AutismKB 2.0

Annotation Detail for DBNDD1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DBNDD1 ( FLJ12582,MGC3101 )
Gene Full Name: dysbindin (dystrobrevin binding protein 1) domain containing 1
Band: 16q24.3
Quick LinksEntrez ID:79007; OMIM: NA; Uniprot ID:DBND1_HUMAN; ENSEMBL ID: ENSG00000003249; HGNC ID: 28455
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus21 / 56401237
neonate0 / 310970 
infant4 / 23620169
juvenile2 / 5555635
adult72 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor18 / 26384568
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal97 / 336030728
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS29 / 125680230
prostate cancer16 / 102680155
retinoblastoma4 / 4635686
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder2 / 2975767
blood3 / 12347824
bone1 / 7165513
bone marrow0 / 488010 
brain70 / 110098963
cervix3 / 4817162
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye12 / 21105456
heart1 / 8962611
intestine7 / 23447229
kidney3 / 21177714
larynx1 / 2414541
liver2 / 2077439
lung4 / 33697411
lymph0 / 442700 
lymph node2 / 9161021
mammary gland1 / 1532716
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary3 / 10205129
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate16 / 18934584
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach3 / 9661931
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222234_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.55
Adipocyte6.75
AdrenalCortex7.3
Adrenalgland5.75
Amygdala8.25
Appendix7.75
AtrioventricularNode6.75
BDCA4+_DentriticCells7.25
Bonemarrow6.7
BronchialEpithelialCells6.7
CD105+_Endothelial6.85
CD14+_Monocytes7.3
CD19+_BCells(neg._sel.)10.95
CD33+_Myeloid8.75
CD34+8.7
CD4+_Tcells7.5
CD56+_NKCells8.2
CD71+_EarlyErythroid6.4
CD8+_Tcells6.5
CardiacMyocytes11.65
Caudatenucleus6.2
Cerebellum5.85
CerebellumPeduncles7.8
CiliaryGanglion4.9
CingulateCortex7.35
Colorectaladenocarcinoma6.95
DorsalRootGanglion5.85
FetalThyroid6.75
Fetalbrain8.2
Fetalliver5.95
Fetallung5.7
GlobusPallidus5.05
Heart9.65
Hypothalamus13.4
Kidney5.55
Leukemia_chronicMyelogenousK-5626.2
Leukemia_promyelocytic-HL-606.1
Leukemialymphoblastic(MOLT-4)5.2
Liver18.25
Lung7.6
Lymphnode5.95
Lymphoma_burkitts(Daudi)8.75
Lymphoma_burkitts(Raji)9.65
MedullaOblongata6.35
OccipitalLobe6.2
OlfactoryBulb5.4
Ovary4.75
Pancreas5.5
PancreaticIslet7.35
ParietalLobe8
Pituitary8.05
Placenta6.9
Pons6.95
PrefrontalCortex19.75
Prostate7.85
Salivarygland6
SkeletalMuscle7.85
Skin6.25
SmoothMuscle7.8
Spinalcord7.35
SubthalamicNucleus6.35
SuperiorCervicalGanglion7.75
TemporalLobe8.85
Testis6
TestisGermCell5.85
TestisIntersitial5.7
TestisLeydigCell6.9
TestisSeminiferousTubule5.95
Thalamus9.7
Thymus5.1
Thyroid8.75
Tongue7.25
Tonsil6.8
Trachea5.65
TrigeminalGanglion15.15
Uterus5.6
UterusCorpus6.1
WholeBlood7.55
Wholebrain12.4
colon6.95
pineal_day8.58
pineal_night8.54
retina8.95
small_intestine6.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5190_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.84 ± 1.17
Basal Forebrain2.14 ± 0.16
Basal Part of Pons2.33 ± 1.02
Cerebellar Cortex3.05 ± 0.68
Cerebellar Nuclei2.51 ± 0.68
Claustrum2.99 ± 0.77
Epithalamus2.16 ± 0.84
Frontal Lobe2.3 ± 0.73
Globus Pallidus2.14 ± 0.45
Hypothalamus2.42 ± 0.7
Insula2.56 ± 0.63
Limbic Lobe2.44 ± 0.81
Mesencephalon2.69 ± 0.73
Myelencephalon2.64 ± 0.72
Occipital Lobe3.14 ± 0.86
Parietal Lobe2.73 ± 0.8
Pontine Tegmentum2.6 ± 0.7
Striatum2.17 ± 0.74
Subthalamus2.36 ± 0.72
Temporal Lobe2.64 ± 0.73
Thalamus2.95 ± 0.6
White Matter2.21 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dbndd1CBCerebellum14.64
19.93
Dbndd1CTXCerebral cortex2.79
1.92
Dbndd1HIPHippocampal region3.48
3.9
Dbndd1HPFHippocampal formation3.58
3.55
Dbndd1HYHypothalamus4.44
3.67
Dbndd1LSXLateral septal complex0.19
0.15
Dbndd1MBMidbrain5.8
5.53
Dbndd1MYMedulla8.68
10.06
Dbndd1OLFOlfactory bulb10.25
7.15
Dbndd1PPons7.98
9.61
Dbndd1PALPallidum2.01
1.89
Dbndd1RHPRetrohippocampal region4.05
3.3
Dbndd1sAMYStriatum-like amygdalar nuclei0.66
0.64
Dbndd1STRStriatum1.4
1.29
Dbndd1STRdStriatum dorsal region0.91
1.08
Dbndd1STRvStriatum ventral region4.15
2.76
Dbndd1THThalamus30.97
31.25
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved