AutismKB 2.0

Annotation Detail for RIC3


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Basic Information Top
Gene Symbol:RIC3 ( AYST720,FLJ11608,PRO1385 )
Gene Full Name: resistance to inhibitors of cholinesterase 3 homolog (C. elegans)
Band: 11p15.4
Quick LinksEntrez ID:79608; OMIM: 610509; Uniprot ID:RIC3_HUMAN; ENSEMBL ID: ENSG00000166405; HGNC ID: 30338
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst4 / 6231964
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult28 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal97 / 336030728
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain50 / 110098945
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye7 / 21105433
heart1 / 8962611
intestine1 / 2344724
kidney7 / 21177733
larynx1 / 2414541
liver1 / 2077434
lung4 / 33697411
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary2 / 10205119
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate7 / 18934536
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach1 / 9661910
testis6 / 33044218
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220282_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.4
Adipocyte4.45
AdrenalCortex5
Adrenalgland3.8
Amygdala4.75
Appendix4.7
AtrioventricularNode3.55
BDCA4+_DentriticCells4.9
Bonemarrow5.25
BronchialEpithelialCells4.4
CD105+_Endothelial4.5
CD14+_Monocytes4.75
CD19+_BCells(neg._sel.)4.85
CD33+_Myeloid5.75
CD34+5.6
CD4+_Tcells5.3
CD56+_NKCells5.3
CD71+_EarlyErythroid4.25
CD8+_Tcells5.55
CardiacMyocytes5.8
Caudatenucleus4.1
Cerebellum3.65
CerebellumPeduncles5.25
CiliaryGanglion3.55
CingulateCortex6.8
Colorectaladenocarcinoma4.55
DorsalRootGanglion3.65
FetalThyroid4.4
Fetalbrain4.55
Fetalliver4
Fetallung3.7
GlobusPallidus3.4
Heart6.1
Hypothalamus4.95
Kidney3.75
Leukemia_chronicMyelogenousK-5624.1
Leukemia_promyelocytic-HL-603.95
Leukemialymphoblastic(MOLT-4)3.65
Liver6.25
Lung4.95
Lymphnode3.9
Lymphoma_burkitts(Daudi)5.8
Lymphoma_burkitts(Raji)6.4
MedullaOblongata4.15
OccipitalLobe4.1
OlfactoryBulb3.55
Ovary3.1
Pancreas3.65
PancreaticIslet4.85
ParietalLobe4.9
Pituitary5.3
Placenta4.6
Pons4.4
PrefrontalCortex5.6
Prostate5.3
Salivarygland3.65
SkeletalMuscle6.25
Skin3.55
SmoothMuscle5.15
Spinalcord4.8
SubthalamicNucleus4.15
SuperiorCervicalGanglion5.45
TemporalLobe4.15
Testis3.9
TestisGermCell3.85
TestisIntersitial3.8
TestisLeydigCell4.5
TestisSeminiferousTubule3.85
Thalamus4.65
Thymus3.55
Thyroid5.6
Tongue4.5
Tonsil4.4
Trachea3.8
TrigeminalGanglion4.8
Uterus3.7
UterusCorpus4.1
WholeBlood4.95
Wholebrain3.9
colon4.6
pineal_day5.68
pineal_night5.66
retina5.5
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P64510
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.75 ± 0.76
Basal Forebrain4.01 ± 0.33
Basal Part of Pons3.92 ± 0.36
Cerebellar Cortex3.86 ± 0.47
Cerebellar Nuclei3.97 ± 0.45
Claustrum3.67 ± 0.58
Epithalamus4.09 ± 0.3
Frontal Lobe3.84 ± 0.43
Globus Pallidus3.61 ± 0.22
Hypothalamus3.67 ± 0.5
Insula3.82 ± 0.38
Limbic Lobe3.73 ± 0.5
Mesencephalon3.77 ± 0.48
Myelencephalon3.7 ± 0.48
Occipital Lobe3.56 ± 0.38
Parietal Lobe3.79 ± 0.41
Pontine Tegmentum3.76 ± 0.49
Striatum3.69 ± 0.48
Subthalamus3.78 ± 0.42
Temporal Lobe3.79 ± 0.49
Thalamus3.66 ± 0.49
White Matter3.63 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ric3CBCerebellum12.01
12.9
Ric3CTXCerebral cortex26.64
11.81
Ric3HIPHippocampal region13.02
11
Ric3HPFHippocampal formation11.38
8.38
Ric3HYHypothalamus4.49
1.59
Ric3LSXLateral septal complex3.07
1.1
Ric3MBMidbrain9.1
5.75
Ric3MYMedulla19.89
13.88
Ric3OLFOlfactory bulb17.55
8.98
Ric3PPons15.93
9.06
Ric3PALPallidum8.55
3.8
Ric3RHPRetrohippocampal region8.45
4.53
Ric3sAMYStriatum-like amygdalar nuclei9.19
3.85
Ric3STRStriatum7.96
3.17
Ric3STRdStriatum dorsal region8.43
3.33
Ric3STRvStriatum ventral region7.13
2.63
Ric3THThalamus10.83
4.95
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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