AutismKB 2.0

Annotation Detail for PLA2G7


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Basic Information Top
Gene Symbol:PLA2G7 ( LDL-PLA2,LP-PLA2,PAFAH )
Gene Full Name: phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
Band: 6p12.3
Quick LinksEntrez ID:7941; OMIM: 601690; Uniprot ID:PAFA_HUMAN; ENSEMBL ID: ENSG00000146070; HGNC ID: 9040
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult21 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal33 / 33603079
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone1 / 7165513
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta9 / 28082532
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach2 / 9661920
testis1 / 3304423
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206214_at
Cell line Expression level Expression bar
721_B_lymphoblasts7
Adipocyte6.1
AdrenalCortex7.3
Adrenalgland5.6
Amygdala6.3
Appendix7.35
AtrioventricularNode5.75
BDCA4+_DentriticCells6.25
Bonemarrow6.75
BronchialEpithelialCells6
CD105+_Endothelial7.15
CD14+_Monocytes74.35
CD19+_BCells(neg._sel.)6.4
CD33+_Myeloid17.6
CD34+7.5
CD4+_Tcells6.4
CD56+_NKCells7
CD71+_EarlyErythroid6
CD8+_Tcells5.65
CardiacMyocytes9.65
Caudatenucleus5.65
Cerebellum5.15
CerebellumPeduncles7.5
CiliaryGanglion5.2
CingulateCortex6.6
Colorectaladenocarcinoma6.25
DorsalRootGanglion5.4
FetalThyroid6.4
Fetalbrain6.05
Fetalliver7.45
Fetallung7.3
GlobusPallidus4.95
Heart9.55
Hypothalamus6.65
Kidney5.6
Leukemia_chronicMyelogenousK-5625.65
Leukemia_promyelocytic-HL-605.6
Leukemialymphoblastic(MOLT-4)4.8
Liver9.2
Lung6.85
Lymphnode16.25
Lymphoma_burkitts(Daudi)8.3
Lymphoma_burkitts(Raji)9.55
MedullaOblongata5.7
OccipitalLobe5.55
OlfactoryBulb4.9
Ovary4.5
Pancreas5.25
PancreaticIslet6.8
ParietalLobe7
Pituitary7.3
Placenta7.5
Pons6.2
PrefrontalCortex7.6
Prostate7.4
Salivarygland5.25
SkeletalMuscle8.75
Skin5.5
SmoothMuscle7.1
Spinalcord6.75
SubthalamicNucleus5.95
SuperiorCervicalGanglion8.7
TemporalLobe5.95
Testis5.35
TestisGermCell5
TestisIntersitial5.4
TestisLeydigCell6.55
TestisSeminiferousTubule5.35
Thalamus6.5
Thymus4.75
Thyroid18.05
Tongue6.8
Tonsil7
Trachea5.2
TrigeminalGanglion8.55
Uterus4.95
UterusCorpus6.15
WholeBlood12.25
Wholebrain5
colon6.3
pineal_day7.68
pineal_night7.56
retina7.625
small_intestine6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15867_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.39 ± 0.51
Basal Forebrain7.01 ± 0.33
Basal Part of Pons7.54 ± 0.23
Cerebellar Cortex6.75 ± 0.43
Cerebellar Nuclei7.86 ± 0.27
Claustrum7.54 ± 0.45
Epithalamus6.2 ± 0.66
Frontal Lobe7.11 ± 0.44
Globus Pallidus6.77 ± 0.26
Hypothalamus6.64 ± 0.26
Insula7.01 ± 0.33
Limbic Lobe7.08 ± 0.47
Mesencephalon7.04 ± 0.36
Myelencephalon7.08 ± 0.48
Occipital Lobe6.98 ± 0.45
Parietal Lobe7.03 ± 0.4
Pontine Tegmentum6.92 ± 0.46
Striatum7.5 ± 0.46
Subthalamus6.72 ± 0.5
Temporal Lobe6.99 ± 0.4
Thalamus7.1 ± 0.3
White Matter6.23 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pla2g7CBCerebellum78.61
100
Pla2g7CTXCerebral cortex53.58
52.81
Pla2g7HIPHippocampal region69.2
70.98
Pla2g7HPFHippocampal formation66.86
66.56
Pla2g7HYHypothalamus56.99
60.62
Pla2g7LSXLateral septal complex52.78
52.69
Pla2g7MBMidbrain62.84
64.38
Pla2g7MYMedulla70.71
82.6
Pla2g7OLFOlfactory bulb69.25
75.47
Pla2g7PPons75.9
84.83
Pla2g7PALPallidum43.19
53.34
Pla2g7RHPRetrohippocampal region62.43
60.06
Pla2g7sAMYStriatum-like amygdalar nuclei50.34
57.5
Pla2g7STRStriatum41.26
44.7
Pla2g7STRdStriatum dorsal region37.74
42.06
Pla2g7STRvStriatum ventral region39.44
35.96
Pla2g7THThalamus59.17
61.36
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00092761 16 348 363 GSVHQNFADFTFATGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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