AutismKB 2.0

Annotation Detail for DHRS11


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DHRS11 ( ARPG836,FLJ39232,MGC4172,SDR24C1 )
Gene Full Name: dehydrogenase/reductase (SDR family) member 11
Band: 17q12
Quick LinksEntrez ID:79154; OMIM: NA; Uniprot ID:DHR11_HUMAN; ENSEMBL ID: ENSG00000108272; HGNC ID: 28639
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult49 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor2 / 2638457
glioma5 / 10688346
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal77 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites6 / 40015149
bladder0 / 297570 
blood3 / 12347824
bone2 / 7165527
bone marrow0 / 488010 
brain22 / 110098919
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye12 / 21105456
heart6 / 8962666
intestine23 / 23447298
kidney4 / 21177718
larynx0 / 241450 
liver3 / 20774314
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland7 / 15327145
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate2 / 18934510
salivary gland0 / 201550 
skin6 / 21057428
spleen1 / 5395218
stomach5 / 9661951
testis8 / 33044224
thymus0 / 811310 
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218756_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.8
Adipocyte6.9
AdrenalCortex7.45
Adrenalgland5.8
Amygdala7.25
Appendix10.15
AtrioventricularNode5.9
BDCA4+_DentriticCells6.35
Bonemarrow6.75
BronchialEpithelialCells6.2
CD105+_Endothelial17
CD14+_Monocytes6.85
CD19+_BCells(neg._sel.)6.6
CD33+_Myeloid8
CD34+21.55
CD4+_Tcells6.7
CD56+_NKCells7.25
CD71+_EarlyErythroid7.15
CD8+_Tcells5.95
CardiacMyocytes8.5
Caudatenucleus5.95
Cerebellum5.35
CerebellumPeduncles7.8
CiliaryGanglion5.35
CingulateCortex7.2
Colorectaladenocarcinoma12.65
DorsalRootGanglion5.5
FetalThyroid7.3
Fetalbrain6.3
Fetalliver5.75
Fetallung5.3
GlobusPallidus5.3
Heart16.95
Hypothalamus7.3
Kidney8.2
Leukemia_chronicMyelogenousK-56233.1
Leukemia_promyelocytic-HL-605.95
Leukemialymphoblastic(MOLT-4)5.5
Liver8.95
Lung7.05
Lymphnode5.45
Lymphoma_burkitts(Daudi)8.6
Lymphoma_burkitts(Raji)9.3
MedullaOblongata6.75
OccipitalLobe5.9
OlfactoryBulb5.1
Ovary4.6
Pancreas6.1
PancreaticIslet7.2
ParietalLobe7.15
Pituitary7.65
Placenta6.45
Pons6.5
PrefrontalCortex12.1
Prostate7.35
Salivarygland5.35
SkeletalMuscle8.35
Skin5.75
SmoothMuscle7.25
Spinalcord6.95
SubthalamicNucleus6.15
SuperiorCervicalGanglion7.9
TemporalLobe6.15
Testis15.4
TestisGermCell6.65
TestisIntersitial5.65
TestisLeydigCell6.9
TestisSeminiferousTubule7.35
Thalamus6.85
Thymus4.9
Thyroid8.45
Tongue6.75
Tonsil6.45
Trachea5.5
TrigeminalGanglion9.65
Uterus5.1
UterusCorpus6.3
WholeBlood7
Wholebrain15
colon378.9
pineal_day310.96
pineal_night306.4
retina41.5
small_intestine754.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8682_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.99 ± 0.79
Basal Forebrain3.01 ± 0.86
Basal Part of Pons2.84 ± 0.73
Cerebellar Cortex2.71 ± 0.72
Cerebellar Nuclei3.04 ± 0.67
Claustrum3.02 ± 0.66
Epithalamus2.35 ± 0.75
Frontal Lobe2.98 ± 0.63
Globus Pallidus2.68 ± 0.84
Hypothalamus2.85 ± 0.5
Insula2.52 ± 0.87
Limbic Lobe2.77 ± 0.63
Mesencephalon2.94 ± 0.65
Myelencephalon2.82 ± 0.72
Occipital Lobe2.61 ± 0.62
Parietal Lobe2.96 ± 0.72
Pontine Tegmentum2.96 ± 0.76
Striatum2.94 ± 0.75
Subthalamus2.94 ± 0.56
Temporal Lobe2.91 ± 0.67
Thalamus2.84 ± 0.65
White Matter1.72 ± 1.04
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
BC022224CBCerebellum17.37
19.04
BC022224CTXCerebral cortex32.18
23.77
BC022224HIPHippocampal region35.5
39.69
BC022224HPFHippocampal formation35.59
34.84
BC022224HYHypothalamus14.15
10.28
BC022224LSXLateral septal complex3
2.27
BC022224MBMidbrain9.5
9.39
BC022224MYMedulla20.99
24.39
BC022224OLFOlfactory bulb42.28
36.46
BC022224PPons18.63
20.88
BC022224PALPallidum21.05
17.88
BC022224RHPRetrohippocampal region35.1
27.73
BC022224sAMYStriatum-like amygdalar nuclei53.41
39.7
BC022224STRStriatum20.56
15.12
BC022224STRdStriatum dorsal region15.85
11.45
BC022224STRvStriatum ventral region36
25.84
BC022224THThalamus15.45
11.8
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000722 16 193 208 ATCISPGVVETQFAFK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved