AutismKB 2.0

Annotation Detail for AIMP2


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Basic Information Top
Gene Symbol:AIMP2 ( JTV-1,JTV1,P38 )
Gene Full Name: aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Band: 7p22.1
Quick LinksEntrez ID:7965; OMIM: 600859; Uniprot ID:AIMP2_HUMAN; ENSEMBL ID: ENSG00000106305; HGNC ID: 20609
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst5 / 6231980
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult90 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor4 / 34366116
chondrosarcoma7 / 8282384
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor11 / 26384541
glioma9 / 10688384
head and neck tumor3 / 13630222
kidney tumor4 / 6895958
leukemia5 / 9584252
liver tumor6 / 9635962
lung tumor7 / 10312767
lymphoma12 / 71755167
non-neoplasia4 / 9725041
normal145 / 336030743
ovarian tumor10 / 76682130
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor15 / 124949120
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites2 / 4001549
bladder1 / 2975733
blood4 / 12347832
bone6 / 7165583
bone marrow2 / 4880140
brain38 / 110098934
cervix4 / 4817183
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye20 / 21105494
heart4 / 8962644
intestine19 / 23447281
kidney7 / 21177733
larynx0 / 241450 
liver10 / 20774348
lung24 / 33697471
lymph8 / 44270180
lymph node10 / 91610109
mammary gland4 / 15327126
mouth0 / 670520 
muscle9 / 10771583
nerve0 / 157680 
ovary12 / 102051117
pancreas11 / 21481251
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate9 / 18934547
salivary gland3 / 20155148
skin28 / 210574132
spleen1 / 5395218
stomach4 / 9661941
testis13 / 33044239
thymus0 / 811310 
thyroid2 / 4747342
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord1 / 1368073
uterus11 / 23287847
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202138_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts567.65
Adipocyte112.6
AdrenalCortex22.75
Adrenalgland80.6
Amygdala83.95
Appendix26.2
AtrioventricularNode11.75
BDCA4+_DentriticCells136.65
Bonemarrow80.95
BronchialEpithelialCells428.25
CD105+_Endothelial336.05
CD14+_Monocytes195.3
CD19+_BCells(neg._sel.)77.1
CD33+_Myeloid132.45
CD34+341.65
CD4+_Tcells35.95
CD56+_NKCells169.6
CD71+_EarlyErythroid71.8
CD8+_Tcells48.65
CardiacMyocytes152.4
Caudatenucleus59.45
Cerebellum53
CerebellumPeduncles39.45
CiliaryGanglion20
CingulateCortex26.55
Colorectaladenocarcinoma421.8
DorsalRootGanglion19
FetalThyroid82.15
Fetalbrain54.85
Fetalliver87.7
Fetallung59.95
GlobusPallidus19.7
Heart461.4
Hypothalamus100.9
Kidney87
Leukemia_chronicMyelogenousK-562254.6
Leukemia_promyelocytic-HL-60345.7
Leukemialymphoblastic(MOLT-4)46.75
Liver353.15
Lung301.75
Lymphnode30.9
Lymphoma_burkitts(Daudi)670.5
Lymphoma_burkitts(Raji)550.15
MedullaOblongata31.4
OccipitalLobe45.15
OlfactoryBulb19
Ovary11.3
Pancreas63.3
PancreaticIslet83.65
ParietalLobe69.85
Pituitary42.55
Placenta113.25
Pons36.1
PrefrontalCortex34.45
Prostate159.75
Salivarygland41.85
SkeletalMuscle114
Skin19.9
SmoothMuscle179.2
Spinalcord81.3
SubthalamicNucleus25.15
SuperiorCervicalGanglion67.95
TemporalLobe19.85
Testis723.6
TestisGermCell245.7
TestisIntersitial380.7
TestisLeydigCell260.95
TestisSeminiferousTubule181.1
Thalamus61.55
Thymus88.55
Thyroid186.35
Tongue103.05
Tonsil72.25
Trachea42.35
TrigeminalGanglion37.8
Uterus50.5
UterusCorpus37.75
WholeBlood54.15
Wholebrain139.95
colon239.75
pineal_day89.6
pineal_night96.24
retina100.6
small_intestine290
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7447_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.01 ± 0.33
Basal Forebrain4.85 ± 0.29
Basal Part of Pons5.22 ± 0.21
Cerebellar Cortex4.86 ± 0.43
Cerebellar Nuclei4.99 ± 0.26
Claustrum4.86 ± 0.54
Epithalamus4.73 ± 0.39
Frontal Lobe5.06 ± 0.36
Globus Pallidus5 ± 0.24
Hypothalamus4.73 ± 0.45
Insula4.89 ± 0.35
Limbic Lobe4.99 ± 0.37
Mesencephalon4.87 ± 0.41
Myelencephalon4.98 ± 0.36
Occipital Lobe4.73 ± 0.41
Parietal Lobe4.96 ± 0.33
Pontine Tegmentum4.86 ± 0.34
Striatum5 ± 0.29
Subthalamus4.58 ± 0.33
Temporal Lobe5.01 ± 0.34
Thalamus4.99 ± 0.29
White Matter5.04 ± 0.4
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
AIMP2_HUMAN_120 20 120 139 DIVINANPASPPLSLLVLHR PRIDE
AIMP2_HUMAN_128 13 128 140 PASPPLSLLVLHR PRIDE
AIMP2_HUMAN_2 16 2 17 PMYQVKPYHGGGAPLR PRIDE
AIMP2_HUMAN_3 15 3 17 MYQVKPYHGGGAPLR PRIDE
AIMP2_HUMAN_305 16 305 320 SCENLAPFNTALKLLK PRIDE
PAp00002579 17 199 215 FSIQTMCPIEGEGNIAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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