AutismKB 2.0

Annotation Detail for HSPBAP1


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Basic Information Top
Gene Symbol:HSPBAP1 ( FLJ22623,FLJ39386,PASS1 )
Gene Full Name: HSPB (heat shock 27kDa) associated protein 1
Band: 3q21.1
Quick LinksEntrez ID:79663; OMIM: 608263; Uniprot ID:HBAP1_HUMAN; ENSEMBL ID: ENSG00000169087; HGNC ID: 16389
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult56 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal59 / 336030717
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone7 / 7165597
bone marrow3 / 4880161
brain10 / 11009899
cervix4 / 4817183
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine1 / 2344724
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node2 / 9161021
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta19 / 28082567
prostate1 / 1893455
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach1 / 9661910
testis16 / 33044248
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219284_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.75
Adipocyte7.1
AdrenalCortex8.8
Adrenalgland6.3
Amygdala7.35
Appendix7.95
AtrioventricularNode5.6
BDCA4+_DentriticCells11.25
Bonemarrow7.45
BronchialEpithelialCells7.1
CD105+_Endothelial7.75
CD14+_Monocytes42.15
CD19+_BCells(neg._sel.)15.05
CD33+_Myeloid49.1
CD34+24.85
CD4+_Tcells21.1
CD56+_NKCells19.65
CD71+_EarlyErythroid6.9
CD8+_Tcells28.05
CardiacMyocytes9.45
Caudatenucleus6.5
Cerebellum5.95
CerebellumPeduncles8.25
CiliaryGanglion5.1
CingulateCortex7.65
Colorectaladenocarcinoma7.2
DorsalRootGanglion6.25
FetalThyroid7.4
Fetalbrain7.05
Fetalliver6.5
Fetallung5.65
GlobusPallidus5.65
Heart9.45
Hypothalamus8.7
Kidney5.95
Leukemia_chronicMyelogenousK-5626.55
Leukemia_promyelocytic-HL-606.55
Leukemialymphoblastic(MOLT-4)6.15
Liver10.15
Lung8
Lymphnode6.7
Lymphoma_burkitts(Daudi)9.45
Lymphoma_burkitts(Raji)10.5
MedullaOblongata6.7
OccipitalLobe6.55
OlfactoryBulb7.1
Ovary5.15
Pancreas8
PancreaticIslet8.25
ParietalLobe7.8
Pituitary8.6
Placenta12.15
Pons7.35
PrefrontalCortex9.2
Prostate8.4
Salivarygland6.15
SkeletalMuscle10.65
Skin6
SmoothMuscle8.2
Spinalcord7.95
SubthalamicNucleus6.9
SuperiorCervicalGanglion10.75
TemporalLobe6.95
Testis7.65
TestisGermCell9
TestisIntersitial10.3
TestisLeydigCell9.95
TestisSeminiferousTubule6.45
Thalamus7.4
Thymus5.7
Thyroid9.3
Tongue7.3
Tonsil7.35
Trachea6
TrigeminalGanglion8.8
Uterus6.15
UterusCorpus8.05
WholeBlood34.55
Wholebrain5.8
colon7.3
pineal_day39.12
pineal_night23.4
retina9.225
small_intestine6.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_552_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.42 ± 0.3
Basal Forebrain5.35 ± 0.2
Basal Part of Pons5.57 ± 0.3
Cerebellar Cortex5.34 ± 0.27
Cerebellar Nuclei5.29 ± 0.44
Claustrum5.67 ± 0.67
Epithalamus5.59 ± 0.42
Frontal Lobe5.13 ± 0.38
Globus Pallidus5.78 ± 0.33
Hypothalamus5.27 ± 0.28
Insula5.11 ± 0.35
Limbic Lobe5.38 ± 0.45
Mesencephalon5.4 ± 0.37
Myelencephalon5.35 ± 0.4
Occipital Lobe5.72 ± 0.41
Parietal Lobe5.4 ± 0.36
Pontine Tegmentum5.22 ± 0.45
Striatum5.61 ± 0.39
Subthalamus5.56 ± 0.57
Temporal Lobe5.24 ± 0.37
Thalamus5.17 ± 0.42
White Matter6.38 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hspbap1CBCerebellum5.32
5.94
Hspbap1CTXCerebral cortex2.86
2.81
Hspbap1HIPHippocampal region5.31
5.01
Hspbap1HPFHippocampal formation4.5
3.99
Hspbap1HYHypothalamus0.32
0.32
Hspbap1LSXLateral septal complex0.34
0.29
Hspbap1MBMidbrain1.4
1.7
Hspbap1MYMedulla3.06
3.66
Hspbap1OLFOlfactory bulb5.45
4.88
Hspbap1PPons2.19
2.83
Hspbap1PALPallidum0.52
0.42
Hspbap1RHPRetrohippocampal region3.19
2.63
Hspbap1sAMYStriatum-like amygdalar nuclei0.36
0.33
Hspbap1STRStriatum0.78
0.71
Hspbap1STRdStriatum dorsal region0.95
0.92
Hspbap1STRvStriatum ventral region0.48
0.27
Hspbap1THThalamus1.56
1.89
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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