AutismKB 2.0

Annotation Detail for SCRN3


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Basic Information Top
Gene Symbol:SCRN3 ( FLJ23142,MGC149597,SES3 )
Gene Full Name: secernin 3
Band: 2q31.1
Quick LinksEntrez ID:79634; OMIM: NA; Uniprot ID:SCRN3_HUMAN; ENSEMBL ID: ENSG00000144306; HGNC ID: 30382
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus19 / 56401233
neonate2 / 3109764
infant2 / 2362084
juvenile0 / 555560 
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma6 / 17475343
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor15 / 26384556
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal110 / 336030732
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder7 / 29757235
blood1 / 1234788
bone0 / 716550 
bone marrow1 / 4880120
brain60 / 110098954
cervix2 / 4817141
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine3 / 23447212
kidney8 / 21177737
larynx0 / 241450 
liver10 / 20774348
lung9 / 33697426
lymph0 / 442700 
lymph node4 / 9161043
mammary gland0 / 1532710 
mouth2 / 6705229
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas5 / 21481223
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate1 / 1893455
salivary gland3 / 20155148
skin5 / 21057423
spleen0 / 539520 
stomach2 / 9661920
testis16 / 33044248
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord2 / 13680146
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219234_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.8
Adipocyte5.95
AdrenalCortex6.8
Adrenalgland5.25
Amygdala6.25
Appendix6.85
AtrioventricularNode5.45
BDCA4+_DentriticCells6.2
Bonemarrow6.3
BronchialEpithelialCells5.85
CD105+_Endothelial6.05
CD14+_Monocytes6.45
CD19+_BCells(neg._sel.)6.3
CD33+_Myeloid7.65
CD34+7.5
CD4+_Tcells6.2
CD56+_NKCells6.9
CD71+_EarlyErythroid5.75
CD8+_Tcells5.6
CardiacMyocytes8.7
Caudatenucleus5.4
Cerebellum4.9
CerebellumPeduncles7.1
CiliaryGanglion4.9
CingulateCortex6.3
Colorectaladenocarcinoma5.95
DorsalRootGanglion5.15
FetalThyroid6.15
Fetalbrain5.95
Fetalliver5.3
Fetallung4.8
GlobusPallidus4.65
Heart8.55
Hypothalamus6.5
Kidney5.2
Leukemia_chronicMyelogenousK-5625.7
Leukemia_promyelocytic-HL-605.35
Leukemialymphoblastic(MOLT-4)4.7
Liver8.5
Lung6.45
Lymphnode5.1
Lymphoma_burkitts(Daudi)7.85
Lymphoma_burkitts(Raji)8.85
MedullaOblongata5.45
OccipitalLobe5.4
OlfactoryBulb4.75
Ovary4.25
Pancreas5
PancreaticIslet6.45
ParietalLobe6.65
Pituitary7
Placenta6.05
Pons5.85
PrefrontalCortex7.4
Prostate7
Salivarygland4.95
SkeletalMuscle7.75
Skin5.1
SmoothMuscle6.85
Spinalcord6.45
SubthalamicNucleus5.65
SuperiorCervicalGanglion8.4
TemporalLobe5.65
Testis5.15
TestisGermCell4.9
TestisIntersitial5.05
TestisLeydigCell6.15
TestisSeminiferousTubule5.2
Thalamus6.4
Thymus4.55
Thyroid7.45
Tongue6.3
Tonsil5.95
Trachea5
TrigeminalGanglion6.65
Uterus4.8
UterusCorpus5.75
WholeBlood6.5
Wholebrain4.95
colon6.05
pineal_day9.28
pineal_night8.44
retina7.325
small_intestine5.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P17021
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.91 ± 0.65
Basal Forebrain6.17 ± 0.23
Basal Part of Pons6.34 ± 0.38
Cerebellar Cortex5.92 ± 0.28
Cerebellar Nuclei6.63 ± 0.32
Claustrum5.58 ± 0.78
Epithalamus6.35 ± 0.38
Frontal Lobe6.43 ± 0.32
Globus Pallidus6.68 ± 0.32
Hypothalamus6.44 ± 0.29
Insula6.41 ± 0.44
Limbic Lobe5.95 ± 0.6
Mesencephalon6.11 ± 0.52
Myelencephalon6.14 ± 0.55
Occipital Lobe5.77 ± 0.62
Parietal Lobe6.22 ± 0.44
Pontine Tegmentum6.16 ± 0.46
Striatum6.01 ± 0.36
Subthalamus6.69 ± 0.4
Temporal Lobe6.26 ± 0.37
Thalamus6.21 ± 0.49
White Matter6.77 ± 0.23
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00499322 14 353 366 HQQALEVVNNNEEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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