AutismKB 2.0

Annotation Detail for CALB2


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Basic Information Top
Gene Symbol:CALB2 ( CAB29,CAL2,CR )
Gene Full Name: calbindin 2
Band: 16q22.2
Quick LinksEntrez ID:794; OMIM: 114051; Uniprot ID:CALB2_HUMAN; ENSEMBL ID: ENSG00000172137; HGNC ID: 1435
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal80 / 336030723
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain66 / 110098959
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye10 / 21105447
heart2 / 8962622
intestine6 / 23447225
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node3 / 9161032
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve2 / 15768126
ovary4 / 10205139
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach7 / 9661972
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205428_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.9
Adipocyte28.25
AdrenalCortex12.2
Adrenalgland14.5
Amygdala61.85
Appendix11.65
AtrioventricularNode8.7
BDCA4+_DentriticCells9.45
Bonemarrow14.2
BronchialEpithelialCells11.6
CD105+_Endothelial10.9
CD14+_Monocytes9.2
CD19+_BCells(neg._sel.)10.15
CD33+_Myeloid12.9
CD34+13.2
CD4+_Tcells11.6
CD56+_NKCells9.9
CD71+_EarlyErythroid10.95
CD8+_Tcells8.85
CardiacMyocytes15.7
Caudatenucleus11.35
Cerebellum85.35
CerebellumPeduncles164.6
CiliaryGanglion8.1
CingulateCortex25.2
Colorectaladenocarcinoma11.75
DorsalRootGanglion8.8
FetalThyroid11.55
Fetalbrain31.85
Fetalliver10.15
Fetallung9.75
GlobusPallidus8.55
Heart14.8
Hypothalamus301
Kidney10.15
Leukemia_chronicMyelogenousK-56210.4
Leukemia_promyelocytic-HL-609.6
Leukemialymphoblastic(MOLT-4)8.35
Liver15
Lung13.05
Lymphnode10.35
Lymphoma_burkitts(Daudi)16.45
Lymphoma_burkitts(Raji)16.35
MedullaOblongata13.65
OccipitalLobe12.85
OlfactoryBulb9.25
Ovary8.7
Pancreas9.35
PancreaticIslet12.65
ParietalLobe13.7
Pituitary30.5
Placenta11.15
Pons11.1
PrefrontalCortex15.25
Prostate12.55
Salivarygland9
SkeletalMuscle13.05
Skin8.85
SmoothMuscle13.55
Spinalcord19.2
SubthalamicNucleus14.3
SuperiorCervicalGanglion12.8
TemporalLobe13.6
Testis35.3
TestisGermCell10.1
TestisIntersitial12.3
TestisLeydigCell16.5
TestisSeminiferousTubule11.4
Thalamus157.65
Thymus10.65
Thyroid14.7
Tongue11.4
Tonsil11.45
Trachea10
TrigeminalGanglion11.45
Uterus9.2
UterusCorpus14
WholeBlood11.6
Wholebrain32.25
colon13.45
pineal_day12.02
pineal_night12.66
retina32.325
small_intestine12.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14719_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.93 ± 0.73
Basal Forebrain10.93 ± 0.46
Basal Part of Pons11.3 ± 0.22
Cerebellar Cortex11.02 ± 0.76
Cerebellar Nuclei10.79 ± 0.71
Claustrum8.94 ± 1.13
Epithalamus10.58 ± 0.99
Frontal Lobe9.62 ± 1.05
Globus Pallidus9.71 ± 0.81
Hypothalamus11.75 ± 0.84
Insula10.73 ± 0.71
Limbic Lobe9.52 ± 1.25
Mesencephalon10.05 ± 1.3
Myelencephalon10.16 ± 1.13
Occipital Lobe9.27 ± 1.11
Parietal Lobe9.95 ± 0.81
Pontine Tegmentum9.97 ± 1.06
Striatum9.22 ± 0.76
Subthalamus11.76 ± 1.02
Temporal Lobe10.43 ± 0.95
Thalamus10.8 ± 1
White Matter5.82 ± 1.51
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Calb2CBCerebellum100
100
Calb2CTXCerebral cortex28.54
21.79
Calb2HIPHippocampal region24.25
38.52
Calb2HPFHippocampal formation28.38
34.37
Calb2HYHypothalamus99.09
99.46
Calb2LSXLateral septal complex38.49
45.68
Calb2MBMidbrain85.01
98.34
Calb2MYMedulla59.66
89.49
Calb2OLFOlfactory bulb96.99
100
Calb2PPons74.29
99.88
Calb2PALPallidum59.04
68.17
Calb2RHPRetrohippocampal region34.75
27.74
Calb2sAMYStriatum-like amygdalar nuclei83.75
86.46
Calb2STRStriatum22.73
19.15
Calb2STRdStriatum dorsal region11.11
6.74
Calb2STRvStriatum ventral region24.15
16.72
Calb2THThalamus63.98
95.39
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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