AutismKB 2.0

Annotation Detail for METRN


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Basic Information Top
Gene Symbol:METRN ( C16orf23,MGC2601,c380A1.2 )
Gene Full Name: meteorin, glial cell differentiation regulator
Band: 16p13.3
Quick LinksEntrez ID:79006; OMIM: 610998; Uniprot ID:METRN_HUMAN; ENSEMBL ID: ENSG00000103260; HGNC ID: 14151
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult69 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor17 / 119369142
germ cell tumor6 / 26384522
glioma32 / 106883299
head and neck tumor3 / 13630222
kidney tumor4 / 6895958
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor12 / 103127116
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal84 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor11 / 12494988
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites6 / 40015149
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain79 / 110098971
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye14 / 21105466
heart0 / 896260 
intestine9 / 23447238
kidney6 / 21177728
larynx0 / 241450 
liver0 / 2077430 
lung18 / 33697453
lymph0 / 442700 
lymph node0 / 916100 
mammary gland7 / 15327145
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas13 / 21481260
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate17 / 18934589
salivary gland3 / 20155148
skin11 / 21057452
spleen0 / 539520 
stomach9 / 9661993
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219051_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts38.05
Adipocyte44.05
AdrenalCortex34.45
Adrenalgland46.6
Amygdala577.75
Appendix33.45
AtrioventricularNode28.15
BDCA4+_DentriticCells23.8
Bonemarrow32.4
BronchialEpithelialCells97.5
CD105+_Endothelial33.45
CD14+_Monocytes34.1
CD19+_BCells(neg._sel.)33.7
CD33+_Myeloid28.05
CD34+21.15
CD4+_Tcells34.55
CD56+_NKCells41.95
CD71+_EarlyErythroid33.6
CD8+_Tcells30.6
CardiacMyocytes49.3
Caudatenucleus436.8
Cerebellum130.5
CerebellumPeduncles133.95
CiliaryGanglion23.7
CingulateCortex119.65
Colorectaladenocarcinoma54.05
DorsalRootGanglion25.8
FetalThyroid33.8
Fetalbrain34.85
Fetalliver29
Fetallung27.65
GlobusPallidus55.35
Heart71.65
Hypothalamus300.25
Kidney35.15
Leukemia_chronicMyelogenousK-56230.1
Leukemia_promyelocytic-HL-6024.8
Leukemialymphoblastic(MOLT-4)19.15
Liver50.35
Lung40.75
Lymphnode26.45
Lymphoma_burkitts(Daudi)42.4
Lymphoma_burkitts(Raji)35.95
MedullaOblongata160.75
OccipitalLobe115.35
OlfactoryBulb55.25
Ovary22.45
Pancreas27.85
PancreaticIslet35.7
ParietalLobe85.55
Pituitary73.55
Placenta33.3
Pons112.35
PrefrontalCortex141.05
Prostate41
Salivarygland25.9
SkeletalMuscle38.1
Skin25.8
SmoothMuscle41.85
Spinalcord448.3
SubthalamicNucleus98.1
SuperiorCervicalGanglion37.15
TemporalLobe159.85
Testis28.3
TestisGermCell25.3
TestisIntersitial24
TestisLeydigCell31.9
TestisSeminiferousTubule28.05
Thalamus95.2
Thymus25.15
Thyroid505.05
Tongue33.35
Tonsil31.2
Trachea29.85
TrigeminalGanglion33
Uterus25.3
UterusCorpus17
WholeBlood17.9
Wholebrain424.05
colon25.55
pineal_day87.72
pineal_night74.12
retina206.525
small_intestine19.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_4907_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.47 ± 0.31
Basal Forebrain9.87 ± 0.23
Basal Part of Pons9 ± 0.35
Cerebellar Cortex9.16 ± 0.22
Cerebellar Nuclei9.03 ± 0.38
Claustrum8.77 ± 0.49
Epithalamus10.23 ± 0.78
Frontal Lobe9.46 ± 0.49
Globus Pallidus10.37 ± 0.4
Hypothalamus9.54 ± 0.37
Insula9.5 ± 0.38
Limbic Lobe9.34 ± 0.54
Mesencephalon9.67 ± 0.56
Myelencephalon9.67 ± 0.48
Occipital Lobe9.56 ± 0.42
Parietal Lobe9.46 ± 0.48
Pontine Tegmentum9.51 ± 0.45
Striatum10.57 ± 0.41
Subthalamus9.15 ± 0.8
Temporal Lobe9.47 ± 0.38
Thalamus9.8 ± 0.45
White Matter9.67 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MetrnCBCerebellum21.57
73.44
MetrnCTXCerebral cortex6.39
5.51
MetrnHIPHippocampal region2.82
3
MetrnHPFHippocampal formation2.78
2.67
MetrnHYHypothalamus2.52
1.85
MetrnLSXLateral septal complex2.84
2.45
MetrnMBMidbrain7.35
7.93
MetrnMYMedulla10.98
12.14
MetrnOLFOlfactory bulb12.74
9.45
MetrnPPons4.4
3.8
MetrnPALPallidum4.24
3.23
MetrnRHPRetrohippocampal region2.7
2.23
MetrnsAMYStriatum-like amygdalar nuclei2.1
1.44
MetrnSTRStriatum4.95
3.9
MetrnSTRdStriatum dorsal region5.52
4.69
MetrnSTRvStriatum ventral region5.33
3.18
MetrnTHThalamus11.04
9
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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