AutismKB 2.0

Annotation Detail for ARHGAP10


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Basic Information Top
Gene Symbol:ARHGAP10 ( FLJ20896,FLJ41791,GRAF2,PS-GAP,PSGAP )
Gene Full Name: Rho GTPase activating protein 10
Band: 4q31.23
Quick LinksEntrez ID:79658; OMIM: 609746; Uniprot ID:RHG10_HUMAN; ENSEMBL ID: ENSG00000071205; HGNC ID: 26099
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor5 / 6895972
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal46 / 336030713
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye4 / 21105418
heart1 / 8962611
intestine5 / 23447221
kidney9 / 21177742
larynx0 / 241450 
liver3 / 20774314
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth2 / 6705229
muscle3 / 10771527
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate2 / 18934510
salivary gland0 / 201550 
skin8 / 21057437
spleen1 / 5395218
stomach1 / 9661910
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219431_at
Cell line Expression level Expression bar
721_B_lymphoblasts16.15
Adipocyte8.15
AdrenalCortex5.2
Adrenalgland4.25
Amygdala5.4
Appendix5.1
AtrioventricularNode3.8
BDCA4+_DentriticCells5.75
Bonemarrow4.95
BronchialEpithelialCells9.5
CD105+_Endothelial5.25
CD14+_Monocytes5.5
CD19+_BCells(neg._sel.)5.55
CD33+_Myeloid6.7
CD34+9.05
CD4+_Tcells8.75
CD56+_NKCells9.65
CD71+_EarlyErythroid4.8
CD8+_Tcells10.15
CardiacMyocytes6.4
Caudatenucleus4.5
Cerebellum4
CerebellumPeduncles5.65
CiliaryGanglion3.5
CingulateCortex5.2
Colorectaladenocarcinoma6.7
DorsalRootGanglion3.8
FetalThyroid4.9
Fetalbrain5
Fetalliver4.55
Fetallung4.35
GlobusPallidus3.6
Heart6.45
Hypothalamus5.6
Kidney3.9
Leukemia_chronicMyelogenousK-5624.6
Leukemia_promyelocytic-HL-604.7
Leukemialymphoblastic(MOLT-4)4
Liver9
Lung11.55
Lymphnode4.45
Lymphoma_burkitts(Daudi)6.5
Lymphoma_burkitts(Raji)7.65
MedullaOblongata4.6
OccipitalLobe4.55
OlfactoryBulb4.45
Ovary3.7
Pancreas4.1
PancreaticIslet5.5
ParietalLobe4.95
Pituitary5.65
Placenta5.1
Pons4.85
PrefrontalCortex6.45
Prostate6.1
Salivarygland4.05
SkeletalMuscle5.6
Skin4.05
SmoothMuscle6.05
Spinalcord5.45
SubthalamicNucleus4.35
SuperiorCervicalGanglion5.65
TemporalLobe4.6
Testis4.4
TestisGermCell6.15
TestisIntersitial4.3
TestisLeydigCell5.05
TestisSeminiferousTubule4.4
Thalamus5.2
Thymus4
Thyroid6.5
Tongue5.15
Tonsil4.9
Trachea4.25
TrigeminalGanglion5
Uterus8.4
UterusCorpus4.3
WholeBlood5.65
Wholebrain4.35
colon7.1
pineal_day6.32
pineal_night6.24
retina6.25
small_intestine4.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9556_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.38 ± 1.09
Basal Forebrain1.91 ± 0.22
Basal Part of Pons1.58 ± 0.39
Cerebellar Cortex1.73 ± 0.65
Cerebellar Nuclei2.25 ± 0.73
Claustrum2.57 ± 0.66
Epithalamus1.58 ± 0.63
Frontal Lobe1.77 ± 0.62
Globus Pallidus2.43 ± 0.37
Hypothalamus1.93 ± 0.69
Insula1.65 ± 0.42
Limbic Lobe1.92 ± 0.69
Mesencephalon2.07 ± 0.69
Myelencephalon1.95 ± 0.67
Occipital Lobe1.9 ± 0.65
Parietal Lobe1.99 ± 0.68
Pontine Tegmentum1.98 ± 0.68
Striatum1.94 ± 0.45
Subthalamus2.03 ± 0.61
Temporal Lobe1.92 ± 0.8
Thalamus1.88 ± 0.59
White Matter2.86 ± 0.97
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Arhgap10CBCerebellum1.5
2.5
Arhgap10CTXCerebral cortex3.16
2.37
Arhgap10HIPHippocampal region0.56
0.72
Arhgap10HPFHippocampal formation0.66
0.78
Arhgap10HYHypothalamus0.19
0.23
Arhgap10LSXLateral septal complex6.36
5.66
Arhgap10MBMidbrain1.17
2.21
Arhgap10MYMedulla1.54
2.4
Arhgap10OLFOlfactory bulb5.43
3.99
Arhgap10PPons0.95
1.34
Arhgap10PALPallidum0.77
0.62
Arhgap10RHPRetrohippocampal region0.81
0.85
Arhgap10sAMYStriatum-like amygdalar nuclei2.02
2.19
Arhgap10STRStriatum5.11
3.4
Arhgap10STRdStriatum dorsal region3.92
2.48
Arhgap10STRvStriatum ventral region12.71
7.37
Arhgap10THThalamus0.49
0.48
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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