AutismKB 2.0

Annotation Detail for BCL2L14


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Basic Information Top
Gene Symbol:BCL2L14 ( BCLG )
Gene Full Name: BCL2-like 14 (apoptosis facilitator)
Band: 12p13.2
Quick LinksEntrez ID:79370; OMIM: 606126; Uniprot ID:B2L14_HUMAN; ENSEMBL ID: ENSG00000121380; HGNC ID: 16657
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult10 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal45 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine6 / 23447225
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis30 / 33044290
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221241_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.6
Adipocyte3.65
AdrenalCortex3.85
Adrenalgland3.1
Amygdala3.95
Appendix3.75
AtrioventricularNode2.8
BDCA4+_DentriticCells4
Bonemarrow3.65
BronchialEpithelialCells3.6
CD105+_Endothelial3.75
CD14+_Monocytes3.95
CD19+_BCells(neg._sel.)3.9
CD33+_Myeloid4.65
CD34+4.6
CD4+_Tcells3.95
CD56+_NKCells4.5
CD71+_EarlyErythroid3.45
CD8+_Tcells3.5
CardiacMyocytes4.9
Caudatenucleus3.3
Cerebellum3
CerebellumPeduncles4.15
CiliaryGanglion2.6
CingulateCortex3.8
Colorectaladenocarcinoma3.65
DorsalRootGanglion3.15
FetalThyroid3.55
Fetalbrain3.7
Fetalliver3.15
Fetallung3.15
GlobusPallidus2.65
Heart4.65
Hypothalamus4.05
Kidney2.95
Leukemia_chronicMyelogenousK-5623.35
Leukemia_promyelocytic-HL-603.25
Leukemialymphoblastic(MOLT-4)2.95
Liver5
Lung4.05
Lymphnode3.2
Lymphoma_burkitts(Daudi)4.65
Lymphoma_burkitts(Raji)5.05
MedullaOblongata3.35
OccipitalLobe3.3
OlfactoryBulb2.85
Ovary2.4
Pancreas2.95
PancreaticIslet3.95
ParietalLobe3.85
Pituitary4.35
Placenta3.8
Pons3.5
PrefrontalCortex4.55
Prostate4.65
Salivarygland2.9
SkeletalMuscle4.15
Skin2.75
SmoothMuscle4.15
Spinalcord3.95
SubthalamicNucleus3.35
SuperiorCervicalGanglion4.2
TemporalLobe3.3
Testis11.55
TestisGermCell4.95
TestisIntersitial5.4
TestisLeydigCell5.5
TestisSeminiferousTubule3.35
Thalamus3.7
Thymus2.95
Thyroid4.65
Tongue3.55
Tonsil3.6
Trachea3.1
TrigeminalGanglion4.05
Uterus3.05
UterusCorpus3.25
WholeBlood4
Wholebrain3.2
colon3.7
pineal_day4.58
pineal_night4.48
retina4.4
small_intestine3.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5827_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.18 ± 1.08
Basal Forebrain1.72 ± 0.23
Basal Part of Pons1.44 ± 0.44
Cerebellar Cortex1.5 ± 0.56
Cerebellar Nuclei1.98 ± 0.68
Claustrum2.52 ± 0.79
Epithalamus1.38 ± 0.74
Frontal Lobe1.59 ± 0.64
Globus Pallidus2.24 ± 0.31
Hypothalamus1.78 ± 0.68
Insula1.6 ± 0.58
Limbic Lobe1.79 ± 0.75
Mesencephalon1.91 ± 0.7
Myelencephalon1.79 ± 0.69
Occipital Lobe1.85 ± 0.71
Parietal Lobe1.76 ± 0.89
Pontine Tegmentum1.77 ± 0.68
Striatum1.98 ± 0.8
Subthalamus1.87 ± 0.66
Temporal Lobe1.6 ± 0.62
Thalamus1.72 ± 0.63
White Matter2.19 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Bcl2l14CBCerebellum0.64
1.75
Bcl2l14CTXCerebral cortex2.02
1.6
Bcl2l14HIPHippocampal region0.44
0.37
Bcl2l14HPFHippocampal formation0.3
0.26
Bcl2l14HYHypothalamus0.04
0.02
Bcl2l14LSXLateral septal complex0.02
0
Bcl2l14MBMidbrain0.17
0.77
Bcl2l14MYMedulla0.11
0.48
Bcl2l14OLFOlfactory bulb0.16
0.24
Bcl2l14PPons0.1
0.13
Bcl2l14PALPallidum0.05
0.11
Bcl2l14RHPRetrohippocampal region0.06
0.1
Bcl2l14sAMYStriatum-like amygdalar nuclei0.05
0.03
Bcl2l14STRStriatum0.13
0.15
Bcl2l14STRdStriatum dorsal region0.15
0.17
Bcl2l14STRvStriatum ventral region0.2
0.24
Bcl2l14THThalamus0.51
0.94
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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