AutismKB 2.0

Annotation Detail for ZCCHC6


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Basic Information Top
Gene Symbol:ZCCHC6 ( DKFZp666B142,DKFZp686C11112,DKFZp686F119,DKFZp686I1269,PAPD6 )
Gene Full Name: zinc finger, CCHC domain containing 6
Band: 9q21.33
Quick LinksEntrez ID:79670; OMIM: NA; Uniprot ID:TUT7_HUMAN; ENSEMBL ID: ENSG00000083223; HGNC ID: 25817
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus30 / 56401253
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult88 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor9 / 9417895
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor8 / 26384530
glioma0 / 1068830 
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal141 / 336030741
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood9 / 12347872
bone3 / 7165541
bone marrow0 / 488010 
brain19 / 110098917
cervix1 / 4817120
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye8 / 21105437
heart1 / 8962611
intestine14 / 23447259
kidney4 / 21177718
larynx0 / 241450 
liver8 / 20774338
lung12 / 33697435
lymph0 / 442700 
lymph node8 / 9161087
mammary gland17 / 153271110
mouth2 / 6705229
muscle5 / 10771546
nerve2 / 15768126
ovary1 / 1020519
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland3 / 16585180
placenta9 / 28082532
prostate6 / 18934531
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach8 / 9661982
testis8 / 33044224
thymus4 / 8113149
thyroid2 / 4747342
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus3 / 23287812
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220933_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts41.7
Adipocyte8.6
AdrenalCortex7.2
Adrenalgland5.8
Amygdala7.5
Appendix7
AtrioventricularNode5.5
BDCA4+_DentriticCells59.65
Bonemarrow6.9
BronchialEpithelialCells12.9
CD105+_Endothelial17.55
CD14+_Monocytes119.9
CD19+_BCells(neg._sel.)53.7
CD33+_Myeloid166.4
CD34+40.95
CD4+_Tcells65.35
CD56+_NKCells147.1
CD71+_EarlyErythroid35.6
CD8+_Tcells68
CardiacMyocytes8.5
Caudatenucleus6.3
Cerebellum5.7
CerebellumPeduncles7.9
CiliaryGanglion4.85
CingulateCortex7.2
Colorectaladenocarcinoma7.1
DorsalRootGanglion5.25
FetalThyroid6.85
Fetalbrain7
Fetalliver6.05
Fetallung7.25
GlobusPallidus5.1
Heart7.5
Hypothalamus7.7
Kidney4.45
Leukemia_chronicMyelogenousK-5626.4
Leukemia_promyelocytic-HL-608.65
Leukemialymphoblastic(MOLT-4)6.3
Liver9.15
Lung7.45
Lymphnode24.5
Lymphoma_burkitts(Daudi)9.25
Lymphoma_burkitts(Raji)21.05
MedullaOblongata6.5
OccipitalLobe6.35
OlfactoryBulb5.9
Ovary4.65
Pancreas10.75
PancreaticIslet9.45
ParietalLobe7.3
Pituitary8.25
Placenta7.4
Pons6.5
PrefrontalCortex9
Prostate17
Salivarygland6.15
SkeletalMuscle7.9
Skin6.65
SmoothMuscle8.55
Spinalcord7.55
SubthalamicNucleus6.3
SuperiorCervicalGanglion7.8
TemporalLobe6.35
Testis5.7
TestisGermCell9.35
TestisIntersitial6.6
TestisLeydigCell6.9
TestisSeminiferousTubule6.05
Thalamus7.05
Thymus5.6
Thyroid9.65
Tongue8.3
Tonsil26.1
Trachea5.9
TrigeminalGanglion6.9
Uterus7.1
UterusCorpus6.55
WholeBlood347.95
Wholebrain5.45
colon7.15
pineal_day9.64
pineal_night10.26
retina8.25
small_intestine6.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P68275
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.52 ± 0.39
Basal Forebrain6.55 ± 0.25
Basal Part of Pons6.25 ± 0.5
Cerebellar Cortex6.29 ± 0.3
Cerebellar Nuclei6.74 ± 0.44
Claustrum6.96 ± 0.44
Epithalamus6.33 ± 0.35
Frontal Lobe6.3 ± 0.33
Globus Pallidus7.07 ± 0.17
Hypothalamus6.16 ± 0.25
Insula6.23 ± 0.27
Limbic Lobe6.47 ± 0.37
Mesencephalon6.53 ± 0.32
Myelencephalon6.53 ± 0.38
Occipital Lobe6.86 ± 0.38
Parietal Lobe6.57 ± 0.3
Pontine Tegmentum6.48 ± 0.43
Striatum6.73 ± 0.33
Subthalamus6.52 ± 0.25
Temporal Lobe6.41 ± 0.32
Thalamus6.55 ± 0.26
White Matter7.64 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zcchc6CBCerebellum15.63
37.13
Zcchc6CTXCerebral cortex41.59
34.12
Zcchc6HIPHippocampal region30.9
39.21
Zcchc6HPFHippocampal formation32.17
36.47
Zcchc6HYHypothalamus4.4
5.03
Zcchc6LSXLateral septal complex8.16
6.27
Zcchc6MBMidbrain2.55
3.7
Zcchc6MYMedulla2.05
2.95
Zcchc6OLFOlfactory bulb25.2
22.8
Zcchc6PPons1.9
2.96
Zcchc6PALPallidum12.73
13
Zcchc6RHPRetrohippocampal region34.28
32.86
Zcchc6sAMYStriatum-like amygdalar nuclei12.17
11.38
Zcchc6STRStriatum15.35
13.1
Zcchc6STRdStriatum dorsal region15.98
13.83
Zcchc6STRvStriatum ventral region17.98
14.17
Zcchc6THThalamus11.83
11.09
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00027907 18 515 532 SSLLKPLNAITCISEHSK Peptide Atlas
TUT7_HUMAN_1372 8 1372 1379 QEDALNQR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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