AutismKB 2.0

Annotation Detail for CRELD2


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Basic Information Top
Gene Symbol:CRELD2 ( DKFZp667O055,MGC11256 )
Gene Full Name: cysteine-rich with EGF-like domains 2
Band: 22q13.33
Quick LinksEntrez ID:79174; OMIM: 607171; Uniprot ID:CREL2_HUMAN; ENSEMBL ID: ENSG00000184164; HGNC ID: 28150
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst0 / 623190 
fetus26 / 56401246
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor13 / 94178138
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor11 / 26384541
glioma3 / 10688328
head and neck tumor3 / 13630222
kidney tumor5 / 6895972
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal96 / 336030728
ovarian tumor5 / 7668265
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer11 / 102680107
retinoblastoma1 / 4635621
skin tumor8 / 12494964
soft tissue/muscle tissue tumor15 / 125191119
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood7 / 12347856
bone8 / 71655111
bone marrow1 / 4880120
brain26 / 110098923
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye2 / 2110549
heart4 / 8962644
intestine3 / 23447212
kidney6 / 21177728
larynx0 / 241450 
liver3 / 20774314
lung10 / 33697429
lymph0 / 442700 
lymph node4 / 9161043
mammary gland13 / 15327184
mouth1 / 6705214
muscle12 / 107715111
nerve1 / 1576863
ovary11 / 102051107
pancreas19 / 21481288
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta8 / 28082528
prostate14 / 18934573
salivary gland0 / 201550 
skin12 / 21057456
spleen2 / 5395237
stomach2 / 9661920
testis14 / 33044242
thymus4 / 8113149
thyroid2 / 4747342
tonsil4 / 16999235
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218358_at
Cell line Expression level Expression bar
721_B_lymphoblasts172.9
Adipocyte83.85
AdrenalCortex31.1
Adrenalgland54.4
Amygdala77.4
Appendix29.75
AtrioventricularNode56.3
BDCA4+_DentriticCells327.95
Bonemarrow98.6
BronchialEpithelialCells136.4
CD105+_Endothelial75.9
CD14+_Monocytes113
CD19+_BCells(neg._sel.)138.7
CD33+_Myeloid173.15
CD34+146.1
CD4+_Tcells120.8
CD56+_NKCells230.1
CD71+_EarlyErythroid30.6
CD8+_Tcells117.95
CardiacMyocytes105.5
Caudatenucleus54.2
Cerebellum43.5
CerebellumPeduncles59.5
CiliaryGanglion14.3
CingulateCortex51.65
Colorectaladenocarcinoma74.6
DorsalRootGanglion30.05
FetalThyroid186.6
Fetalbrain68.1
Fetalliver66.65
Fetallung128.85
GlobusPallidus27.7
Heart85.55
Hypothalamus144.8
Kidney56.1
Leukemia_chronicMyelogenousK-56240.5
Leukemia_promyelocytic-HL-6044.65
Leukemialymphoblastic(MOLT-4)42.65
Liver216
Lung251.7
Lymphnode110.5
Lymphoma_burkitts(Daudi)77.05
Lymphoma_burkitts(Raji)82.2
MedullaOblongata36.95
OccipitalLobe36.65
OlfactoryBulb113.05
Ovary59.6
Pancreas250
PancreaticIslet408.5
ParietalLobe36.05
Pituitary194.1
Placenta72.95
Pons29.4
PrefrontalCortex93.95
Prostate242
Salivarygland71.15
SkeletalMuscle30.85
Skin22.5
SmoothMuscle186.9
Spinalcord80
SubthalamicNucleus29
SuperiorCervicalGanglion37.6
TemporalLobe43
Testis211.95
TestisGermCell110.4
TestisIntersitial115.35
TestisLeydigCell98.45
TestisSeminiferousTubule95.2
Thalamus55.5
Thymus78.55
Thyroid545.95
Tongue14.25
Tonsil72.8
Trachea236.4
TrigeminalGanglion29.3
Uterus101.35
UterusCorpus31.7
WholeBlood60.85
Wholebrain85.35
colon111.05
pineal_day212.76
pineal_night212.4
retina94.95
small_intestine163.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6904_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.51 ± 0.58
Basal Forebrain6.94 ± 0.23
Basal Part of Pons7.13 ± 0.35
Cerebellar Cortex7.04 ± 0.36
Cerebellar Nuclei6.73 ± 0.31
Claustrum6.4 ± 0.52
Epithalamus7.5 ± 0.55
Frontal Lobe7.08 ± 0.36
Globus Pallidus7.23 ± 0.12
Hypothalamus7.31 ± 0.33
Insula7.2 ± 0.3
Limbic Lobe6.93 ± 0.39
Mesencephalon6.86 ± 0.43
Myelencephalon7.01 ± 0.38
Occipital Lobe6.72 ± 0.32
Parietal Lobe6.86 ± 0.35
Pontine Tegmentum6.97 ± 0.37
Striatum7.26 ± 0.37
Subthalamus7 ± 0.47
Temporal Lobe7.08 ± 0.35
Thalamus7.03 ± 0.32
White Matter7.73 ± 0.15
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Creld2CBCerebellum22.9
27.28
Creld2CTXCerebral cortex36.62
25.7
Creld2HIPHippocampal region27.04
33.75
Creld2HPFHippocampal formation27.49
28.01
Creld2HYHypothalamus27.88
21.22
Creld2LSXLateral septal complex19.82
13.43
Creld2MBMidbrain23.25
20.22
Creld2MYMedulla21.72
21.19
Creld2OLFOlfactory bulb38.98
28.56
Creld2PPons20.23
19.37
Creld2PALPallidum19.59
15.88
Creld2RHPRetrohippocampal region28.55
20.62
Creld2sAMYStriatum-like amygdalar nuclei28.95
24.07
Creld2STRStriatum27.15
19.72
Creld2STRdStriatum dorsal region25.65
18.88
Creld2STRvStriatum ventral region36.03
23.57
Creld2THThalamus17.41
15.78
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00007076 13 110 122 SEYPDLFEWFCVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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