AutismKB 2.0

Annotation Detail for PRKRIP1


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Basic Information Top
Gene Symbol:PRKRIP1 ( C114,FLJ13902,FLJ40957,KRBOX3 )
Gene Full Name: PRKR interacting protein 1 (IL11 inducible)
Band: 7q22.1
Quick LinksEntrez ID:79706; OMIM: NA; Uniprot ID:PKRI1_HUMAN; ENSEMBL ID: ENSG00000128563; HGNC ID: 21894
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult52 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma10 / 71755139
non-neoplasia0 / 972500 
normal48 / 336030714
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor5 / 12494940
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain16 / 110098914
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine6 / 23447225
kidney5 / 21177723
larynx1 / 2414541
liver4 / 20774319
lung3 / 3369748
lymph8 / 44270180
lymph node6 / 9161065
mammary gland1 / 1532716
mouth4 / 6705259
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate2 / 18934510
salivary gland0 / 201550 
skin5 / 21057423
spleen2 / 5395237
stomach2 / 9661920
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218378_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts18.85
Adipocyte14.1
AdrenalCortex14.35
Adrenalgland11.55
Amygdala14.55
Appendix13.95
AtrioventricularNode8.85
BDCA4+_DentriticCells19.15
Bonemarrow13.8
BronchialEpithelialCells13.8
CD105+_Endothelial14.65
CD14+_Monocytes15.3
CD19+_BCells(neg._sel.)23.25
CD33+_Myeloid19.05
CD34+19.2
CD4+_Tcells28.7
CD56+_NKCells23.75
CD71+_EarlyErythroid12.75
CD8+_Tcells33.2
CardiacMyocytes18.05
Caudatenucleus12.45
Cerebellum15.05
CerebellumPeduncles19.25
CiliaryGanglion9.8
CingulateCortex14.2
Colorectaladenocarcinoma38.15
DorsalRootGanglion10.55
FetalThyroid15.75
Fetalbrain22.45
Fetalliver11.9
Fetallung12.05
GlobusPallidus9.9
Heart17.95
Hypothalamus21.35
Kidney10.05
Leukemia_chronicMyelogenousK-56213.8
Leukemia_promyelocytic-HL-6013.7
Leukemialymphoblastic(MOLT-4)24.35
Liver18.55
Lung19.75
Lymphnode18.95
Lymphoma_burkitts(Daudi)22.55
Lymphoma_burkitts(Raji)21.25
MedullaOblongata13.25
OccipitalLobe11.1
OlfactoryBulb10.8
Ovary8.85
Pancreas10.45
PancreaticIslet15.3
ParietalLobe15.15
Pituitary17.15
Placenta15.35
Pons13.45
PrefrontalCortex16.6
Prostate18
Salivarygland11.2
SkeletalMuscle16.05
Skin10.2
SmoothMuscle14.7
Spinalcord17.85
SubthalamicNucleus12.85
SuperiorCervicalGanglion15.95
TemporalLobe12.55
Testis12.75
TestisGermCell12.45
TestisIntersitial12.05
TestisLeydigCell14.25
TestisSeminiferousTubule13.25
Thalamus14.4
Thymus17
Thyroid24.05
Tongue13.7
Tonsil13.95
Trachea12.1
TrigeminalGanglion12.9
Uterus14.9
UterusCorpus12.8
WholeBlood15.8
Wholebrain14.35
colon13.35
pineal_day26.74
pineal_night23.24
retina20.4
small_intestine11.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P82316
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.93 ± 0.19
Basal Forebrain7.76 ± 0.11
Basal Part of Pons7.52 ± 0.16
Cerebellar Cortex7.83 ± 0.17
Cerebellar Nuclei7.42 ± 0.12
Claustrum7.86 ± 0.28
Epithalamus7.47 ± 0.17
Frontal Lobe7.49 ± 0.25
Globus Pallidus8.02 ± 0.21
Hypothalamus7.64 ± 0.29
Insula7.58 ± 0.25
Limbic Lobe7.75 ± 0.33
Mesencephalon7.67 ± 0.27
Myelencephalon7.63 ± 0.27
Occipital Lobe7.8 ± 0.29
Parietal Lobe7.65 ± 0.3
Pontine Tegmentum7.59 ± 0.3
Striatum7.78 ± 0.36
Subthalamus7.45 ± 0.25
Temporal Lobe7.63 ± 0.25
Thalamus7.56 ± 0.24
White Matter8.36 ± 0.14
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prkrip1CBCerebellum36.52
54.95
Prkrip1CTXCerebral cortex100
100
Prkrip1HIPHippocampal region70
100
Prkrip1HPFHippocampal formation92.9
100
Prkrip1HYHypothalamus67.42
60.42
Prkrip1LSXLateral septal complex71.64
59.04
Prkrip1MBMidbrain64.1
65.12
Prkrip1MYMedulla45.67
54.96
Prkrip1OLFOlfactory bulb92.61
89.38
Prkrip1PPons56.3
67.09
Prkrip1PALPallidum53.45
54.52
Prkrip1RHPRetrohippocampal region100
100
Prkrip1sAMYStriatum-like amygdalar nuclei87.72
76.13
Prkrip1STRStriatum70.88
59.4
Prkrip1STRdStriatum dorsal region70.36
59.24
Prkrip1STRvStriatum ventral region70.13
55.68
Prkrip1THThalamus82.01
76.52
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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