AutismKB 2.0

Annotation Detail for NLRX1


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Basic Information Top
Gene Symbol:NLRX1 ( CLR11.3,DLNB26,FLJ21478,MGC131937,MGC21025,NOD26,NOD5,NOD9 )
Gene Full Name: NLR family member X1
Band: 11q23.3
Quick LinksEntrez ID:79671; OMIM: 611947; Uniprot ID:NLRX1_HUMAN; ENSEMBL ID: ENSG00000160703; HGNC ID: 29890
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor10 / 11424687
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor12 / 26384545
glioma2 / 10688318
head and neck tumor19 / 136302139
kidney tumor2 / 6895929
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal51 / 336030715
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone5 / 7165569
bone marrow2 / 4880140
brain14 / 110098912
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine10 / 23447242
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node4 / 9161043
mammary gland3 / 15327119
mouth19 / 67052283
muscle2 / 10771518
nerve1 / 1576863
ovary3 / 10205129
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate4 / 18934521
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach4 / 9661941
testis10 / 33044230
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219680_at
Cell line Expression level Expression bar
721_B_lymphoblasts81.95
Adipocyte49.4
AdrenalCortex56.8
Adrenalgland42.3
Amygdala50.75
Appendix50.1
AtrioventricularNode39.35
BDCA4+_DentriticCells53.65
Bonemarrow77.05
BronchialEpithelialCells53.3
CD105+_Endothelial49.5
CD14+_Monocytes53.3
CD19+_BCells(neg._sel.)47.95
CD33+_Myeloid64.2
CD34+63.1
CD4+_Tcells53.95
CD56+_NKCells59.85
CD71+_EarlyErythroid45.85
CD8+_Tcells47.05
CardiacMyocytes61.8
Caudatenucleus44.65
Cerebellum40.1
CerebellumPeduncles63.4
CiliaryGanglion36.9
CingulateCortex50.45
Colorectaladenocarcinoma49.5
DorsalRootGanglion38.4
FetalThyroid51.65
Fetalbrain48.2
Fetalliver42.9
Fetallung41.2
GlobusPallidus36.35
Heart154.8
Hypothalamus54
Kidney41.2
Leukemia_chronicMyelogenousK-56243.2
Leukemia_promyelocytic-HL-6043.3
Leukemialymphoblastic(MOLT-4)40.15
Liver66.85
Lung85.4
Lymphnode42.85
Lymphoma_burkitts(Daudi)63.35
Lymphoma_burkitts(Raji)69.1
MedullaOblongata45.1
OccipitalLobe43.65
OlfactoryBulb52.2
Ovary37.15
Pancreas41.7
PancreaticIslet69.25
ParietalLobe52.9
Pituitary58.1
Placenta50.95
Pons47.3
PrefrontalCortex61.65
Prostate79.75
Salivarygland39.1
SkeletalMuscle91.85
Skin42.7
SmoothMuscle63
Spinalcord53.65
SubthalamicNucleus44.95
SuperiorCervicalGanglion55.55
TemporalLobe46.65
Testis42.75
TestisGermCell41.7
TestisIntersitial41.55
TestisLeydigCell53.4
TestisSeminiferousTubule42.75
Thalamus50.05
Thymus48.65
Thyroid125.85
Tongue94.45
Tonsil55.4
Trachea42.95
TrigeminalGanglion53.95
Uterus41.05
UterusCorpus58.75
WholeBlood58.7
Wholebrain40.35
colon48.55
pineal_day58.4
pineal_night54.16
retina63.55
small_intestine45.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6218_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.94 ± 0.65
Basal Forebrain3.97 ± 0.42
Basal Part of Pons3.44 ± 0.49
Cerebellar Cortex3.93 ± 0.42
Cerebellar Nuclei3.91 ± 0.49
Claustrum4.06 ± 0.58
Epithalamus3.94 ± 0.31
Frontal Lobe3.77 ± 0.49
Globus Pallidus3.95 ± 0.53
Hypothalamus3.76 ± 0.53
Insula3.46 ± 0.5
Limbic Lobe3.69 ± 0.52
Mesencephalon3.85 ± 0.6
Myelencephalon3.83 ± 0.52
Occipital Lobe3.78 ± 0.63
Parietal Lobe3.91 ± 0.54
Pontine Tegmentum3.82 ± 0.53
Striatum3.8 ± 0.37
Subthalamus3.84 ± 0.46
Temporal Lobe3.78 ± 0.59
Thalamus3.7 ± 0.5
White Matter3.93 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
BC034204CBCerebellum2.39
2.96
BC034204CTXCerebral cortex5.76
3.95
BC034204HIPHippocampal region7.93
7.59
BC034204HPFHippocampal formation7.19
6.44
BC034204HYHypothalamus25.77
20.88
BC034204LSXLateral septal complex1.1
0.79
BC034204MBMidbrain2.77
3.81
BC034204MYMedulla9.34
12.56
BC034204OLFOlfactory bulb15.61
11.74
BC034204PPons16.84
21.29
BC034204PALPallidum5.64
5.1
BC034204RHPRetrohippocampal region5.45
4.51
BC034204sAMYStriatum-like amygdalar nuclei11.68
8.29
BC034204STRStriatum4.46
3.21
BC034204STRdStriatum dorsal region1.36
0.91
BC034204STRvStriatum ventral region13.21
9.12
BC034204THThalamus3.21
2.72
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00518241 18 99 116 QFGPTFALDTVHVDPVIR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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