AutismKB 2.0

Annotation Detail for FSD1


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Basic Information Top
Gene Symbol:FSD1 ( GLFND,MGC3213,MIR1 )
Gene Full Name: fibronectin type III and SPRY domain containing 1
Band: 19p13.3
Quick LinksEntrez ID:79187; OMIM: 609828; Uniprot ID:FSD1_HUMAN; ENSEMBL ID: ENSG00000105255; HGNC ID: 13745
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus33 / 56401258
neonate0 / 310970 
infant8 / 23620338
juvenile1 / 5555617
adult38 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor16 / 26384560
glioma10 / 10688393
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal110 / 336030732
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS41 / 125680326
prostate cancer0 / 1026800 
retinoblastoma14 / 46356302
skin tumor9 / 12494972
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain120 / 1100989108
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye16 / 21105475
heart0 / 896260 
intestine2 / 2344728
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth2 / 6705229
muscle2 / 10771518
nerve1 / 1576863
ovary3 / 10205129
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach0 / 966190 
testis15 / 33044245
thymus1 / 8113112
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219170_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.15
Adipocyte5.2
AdrenalCortex4.65
Adrenalgland4.2
Amygdala57.7
Appendix4.5
AtrioventricularNode3.25
BDCA4+_DentriticCells5.25
Bonemarrow4.5
BronchialEpithelialCells5.75
CD105+_Endothelial4.7
CD14+_Monocytes4.95
CD19+_BCells(neg._sel.)5.25
CD33+_Myeloid6.25
CD34+6.15
CD4+_Tcells5.45
CD56+_NKCells13.95
CD71+_EarlyErythroid4.45
CD8+_Tcells6
CardiacMyocytes10.45
Caudatenucleus7.5
Cerebellum15.4
CerebellumPeduncles14.95
CiliaryGanglion3.6
CingulateCortex51
Colorectaladenocarcinoma16.2
DorsalRootGanglion4
FetalThyroid4.6
Fetalbrain66.55
Fetalliver4.6
Fetallung4
GlobusPallidus7.55
Heart19.3
Hypothalamus36.1
Kidney3.8
Leukemia_chronicMyelogenousK-5624.7
Leukemia_promyelocytic-HL-604.35
Leukemialymphoblastic(MOLT-4)8.25
Liver19.25
Lung7.55
Lymphnode3.9
Lymphoma_burkitts(Daudi)7
Lymphoma_burkitts(Raji)52.5
MedullaOblongata11
OccipitalLobe21.45
OlfactoryBulb4.05
Ovary3.05
Pancreas3.9
PancreaticIslet4.8
ParietalLobe20.55
Pituitary6.35
Placenta5.05
Pons7.55
PrefrontalCortex79.1
Prostate12.15
Salivarygland3.8
SkeletalMuscle5.85
Skin3.65
SmoothMuscle6
Spinalcord6.3
SubthalamicNucleus17.45
SuperiorCervicalGanglion5.3
TemporalLobe13.45
Testis9.9
TestisGermCell4.35
TestisIntersitial5.75
TestisLeydigCell7.05
TestisSeminiferousTubule6.4
Thalamus50.15
Thymus5.9
Thyroid7.55
Tongue4.75
Tonsil4.75
Trachea4.4
TrigeminalGanglion4.7
Uterus7.2
UterusCorpus5.5
WholeBlood5.55
Wholebrain114.1
colon5.25
pineal_day5.82
pineal_night5.64
retina6.95
small_intestine5.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14922_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.68 ± 0.68
Basal Forebrain4.28 ± 0.47
Basal Part of Pons5.42 ± 0.64
Cerebellar Cortex5.06 ± 0.62
Cerebellar Nuclei4.1 ± 0.49
Claustrum4.13 ± 0.91
Epithalamus4.14 ± 1.11
Frontal Lobe4.98 ± 0.71
Globus Pallidus2.89 ± 0.83
Hypothalamus4.56 ± 0.79
Insula4.97 ± 0.48
Limbic Lobe4.68 ± 0.73
Mesencephalon4.47 ± 0.73
Myelencephalon4.57 ± 0.86
Occipital Lobe4.2 ± 0.76
Parietal Lobe4.69 ± 0.71
Pontine Tegmentum4.48 ± 0.71
Striatum3.53 ± 0.84
Subthalamus4.66 ± 0.43
Temporal Lobe4.99 ± 0.57
Thalamus4.6 ± 0.66
White Matter2.86 ± 0.73
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fsd1CBCerebellum22.88
25.19
Fsd1CTXCerebral cortex71.98
53.11
Fsd1HIPHippocampal region28.12
29.08
Fsd1HPFHippocampal formation37.31
33.53
Fsd1HYHypothalamus56.72
44.74
Fsd1LSXLateral septal complex51.83
37.3
Fsd1MBMidbrain56.82
51.41
Fsd1MYMedulla57.53
67.67
Fsd1OLFOlfactory bulb46.08
35.37
Fsd1PPons54.08
59.41
Fsd1PALPallidum58.49
53.29
Fsd1RHPRetrohippocampal region57.75
43.39
Fsd1sAMYStriatum-like amygdalar nuclei34.12
23.81
Fsd1STRStriatum39.64
27.58
Fsd1STRdStriatum dorsal region35.82
24.95
Fsd1STRvStriatum ventral region50.8
33.94
Fsd1THThalamus71.93
59.39
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00496436 20 252 271 AVAGEFSEPVTLETPAFMFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018