AutismKB 2.0

Annotation Detail for TMUB2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TMUB2 ( MGC3123 )
Gene Full Name: transmembrane and ubiquitin-like domain containing 2
Band: 17q21
Quick LinksEntrez ID:79089; OMIM: NA; Uniprot ID:TMUB2_HUMAN; ENSEMBL ID: ENSG00000168591; HGNC ID: 28459
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst3 / 6231948
fetus32 / 56401256
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult111 / 193912157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor7 / 9417874
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor7 / 11936958
germ cell tumor5 / 26384518
glioma4 / 10688337
head and neck tumor1 / 1363027
kidney tumor4 / 6895958
leukemia5 / 9584252
liver tumor2 / 9635920
lung tumor7 / 10312767
lymphoma4 / 7175555
non-neoplasia2 / 9725020
normal161 / 336030747
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS18 / 125680143
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor3 / 12494924
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood12 / 12347897
bone5 / 7165569
bone marrow0 / 488010 
brain41 / 110098937
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus1 / 2020949
eye16 / 21105475
heart2 / 8962622
intestine11 / 23447246
kidney7 / 21177733
larynx0 / 241450 
liver2 / 2077439
lung23 / 33697468
lymph2 / 4427045
lymph node4 / 9161043
mammary gland12 / 15327178
mouth1 / 6705214
muscle4 / 10771537
nerve0 / 157680 
ovary4 / 10205139
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta21 / 28082574
prostate4 / 18934521
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach6 / 9661962
testis14 / 33044242
thymus1 / 8113112
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus15 / 23287864
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218419_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts16.95
Adipocyte13.15
AdrenalCortex16.35
Adrenalgland11.85
Amygdala15.4
Appendix13.6
AtrioventricularNode12.15
BDCA4+_DentriticCells15.05
Bonemarrow14.6
BronchialEpithelialCells11.05
CD105+_Endothelial12.9
CD14+_Monocytes14.75
CD19+_BCells(neg._sel.)14.75
CD33+_Myeloid17.5
CD34+23.75
CD4+_Tcells20.35
CD56+_NKCells28.4
CD71+_EarlyErythroid13.55
CD8+_Tcells19.7
CardiacMyocytes19
Caudatenucleus12.1
Cerebellum14.9
CerebellumPeduncles16.55
CiliaryGanglion10
CingulateCortex22.05
Colorectaladenocarcinoma14.55
DorsalRootGanglion12.05
FetalThyroid13.35
Fetalbrain12.7
Fetalliver11.95
Fetallung10.1
GlobusPallidus12.65
Heart24.45
Hypothalamus14.25
Kidney11.55
Leukemia_chronicMyelogenousK-56212.1
Leukemia_promyelocytic-HL-6011.85
Leukemialymphoblastic(MOLT-4)10.4
Liver17.55
Lung22.65
Lymphnode11.9
Lymphoma_burkitts(Daudi)17.2
Lymphoma_burkitts(Raji)19.95
MedullaOblongata10.95
OccipitalLobe12.1
OlfactoryBulb10.1
Ovary9.85
Pancreas10.35
PancreaticIslet14.65
ParietalLobe15.4
Pituitary14.7
Placenta14.1
Pons12.8
PrefrontalCortex21.25
Prostate25.4
Salivarygland11.1
SkeletalMuscle21.75
Skin12
SmoothMuscle13.7
Spinalcord15
SubthalamicNucleus12.65
SuperiorCervicalGanglion16.9
TemporalLobe12.15
Testis28.35
TestisGermCell16.7
TestisIntersitial14.2
TestisLeydigCell13.8
TestisSeminiferousTubule12.7
Thalamus14.15
Thymus17.65
Thyroid20.2
Tongue13.8
Tonsil12.6
Trachea11
TrigeminalGanglion15.85
Uterus10.5
UterusCorpus14.85
WholeBlood22.6
Wholebrain13.6
colon12.2
pineal_day20.56
pineal_night20.42
retina15.75
small_intestine11.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P36647
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.07 ± 0.2
Basal Forebrain7.06 ± 0.14
Basal Part of Pons7.23 ± 0.31
Cerebellar Cortex7.23 ± 0.31
Cerebellar Nuclei6.52 ± 0.74
Claustrum7.01 ± 0.3
Epithalamus6.91 ± 0.1
Frontal Lobe7.18 ± 0.31
Globus Pallidus6.55 ± 0.32
Hypothalamus6.94 ± 0.28
Insula7.12 ± 0.26
Limbic Lobe7.08 ± 0.3
Mesencephalon6.99 ± 0.24
Myelencephalon7.06 ± 0.32
Occipital Lobe6.83 ± 0.33
Parietal Lobe7.06 ± 0.32
Pontine Tegmentum6.96 ± 0.35
Striatum6.6 ± 0.29
Subthalamus6.98 ± 0.03
Temporal Lobe7.17 ± 0.28
Thalamus7.11 ± 0.29
White Matter6.82 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2010008E23RikCBCerebellum29.57
62.33
2010008E23RikCTXCerebral cortex99.17
96.48
2010008E23RikHIPHippocampal region87.82
100
2010008E23RikHPFHippocampal formation90.54
100
2010008E23RikHYHypothalamus55.15
51
2010008E23RikLSXLateral septal complex65.54
55.24
2010008E23RikMBMidbrain58.95
61.83
2010008E23RikMYMedulla52.17
67.09
2010008E23RikOLFOlfactory bulb98.74
100
2010008E23RikPPons48.14
59.43
2010008E23RikPALPallidum58.54
58.71
2010008E23RikRHPRetrohippocampal region92.12
97.78
2010008E23RiksAMYStriatum-like amygdalar nuclei72.17
63.26
2010008E23RikSTRStriatum60.35
50.76
2010008E23RikSTRdStriatum dorsal region58.71
49.05
2010008E23RikSTRvStriatum ventral region56.76
46.96
2010008E23RikTHThalamus82.05
82.26
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00096913 14 209 222 SLNITDNCVIHCHR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved