AutismKB 2.0

Annotation Detail for PPDPF


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Basic Information Top
Gene Symbol:PPDPF ( C20orf149,FLJ21046,MGC2479,dJ697K14.9 )
Gene Full Name: pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)
Band: 20q13.33
Quick LinksEntrez ID:79144; OMIM: NA; Uniprot ID:PPDPF_HUMAN; ENSEMBL ID: ENSG00000125534; HGNC ID: 16142
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst1 / 6231916
fetus34 / 56401260
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult273 / 1939121140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor32 / 94178339
cervical tumor6 / 34366174
chondrosarcoma11 / 82823132
colorectal tumor49 / 114246428
esophageal tumor0 / 172900 
gastrointestinal tumor24 / 119369201
germ cell tumor18 / 26384568
glioma20 / 106883187
head and neck tumor16 / 136302117
kidney tumor24 / 68959348
leukemia3 / 9584231
liver tumor13 / 96359134
lung tumor37 / 103127358
lymphoma2 / 7175527
non-neoplasia7 / 9725071
normal203 / 336030760
ovarian tumor22 / 76682286
pancreatic tumor52 / 104616497
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer39 / 102680379
retinoblastoma5 / 46356107
skin tumor25 / 124949200
soft tissue/muscle tissue tumor44 / 125191351
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites5 / 40015124
bladder0 / 297570 
blood3 / 12347824
bone15 / 71655209
bone marrow0 / 488010 
brain51 / 110098946
cervix9 / 48171186
connective tissue8 / 14925553
ear1 / 1621261
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye42 / 211054199
heart7 / 8962678
intestine56 / 234472238
kidney29 / 211777136
larynx2 / 2414582
liver17 / 20774381
lung54 / 336974160
lymph2 / 4427045
lymph node22 / 91610240
mammary gland51 / 153271332
mouth1 / 6705214
muscle26 / 107715241
nerve0 / 157680 
ovary30 / 102051293
pancreas56 / 214812260
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta10 / 28082535
prostate39 / 189345205
salivary gland14 / 20155694
skin31 / 210574147
spleen1 / 5395218
stomach7 / 9661972
testis17 / 33044251
thymus1 / 8113112
thyroid0 / 474730 
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord1 / 1368073
uterus27 / 232878115
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218010_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.2
Adipocyte9.15
AdrenalCortex3.25
Adrenalgland4.85
Amygdala14.65
Appendix5.8
AtrioventricularNode4.4
BDCA4+_DentriticCells8.35
Bonemarrow7.5
BronchialEpithelialCells15.6
CD105+_Endothelial8.45
CD14+_Monocytes7.65
CD19+_BCells(neg._sel.)18.15
CD33+_Myeloid7
CD34+10.3
CD4+_Tcells10.45
CD56+_NKCells9.6
CD71+_EarlyErythroid9.95
CD8+_Tcells8.6
CardiacMyocytes16.45
Caudatenucleus9.05
Cerebellum6.3
CerebellumPeduncles8.9
CiliaryGanglion4.15
CingulateCortex9.1
Colorectaladenocarcinoma39.4
DorsalRootGanglion6.25
FetalThyroid17.7
Fetalbrain12.35
Fetalliver4.5
Fetallung9.9
GlobusPallidus3.8
Heart15.75
Hypothalamus13
Kidney8.95
Leukemia_chronicMyelogenousK-5626.55
Leukemia_promyelocytic-HL-605.7
Leukemialymphoblastic(MOLT-4)13.1
Liver10.25
Lung33.35
Lymphnode7.55
Lymphoma_burkitts(Daudi)12.2
Lymphoma_burkitts(Raji)23.5
MedullaOblongata8.05
OccipitalLobe7.1
OlfactoryBulb11.65
Ovary8.1
Pancreas7
PancreaticIslet9.35
ParietalLobe8.3
Pituitary9.75
Placenta8.1
Pons6.95
PrefrontalCortex17.7
Prostate59.6
Salivarygland7.2
SkeletalMuscle6.6
Skin6.4
SmoothMuscle16
Spinalcord30.35
SubthalamicNucleus5.65
SuperiorCervicalGanglion6.55
TemporalLobe5.55
Testis16.05
TestisGermCell17.9
TestisIntersitial8.1
TestisLeydigCell9.15
TestisSeminiferousTubule9.7
Thalamus10.1
Thymus8.55
Thyroid64.1
Tongue25.35
Tonsil8.3
Trachea12.95
TrigeminalGanglion6.6
Uterus9.45
UterusCorpus5.25
WholeBlood13.45
Wholebrain6.9
colon10.1
pineal_day28.54
pineal_night24.44
retina17.825
small_intestine7.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_133_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.65 ± 0.27
Basal Forebrain6.93 ± 0.15
Basal Part of Pons6.93 ± 0.36
Cerebellar Cortex6.54 ± 0.24
Cerebellar Nuclei7.11 ± 0.3
Claustrum6.56 ± 0.32
Epithalamus6.61 ± 0.31
Frontal Lobe6.68 ± 0.34
Globus Pallidus7.53 ± 0.19
Hypothalamus6.91 ± 0.26
Insula6.59 ± 0.29
Limbic Lobe6.49 ± 0.33
Mesencephalon6.76 ± 0.39
Myelencephalon6.73 ± 0.3
Occipital Lobe6.43 ± 0.31
Parietal Lobe6.6 ± 0.3
Pontine Tegmentum6.63 ± 0.3
Striatum6.84 ± 0.2
Subthalamus6.78 ± 0.28
Temporal Lobe6.7 ± 0.29
Thalamus6.69 ± 0.29
White Matter7.9 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2700038C09RikCBCerebellum23.85
42.54
2700038C09RikCTXCerebral cortex31.25
23.08
2700038C09RikHIPHippocampal region29.03
35.49
2700038C09RikHPFHippocampal formation26.74
28.77
2700038C09RikHYHypothalamus6.32
4.73
2700038C09RikLSXLateral septal complex12.13
9
2700038C09RikMBMidbrain8.8
8.44
2700038C09RikMYMedulla12.69
15.15
2700038C09RikOLFOlfactory bulb38.68
31.76
2700038C09RikPPons6.92
8.34
2700038C09RikPALPallidum9.95
8.8
2700038C09RikRHPRetrohippocampal region24.36
21.56
2700038C09RiksAMYStriatum-like amygdalar nuclei19.43
13.83
2700038C09RikSTRStriatum13.41
9.9
2700038C09RikSTRdStriatum dorsal region13.39
10.15
2700038C09RikSTRvStriatum ventral region12.14
8.51
2700038C09RikTHThalamus15.06
12.97
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PPDPF_HUMAN_2 17 2 18 AAIPSSGSLVATHDYYR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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