AutismKB 2.0

Annotation Detail for FAT4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:FAT4 ( CDHF14,CDHR11,FAT-J,FATJ,FLJ23056,FLJ77878,NBLA00548 )
Gene Full Name: FAT tumor suppressor homolog 4 (Drosophila)
Band: 4q28.1
Quick LinksEntrez ID:79633; OMIM: 612411; Uniprot ID:FAT4_HUMAN; ENSEMBL ID: ENSG00000196159; HGNC ID: 23109
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus23 / 56401240
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult20 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal57 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain14 / 110098912
cervix0 / 481710 
connective tissue1 / 1492556
ear1 / 1621261
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye4 / 21105418
heart1 / 8962611
intestine2 / 2344728
kidney2 / 2117779
larynx0 / 241450 
liver1 / 2077434
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate2 / 18934510
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach1 / 9661910
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219427_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.35
Adipocyte7.25
AdrenalCortex7.5
Adrenalgland5.8
Amygdala7.85
Appendix9.25
AtrioventricularNode7.7
BDCA4+_DentriticCells6.65
Bonemarrow7.25
BronchialEpithelialCells6.9
CD105+_Endothelial6.7
CD14+_Monocytes7.3
CD19+_BCells(neg._sel.)6.9
CD33+_Myeloid8.65
CD34+8.1
CD4+_Tcells6.9
CD56+_NKCells7.65
CD71+_EarlyErythroid6.45
CD8+_Tcells5.95
CardiacMyocytes10.15
Caudatenucleus6.1
Cerebellum5.55
CerebellumPeduncles7.9
CiliaryGanglion6.2
CingulateCortex7.05
Colorectaladenocarcinoma6.75
DorsalRootGanglion6.9
FetalThyroid11.6
Fetalbrain23.75
Fetalliver6.05
Fetallung6.35
GlobusPallidus5.3
Heart10.6
Hypothalamus7.35
Kidney5.65
Leukemia_chronicMyelogenousK-5626.1
Leukemia_promyelocytic-HL-606
Leukemialymphoblastic(MOLT-4)5.25
Liver10.1
Lung7.65
Lymphnode5.7
Lymphoma_burkitts(Daudi)8.7
Lymphoma_burkitts(Raji)9.95
MedullaOblongata6.15
OccipitalLobe6.1
OlfactoryBulb5.45
Ovary5.15
Pancreas5.55
PancreaticIslet7.35
ParietalLobe7.35
Pituitary7.9
Placenta6.7
Pons6.65
PrefrontalCortex8.3
Prostate8.15
Salivarygland5.65
SkeletalMuscle9.7
Skin7.2
SmoothMuscle7.7
Spinalcord7.25
SubthalamicNucleus6.35
SuperiorCervicalGanglion10.9
TemporalLobe6.55
Testis5.85
TestisGermCell5.65
TestisIntersitial5.9
TestisLeydigCell7.15
TestisSeminiferousTubule5.8
Thalamus7
Thymus5.15
Thyroid14.75
Tongue7.4
Tonsil6.85
Trachea6.2
TrigeminalGanglion8.95
Uterus6.6
UterusCorpus7.05
WholeBlood7.45
Wholebrain5.4
colon6.9
pineal_day8.28
pineal_night8.02
retina8.25
small_intestine9.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P18649
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.96 ± 0.95
Basal Forebrain1.99 ± 0.47
Basal Part of Pons1.7 ± 0.45
Cerebellar Cortex1.9 ± 0.67
Cerebellar Nuclei2.27 ± 0.64
Claustrum2.66 ± 0.62
Epithalamus2.23 ± 0.58
Frontal Lobe2.08 ± 0.91
Globus Pallidus3.16 ± 0.94
Hypothalamus1.87 ± 0.55
Insula2.31 ± 0.73
Limbic Lobe2.54 ± 1.06
Mesencephalon2.55 ± 0.85
Myelencephalon2.33 ± 0.73
Occipital Lobe2.51 ± 0.73
Parietal Lobe2.14 ± 0.81
Pontine Tegmentum2.26 ± 0.72
Striatum2.29 ± 0.74
Subthalamus2.18 ± 0.79
Temporal Lobe2.34 ± 0.89
Thalamus2.04 ± 0.7
White Matter4.67 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fat4CBCerebellum1.07
1.74
Fat4CTXCerebral cortex1.13
1.33
Fat4HIPHippocampal region10.04
13.79
Fat4HPFHippocampal formation6.5
8.39
Fat4HYHypothalamus0.56
0.84
Fat4LSXLateral septal complex0.29
0.46
Fat4MBMidbrain0.9
1.49
Fat4MYMedulla0.47
0.63
Fat4OLFOlfactory bulb2.59
2.75
Fat4PPons0.48
0.74
Fat4PALPallidum0.34
0.58
Fat4RHPRetrohippocampal region0.81
0.92
Fat4sAMYStriatum-like amygdalar nuclei0.47
0.49
Fat4STRStriatum0.77
0.84
Fat4STRdStriatum dorsal region0.99
1.12
Fat4STRvStriatum ventral region0.37
0.26
Fat4THThalamus0.58
0.75
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved