AutismKB 2.0

Annotation Detail for CRELD1


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Basic Information Top
Gene Symbol:CRELD1 ( AVSD2,CIRRIN,DKFZp566D213 )
Gene Full Name: cysteine-rich with EGF-like domains 1
Band: 3p25.3
Quick LinksEntrez ID:78987; OMIM: 607170; Uniprot ID:CREL1_HUMAN; ENSEMBL ID: ENSG00000163703; HGNC ID: 14630
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus12 / 56401221
neonate2 / 3109764
infant0 / 236200 
juvenile2 / 5555635
adult115 / 193912159
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal147 / 336030743
ovarian tumor3 / 7668239
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood4 / 12347832
bone3 / 7165541
bone marrow0 / 488010 
brain34 / 110098930
cervix6 / 48171124
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus1 / 2020949
eye13 / 21105461
heart1 / 8962611
intestine6 / 23447225
kidney7 / 21177733
larynx1 / 2414541
liver3 / 20774314
lung20 / 33697459
lymph0 / 442700 
lymph node3 / 9161032
mammary gland7 / 15327145
mouth3 / 6705244
muscle0 / 1077150 
nerve0 / 157680 
ovary7 / 10205168
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta23 / 28082581
prostate12 / 18934563
salivary gland0 / 201550 
skin6 / 21057428
spleen4 / 5395274
stomach3 / 9661931
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203368_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.9
Adipocyte4.8
AdrenalCortex5.35
Adrenalgland4.3
Amygdala5.95
Appendix5.15
AtrioventricularNode3.9
BDCA4+_DentriticCells5.75
Bonemarrow5
BronchialEpithelialCells4.8
CD105+_Endothelial4.95
CD14+_Monocytes5.35
CD19+_BCells(neg._sel.)5.55
CD33+_Myeloid6.25
CD34+6.6
CD4+_Tcells11
CD56+_NKCells6.25
CD71+_EarlyErythroid4.85
CD8+_Tcells7.05
CardiacMyocytes7.2
Caudatenucleus9.05
Cerebellum6.85
CerebellumPeduncles6.75
CiliaryGanglion3.6
CingulateCortex6.85
Colorectaladenocarcinoma4.95
DorsalRootGanglion3.9
FetalThyroid10.45
Fetalbrain7.8
Fetalliver4.4
Fetallung4.4
GlobusPallidus3.8
Heart6.8
Hypothalamus9.5
Kidney4.05
Leukemia_chronicMyelogenousK-5626.25
Leukemia_promyelocytic-HL-604.4
Leukemialymphoblastic(MOLT-4)4.15
Liver6.75
Lung5.65
Lymphnode4.35
Lymphoma_burkitts(Daudi)6.5
Lymphoma_burkitts(Raji)7.45
MedullaOblongata5.9
OccipitalLobe7.2
OlfactoryBulb7.1
Ovary3.3
Pancreas4.1
PancreaticIslet5.7
ParietalLobe5.4
Pituitary6
Placenta5.55
Pons6.7
PrefrontalCortex6.95
Prostate20.5
Salivarygland3.9
SkeletalMuscle5.85
Skin3.95
SmoothMuscle5.7
Spinalcord5.6
SubthalamicNucleus4.7
SuperiorCervicalGanglion5.75
TemporalLobe4.8
Testis4.45
TestisGermCell4.6
TestisIntersitial4.35
TestisLeydigCell5.05
TestisSeminiferousTubule4.4
Thalamus6.5
Thymus3.95
Thyroid19.55
Tongue4.95
Tonsil4.8
Trachea4.2
TrigeminalGanglion5.15
Uterus4.85
UterusCorpus4.6
WholeBlood5.1
Wholebrain20.05
colon4.8
pineal_day26.4
pineal_night29.18
retina6.275
small_intestine4.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7186_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.4 ± 0.47
Basal Forebrain7.93 ± 0.49
Basal Part of Pons8 ± 0.36
Cerebellar Cortex7.68 ± 0.28
Cerebellar Nuclei7.75 ± 0.22
Claustrum8.28 ± 0.46
Epithalamus7.02 ± 0.36
Frontal Lobe7.87 ± 0.47
Globus Pallidus8.1 ± 0.28
Hypothalamus8.02 ± 0.35
Insula7.86 ± 0.46
Limbic Lobe8.27 ± 0.43
Mesencephalon7.96 ± 0.52
Myelencephalon8.01 ± 0.44
Occipital Lobe8.26 ± 0.43
Parietal Lobe8.11 ± 0.47
Pontine Tegmentum8.03 ± 0.35
Striatum8.15 ± 0.4
Subthalamus7.67 ± 0.35
Temporal Lobe8.02 ± 0.46
Thalamus7.96 ± 0.35
White Matter7.92 ± 0.73
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Creld1CBCerebellum43.63
76.59
Creld1CTXCerebral cortex100
100
Creld1HIPHippocampal region92.45
100
Creld1HPFHippocampal formation98.67
100
Creld1HYHypothalamus93.05
97.58
Creld1LSXLateral septal complex100
100
Creld1MBMidbrain100
100
Creld1MYMedulla91.16
100
Creld1OLFOlfactory bulb100
100
Creld1PPons83.03
100
Creld1PALPallidum100
100
Creld1RHPRetrohippocampal region100
100
Creld1sAMYStriatum-like amygdalar nuclei100
100
Creld1STRStriatum100
100
Creld1STRdStriatum dorsal region100
100
Creld1STRvStriatum ventral region100
100
Creld1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009672 13 221 233 CSGPEESNCLQCK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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