 )
Gene Full Name: ubiquitin specific peptidase 7 (herpes virus-associated)
Band: 16p13.2
Quick LinksEntrez ID:7874; OMIM: 602519; Uniprot ID:UBP7_HUMAN; ENSEMBL ID: ENSG00000187555; HGNC ID: 12630
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst8 / 62319128
fetus57 / 564012101
neonate2 / 3109764
infant0 / 236200 
juvenile10 / 55556179
adult235 / 1939121121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor10 / 94178106
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor17 / 114246148
esophageal tumor2 / 17290115
gastrointestinal tumor15 / 119369125
germ cell tumor32 / 263845121
glioma11 / 106883102
head and neck tumor11 / 13630280
kidney tumor3 / 6895943
leukemia8 / 9584283
liver tumor15 / 96359155
lung tumor9 / 10312787
lymphoma8 / 71755111
non-neoplasia14 / 97250143
normal331 / 336030798
ovarian tumor7 / 7668291
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer18 / 102680175
retinoblastoma4 / 4635686
skin tumor9 / 12494972
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites7 / 40015174
bladder3 / 29757100
blood7 / 12347856
bone10 / 71655139
bone marrow3 / 4880161
brain52 / 110098947
cervix4 / 4817183
connective tissue5 / 14925533
ear2 / 16212123
embryonic tissue25 / 215722115
esophagus2 / 2020998
eye40 / 211054189
heart9 / 89626100
intestine31 / 234472132
kidney16 / 21177775
larynx5 / 24145207
liver19 / 20774391
lung47 / 336974139
lymph6 / 44270135
lymph node42 / 91610458
mammary gland28 / 153271182
mouth1 / 6705214
muscle9 / 10771583
nerve0 / 157680 
ovary7 / 10205168
pancreas20 / 21481293
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta20 / 28082571
prostate28 / 189345147
salivary gland3 / 20155148
skin23 / 210574109
spleen4 / 5395274
stomach11 / 96619113
testis78 / 330442236
thymus15 / 81131184
thyroid5 / 47473105
tonsil6 / 16999352
trachea2 / 5241338
umbilical cord1 / 1368073
uterus24 / 232878103
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201498_at
Cell line Expression level Expression bar
721_B_lymphoblasts189.2
Adipocyte13.5
AdrenalCortex16.8
Adrenalgland14.05
Amygdala112.6
Appendix11.85
AtrioventricularNode10.05
BDCA4+_DentriticCells188.95
Bonemarrow15.7
BronchialEpithelialCells28.85
CD105+_Endothelial352.85
CD14+_Monocytes278.35
CD19+_BCells(neg._sel.)279.7
CD33+_Myeloid303.35
CD34+213.95
CD4+_Tcells227.25
CD56+_NKCells247.85
CD71+_EarlyErythroid886.65
CD8+_Tcells224.45
CardiacMyocytes16.8
Caudatenucleus32.25
Cerebellum27.75
CerebellumPeduncles31.5
CiliaryGanglion9.9
CingulateCortex53.2
Colorectaladenocarcinoma42.35
DorsalRootGanglion9
FetalThyroid25.8
Fetalbrain153.1
Fetalliver38.9
Fetallung39.6
GlobusPallidus12
Heart11.7
Hypothalamus63.3
Kidney10.75
Leukemia_chronicMyelogenousK-56214.3
Leukemia_promyelocytic-HL-6051.3
Leukemialymphoblastic(MOLT-4)97.15
Liver17.3
Lung16.4
Lymphnode31.35
Lymphoma_burkitts(Daudi)52.25
Lymphoma_burkitts(Raji)77.7
MedullaOblongata34.7
OccipitalLobe36.55
OlfactoryBulb32.95
Ovary7.75
Pancreas10.45
PancreaticIslet27.9
ParietalLobe33.15
Pituitary33.3
Placenta46.2
Pons15.05
PrefrontalCortex194.25
Prostate104.45
Salivarygland12
SkeletalMuscle14.6
Skin11.4
SmoothMuscle15.65
Spinalcord32.25
SubthalamicNucleus22.4
SuperiorCervicalGanglion13.5
TemporalLobe22.55
Testis18.45
TestisGermCell24.65
TestisIntersitial8.65
TestisLeydigCell8.35
TestisSeminiferousTubule13.9
Thalamus32.15
Thymus100.1
Thyroid65.6
Tongue14.7
Tonsil23.2
Trachea10.9
TrigeminalGanglion11.95
Uterus95.55
UterusCorpus9.3
WholeBlood60.75
Wholebrain77.2
colon77.3
pineal_day213.54
pineal_night208.86
retina20.5
small_intestine74.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P245108
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.99 ± 0.66
Basal Forebrain5.5 ± 0.31
Basal Part of Pons5.29 ± 0.31
Cerebellar Cortex5.58 ± 0.32
Cerebellar Nuclei4.7 ± 0.47
Claustrum5.02 ± 0.57
Epithalamus5.15 ± 0.34
Frontal Lobe5.46 ± 0.45
Globus Pallidus4.52 ± 0.34
Hypothalamus5.2 ± 0.56
Insula5.57 ± 0.47
Limbic Lobe5.32 ± 0.56
Mesencephalon5.28 ± 0.57
Myelencephalon5.22 ± 0.58
Occipital Lobe4.79 ± 0.62
Parietal Lobe5.28 ± 0.46
Pontine Tegmentum5.17 ± 0.46
Striatum4.73 ± 0.58
Subthalamus5.24 ± 0.38
Temporal Lobe5.5 ± 0.42
Thalamus5.24 ± 0.47
White Matter4.45 ± 0.63
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Usp7CBCerebellum37.64
45.12
Usp7CTXCerebral cortex87.36
72.03
Usp7HIPHippocampal region42.85
74.51
Usp7HPFHippocampal formation53.81
68.39
Usp7HYHypothalamus33.05
25.33
Usp7LSXLateral septal complex30.19
22.2
Usp7MBMidbrain33.38
31.6
Usp7MYMedulla30.25
36.68
Usp7OLFOlfactory bulb69.01
63.44
Usp7PPons34.02
37.42
Usp7PALPallidum26.17
23.56
Usp7RHPRetrohippocampal region73.23
63.45
Usp7sAMYStriatum-like amygdalar nuclei43.15
31.19
Usp7STRStriatum38.7
29.32
Usp7STRdStriatum dorsal region37.7
29.22
Usp7STRvStriatum ventral region46.52
33.54
Usp7THThalamus40.31
37.5
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001413 21 488 508 CTKEEAIEHNYGGHDDDLSVR Peptide Atlas
UBP7_HUMAN_0 0 0 0 EVFGTFGIPFLLR PRIDE
UBP7_HUMAN_0 0 0 0 INDRFEFPEQLPLDEFLQK PRIDE
UBP7_HUMAN_394 14 394 407 FLTLPPVLHLQLMR PRIDE
UBP7_HUMAN_420 19 420 438 INDRFEFPEQLPLDEFLQK PRIDE
UBP7_HUMAN_679 12 679 690 FDKDHDVMLFLK PRIDE
UBP7_HUMAN_723 22 723 744 AGFIQDTSLILYEEVKPNLTER PRIDE
UBP7_HUMAN_829 12 829 840 LNTDPMLLQFFK PRIDE
UBP7_HUMAN_830 12 830 841 LNTDPMLLQFFK PRIDE
UBP7_HUMAN_997 13 997 1009 EVFGTFGIPFLLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved