AutismKB 2.0

Annotation Detail for ZNF557


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Basic Information Top
Gene Symbol:ZNF557 ( FLJ96454,MGC4054 )
Gene Full Name: zinc finger protein 557
Band: 19p13.2
Quick LinksEntrez ID:79230; OMIM: NA; Uniprot ID:ZN557_HUMAN; ENSEMBL ID: ENSG00000130544; HGNC ID: 28632
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal32 / 33603079
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow1 / 4880120
brain14 / 110098912
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart1 / 8962611
intestine4 / 23447217
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate4 / 18934521
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach1 / 9661910
testis2 / 3304426
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220444_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.35
Adipocyte4.05
AdrenalCortex4.6
Adrenalgland3.5
Amygdala4.25
Appendix4.5
AtrioventricularNode3.25
BDCA4+_DentriticCells4.5
Bonemarrow4.1
BronchialEpithelialCells4.05
CD105+_Endothelial4.15
CD14+_Monocytes4.35
CD19+_BCells(neg._sel.)4.3
CD33+_Myeloid5.2
CD34+5.25
CD4+_Tcells4.45
CD56+_NKCells4.9
CD71+_EarlyErythroid3.85
CD8+_Tcells4.05
CardiacMyocytes5.3
Caudatenucleus3.7
Cerebellum3.35
CerebellumPeduncles4.7
CiliaryGanglion5
CingulateCortex4.25
Colorectaladenocarcinoma4.1
DorsalRootGanglion3.25
FetalThyroid4
Fetalbrain4.1
Fetalliver3.6
Fetallung3.4
GlobusPallidus3.1
Heart5.5
Hypothalamus4.45
Kidney3.4
Leukemia_chronicMyelogenousK-5623.7
Leukemia_promyelocytic-HL-603.65
Leukemialymphoblastic(MOLT-4)3.25
Liver5.5
Lung4.55
Lymphnode3.5
Lymphoma_burkitts(Daudi)5.25
Lymphoma_burkitts(Raji)5.8
MedullaOblongata3.75
OccipitalLobe3.7
OlfactoryBulb3.25
Ovary2.8
Pancreas3.35
PancreaticIslet4.4
ParietalLobe4.4
Pituitary4.8
Placenta4.25
Pons3.9
PrefrontalCortex5.05
Prostate4.8
Salivarygland3.35
SkeletalMuscle4.95
Skin3.55
SmoothMuscle4.65
Spinalcord4.4
SubthalamicNucleus3.85
SuperiorCervicalGanglion4.8
TemporalLobe3.75
Testis3.5
TestisGermCell3.4
TestisIntersitial3.45
TestisLeydigCell4.1
TestisSeminiferousTubule3.55
Thalamus4.2
Thymus3.25
Thyroid5.1
Tongue4.1
Tonsil4
Trachea3.4
TrigeminalGanglion4.5
Uterus3.35
UterusCorpus3.8
WholeBlood4.55
Wholebrain3.45
colon4.15
pineal_day5.08
pineal_night5
retina4.95
small_intestine3.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P90021
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.95 ± 0.47
Basal Forebrain4.63 ± 0.23
Basal Part of Pons4.73 ± 0.69
Cerebellar Cortex5.12 ± 0.25
Cerebellar Nuclei4.38 ± 0.56
Claustrum4.64 ± 0.91
Epithalamus4.64 ± 0.36
Frontal Lobe4.79 ± 0.46
Globus Pallidus4.53 ± 0.54
Hypothalamus4.82 ± 0.47
Insula4.76 ± 0.29
Limbic Lobe4.85 ± 0.44
Mesencephalon4.83 ± 0.53
Myelencephalon4.74 ± 0.55
Occipital Lobe5.04 ± 0.39
Parietal Lobe4.85 ± 0.51
Pontine Tegmentum4.87 ± 0.5
Striatum4.56 ± 0.63
Subthalamus5.04 ± 0.48
Temporal Lobe4.83 ± 0.45
Thalamus4.69 ± 0.55
White Matter5.08 ± 0.31
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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