AutismKB 2.0

Annotation Detail for TMCO7


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Basic Information Top
Gene Symbol:TMCO7 ( FLJ12688,KIAA1746 )
Gene Full Name: transmembrane and coiled-coil domains 7
Band: 16q22.1
Quick LinksEntrez ID:79613; OMIM: NA; Uniprot ID:TMCO7_HUMAN; ENSEMBL ID: ENSG00000103047; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus6 / 56401210
neonate0 / 310970 
infant4 / 23620169
juvenile0 / 555560 
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor8 / 26384530
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal55 / 336030716
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone3 / 7165541
bone marrow1 / 4880120
brain15 / 110098913
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine7 / 23447229
kidney4 / 21177718
larynx0 / 241450 
liver5 / 20774324
lung3 / 3369748
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth3 / 6705244
muscle5 / 10771546
nerve1 / 1576863
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate6 / 18934531
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis11 / 33044233
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P256579
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.07 ± 0.76
Basal Forebrain3.61 ± 0.37
Basal Part of Pons3.88 ± 0.79
Cerebellar Cortex3.97 ± 0.57
Cerebellar Nuclei4.12 ± 0.6
Claustrum3.69 ± 0.7
Epithalamus3.8 ± 0.51
Frontal Lobe4.02 ± 0.53
Globus Pallidus4.1 ± 0.46
Hypothalamus3.97 ± 0.5
Insula4.18 ± 0.47
Limbic Lobe3.87 ± 0.48
Mesencephalon3.95 ± 0.59
Myelencephalon3.92 ± 0.58
Occipital Lobe3.77 ± 0.57
Parietal Lobe3.87 ± 0.49
Pontine Tegmentum3.95 ± 0.55
Striatum3.83 ± 0.76
Subthalamus4.26 ± 0.26
Temporal Lobe4.06 ± 0.48
Thalamus3.85 ± 0.49
White Matter4.06 ± 0.53
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AW413431CBCerebellum8.04
10.17
AW413431CTXCerebral cortex3.99
3.05
AW413431HIPHippocampal region3.96
3.93
AW413431HPFHippocampal formation2.87
2.62
AW413431HYHypothalamus1.53
1.1
AW413431LSXLateral septal complex0.8
0.56
AW413431MBMidbrain4.04
3.84
AW413431MYMedulla7.81
8.04
AW413431OLFOlfactory bulb4.7
4.41
AW413431PPons5.07
5.95
AW413431PALPallidum2.03
1.63
AW413431RHPRetrohippocampal region0.88
0.65
AW413431sAMYStriatum-like amygdalar nuclei1.12
1.34
AW413431STRStriatum1.64
1.3
AW413431STRdStriatum dorsal region1.63
1.34
AW413431STRvStriatum ventral region2.3
1.49
AW413431THThalamus5.74
4.86
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018