AutismKB 2.0

Annotation Detail for PRR14


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Basic Information Top
Gene Symbol:PRR14 ( DKFZp781A13198,MGC3121 )
Gene Full Name: proline rich 14
Band: 16p11.2
Quick LinksEntrez ID:78994; OMIM: NA; Uniprot ID:PRR14_HUMAN; ENSEMBL ID: ENSG00000156858; HGNC ID: 28458
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus12 / 56401221
neonate1 / 3109732
infant1 / 2362042
juvenile0 / 555560 
adult66 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor10 / 94178106
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor3 / 11424626
esophageal tumor2 / 17290115
gastrointestinal tumor5 / 11936941
germ cell tumor9 / 26384534
glioma9 / 10688384
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal80 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer2 / 10268019
retinoblastoma4 / 4635686
skin tumor31 / 124949248
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone4 / 7165555
bone marrow2 / 4880140
brain40 / 110098936
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus3 / 20209148
eye12 / 21105456
heart2 / 8962622
intestine8 / 23447234
kidney6 / 21177728
larynx0 / 241450 
liver1 / 2077434
lung16 / 33697447
lymph0 / 442700 
lymph node1 / 9161010
mammary gland10 / 15327165
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary7 / 10205168
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate5 / 18934526
salivary gland1 / 2015549
skin33 / 210574156
spleen1 / 5395218
stomach4 / 9661941
testis4 / 33044212
thymus3 / 8113136
thyroid0 / 474730 
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord0 / 136800 
uterus18 / 23287877
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218714_at
Cell line Expression level Expression bar
721_B_lymphoblasts176.75
Adipocyte57.65
AdrenalCortex89.85
Adrenalgland52.15
Amygdala61.95
Appendix43.45
AtrioventricularNode42
BDCA4+_DentriticCells182
Bonemarrow69.35
BronchialEpithelialCells71.1
CD105+_Endothelial279.7
CD14+_Monocytes206.15
CD19+_BCells(neg._sel.)184.7
CD33+_Myeloid235.7
CD34+247.4
CD4+_Tcells170.4
CD56+_NKCells334.1
CD71+_EarlyErythroid101.35
CD8+_Tcells238.3
CardiacMyocytes41.55
Caudatenucleus44.45
Cerebellum87.35
CerebellumPeduncles113.85
CiliaryGanglion26.4
CingulateCortex62.2
Colorectaladenocarcinoma71.35
DorsalRootGanglion40.75
FetalThyroid66.1
Fetalbrain115.65
Fetalliver34.4
Fetallung54
GlobusPallidus39.8
Heart166.5
Hypothalamus50.65
Kidney51.75
Leukemia_chronicMyelogenousK-56254.1
Leukemia_promyelocytic-HL-6080.2
Leukemialymphoblastic(MOLT-4)98.3
Liver77.95
Lung172.75
Lymphnode109.6
Lymphoma_burkitts(Daudi)94.55
Lymphoma_burkitts(Raji)115.3
MedullaOblongata44.75
OccipitalLobe23.9
OlfactoryBulb72.8
Ovary13.05
Pancreas30.5
PancreaticIslet44.3
ParietalLobe53.8
Pituitary56.25
Placenta47.5
Pons44.6
PrefrontalCortex72.3
Prostate90.75
Salivarygland43.75
SkeletalMuscle104.8
Skin43.25
SmoothMuscle35.2
Spinalcord58
SubthalamicNucleus53.3
SuperiorCervicalGanglion34.7
TemporalLobe45.7
Testis66.15
TestisGermCell48.6
TestisIntersitial48.35
TestisLeydigCell31.85
TestisSeminiferousTubule51.45
Thalamus43.55
Thymus117.95
Thyroid99.5
Tongue49.3
Tonsil72.75
Trachea43.85
TrigeminalGanglion52.95
Uterus131.25
UterusCorpus75.95
WholeBlood175.05
Wholebrain49.6
colon58.55
pineal_day119.8
pineal_night113.3
retina83.875
small_intestine40.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_47_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.16 ± 0.38
Basal Forebrain5.94 ± 0.25
Basal Part of Pons6.13 ± 0.29
Cerebellar Cortex6.43 ± 0.2
Cerebellar Nuclei5.81 ± 0.45
Claustrum6.66 ± 0.63
Epithalamus5.9 ± 0.34
Frontal Lobe5.81 ± 0.39
Globus Pallidus6.14 ± 0.45
Hypothalamus5.48 ± 0.36
Insula5.82 ± 0.46
Limbic Lobe6.17 ± 0.52
Mesencephalon6.01 ± 0.52
Myelencephalon6.07 ± 0.4
Occipital Lobe6.49 ± 0.57
Parietal Lobe6.07 ± 0.43
Pontine Tegmentum6.04 ± 0.52
Striatum5.96 ± 0.43
Subthalamus5.8 ± 0.24
Temporal Lobe6.02 ± 0.41
Thalamus6.09 ± 0.4
White Matter6.76 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prr14CBCerebellum16.22
30.35
Prr14CTXCerebral cortex76.86
66.64
Prr14HIPHippocampal region37.77
64.57
Prr14HPFHippocampal formation39.21
53.39
Prr14HYHypothalamus15.4
13.19
Prr14LSXLateral septal complex22.81
18.11
Prr14MBMidbrain9.78
11.04
Prr14MYMedulla7.07
9.37
Prr14OLFOlfactory bulb57.54
56.44
Prr14PPons9.23
11.83
Prr14PALPallidum20.34
19.32
Prr14RHPRetrohippocampal region42.68
39.11
Prr14sAMYStriatum-like amygdalar nuclei32.33
27.97
Prr14STRStriatum28.45
22.24
Prr14STRdStriatum dorsal region27
21.2
Prr14STRvStriatum ventral region34.76
24.81
Prr14THThalamus32.91
31.36
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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