Annotation Detail for PPCS
Basic Information Top
| Gene Symbol: | PPCS ( FLJ11838,MGC117357,MGC138220 ) |
|---|---|
| Gene Full Name: | phosphopantothenoylcysteine synthetase |
| Band: | 1p34.2 |
| Quick Links | Entrez ID:79717; OMIM: 609853; Uniprot ID:PPCS_HUMAN; ENSEMBL ID: ENSG00000127125; HGNC ID: 25686 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.706662
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 4 / 70761 | 56 |  |
| blastocyst | 2 / 62319 | 32 |  |
| fetus | 11 / 564012 | 19 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 93 / 1939121 | 47 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 10 / 17475 | 572 |  |
| breast (mammary gland) tumor | 11 / 94178 | 116 | |
| cervical tumor | 3 / 34366 | 87 | |
| chondrosarcoma | 6 / 82823 | 72 | |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 12 / 119369 | 100 | |
| germ cell tumor | 12 / 263845 | 45 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 6 / 95842 | 62 | |
| liver tumor | 4 / 96359 | 41 | |
| lung tumor | 3 / 103127 | 29 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 |  |
| normal | 109 / 3360307 | 32 | |
| ovarian tumor | 5 / 76682 | 65 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 6 / 102680 | 58 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 4 / 124949 | 32 | |
| soft tissue/muscle tissue tumor | 9 / 125191 | 71 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 5 / 40015 | 124 | |
| bladder | 7 / 29757 | 235 | |
| blood | 6 / 123478 | 48 | |
| bone | 5 / 71655 | 69 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 25 / 1100989 | 22 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 9 / 149255 | 60 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 9 / 215722 | 41 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 7 / 211054 | 33 | |
| heart | 1 / 89626 | 11 | |
| intestine | 13 / 234472 | 55 | |
| kidney | 9 / 211777 | 42 | |
| larynx | 0 / 24145 | 0 | |
| liver | 8 / 207743 | 38 | |
| lung | 12 / 336974 | 35 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 5 / 91610 | 54 | |
| mammary gland | 15 / 153271 | 97 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 7 / 102051 | 68 | |
| pancreas | 10 / 214812 | 46 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 3 / 41328 | 72 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 16 / 280825 | 56 | |
| prostate | 10 / 189345 | 52 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 5 / 210574 | 23 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 6 / 96619 | 62 | |
| testis | 6 / 330442 | 18 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 8 / 232878 | 34 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 218341_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 57.75 | |
| Adipocyte | 18.1 | |
| AdrenalCortex | 16.35 | |
| Adrenalgland | 14.15 | |
| Amygdala | 14.55 | |
| Appendix | 10.9 | |
| AtrioventricularNode | 8.05 | |
| BDCA4+_DentriticCells | 45.15 | |
| Bonemarrow | 10.15 | |
| BronchialEpithelialCells | 42.1 | |
| CD105+_Endothelial | 21.5 | |
| CD14+_Monocytes | 120.15 | |
| CD19+_BCells(neg._sel.) | 126.6 | |
| CD33+_Myeloid | 57.2 | |
| CD34+ | 69.15 | |
| CD4+_Tcells | 63.5 | |
| CD56+_NKCells | 97.2 | |
| CD71+_EarlyErythroid | 13.55 | |
| CD8+_Tcells | 52.6 | |
| CardiacMyocytes | 19.9 | |
| Caudatenucleus | 9.2 | |
| Cerebellum | 6.8 | |
| CerebellumPeduncles | 10.4 | |
| CiliaryGanglion | 8.75 | |
| CingulateCortex | 11.15 | |
| Colorectaladenocarcinoma | 30.05 | |
| DorsalRootGanglion | 8.05 | |
| FetalThyroid | 15.05 | |
| Fetalbrain | 9.2 | |
| Fetalliver | 12 | |
| Fetallung | 10.15 | |
| GlobusPallidus | 10.65 | |
| Heart | 11.7 | |
| Hypothalamus | 15.2 | |
| Kidney | 15.9 | |
| Leukemia_chronicMyelogenousK-562 | 8.9 | |
| Leukemia_promyelocytic-HL-60 | 12.4 | |
| Leukemialymphoblastic(MOLT-4) | 9.05 | |
| Liver | 19.7 | |
| Lung | 22.15 | |
| Lymphnode | 18.7 | |
| Lymphoma_burkitts(Daudi) | 18.75 | |
| Lymphoma_burkitts(Raji) | 24.3 | |
| MedullaOblongata | 8.75 | |
| OccipitalLobe | 11.8 | |
| OlfactoryBulb | 10.4 | |
| Ovary | 11 | |
| Pancreas | 23.85 | |
| PancreaticIslet | 26.7 | |
| ParietalLobe | 9 | |
| Pituitary | 16.4 | |
| Placenta | 18.8 | |
| Pons | 9.05 | |
| PrefrontalCortex | 13.6 | |
| Prostate | 63.75 | |
| Salivarygland | 12.1 | |
| SkeletalMuscle | 10 | |
| Skin | 9.05 | |
| SmoothMuscle | 21.8 | |
| Spinalcord | 16.5 | |
| SubthalamicNucleus | 11 | |
| SuperiorCervicalGanglion | 11.45 | |
| TemporalLobe | 9.4 | |
| Testis | 7.65 | |
| TestisGermCell | 10.35 | |
| TestisIntersitial | 7.8 | |
| TestisLeydigCell | 8.9 | |
| TestisSeminiferousTubule | 9.1 | |
| Thalamus | 14.6 | |
| Thymus | 10.9 | |
| Thyroid | 107.6 | |
| Tongue | 11.5 | |
| Tonsil | 14.05 | |
| Trachea | 12.35 | |
| TrigeminalGanglion | 8.8 | |
| Uterus | 11.3 | |
| UterusCorpus | 7.45 | |
| WholeBlood | 44.4 | |
| Wholebrain | 13.7 | |
| colon | 57.95 | |
| pineal_day | 33.4 | |
| pineal_night | 32.7 | |
| retina | 25.95 | |
| small_intestine | 48.45 | |
- Probe name: A_23_P51627
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 8.69 ± 0.35 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 8.82 ± 0.12 | |
| Basal Part of Pons | 8.91 ± 0.33 | |
| Cerebellar Cortex | 8.58 ± 0.25 | |
| Cerebellar Nuclei | 9.07 ± 0.16 | |
| Claustrum | 8.49 ± 0.52 | |
| Epithalamus | 9.1 ± 0.26 | |
| Frontal Lobe | 8.96 ± 0.31 | |
| Globus Pallidus | 9.29 ± 0.33 | |
| Hypothalamus | 9.09 ± 0.2 | |
| Insula | 9.08 ± 0.27 | |
| Limbic Lobe | 8.68 ± 0.54 | |
| Mesencephalon | 8.79 ± 0.37 | |
| Myelencephalon | 8.81 ± 0.4 | |
| Occipital Lobe | 8.32 ± 0.4 | |
| Parietal Lobe | 8.8 ± 0.36 | |
| Pontine Tegmentum | 8.85 ± 0.37 | |
| Striatum | 8.78 ± 0.34 | |
| Subthalamus | 9 ± 0.2 | |
| Temporal Lobe | 8.97 ± 0.33 | |
| Thalamus | 8.72 ± 0.31 | |
| White Matter | 8.46 ± 0.24 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ppcs | CB | Cerebellum | 10.54 | |
| 10.99 | | |||
| Ppcs | CTX | Cerebral cortex | 12.15 | |
| 8.27 | | |||
| Ppcs | HIP | Hippocampal region | 8.21 | |
| 7.43 | | |||
| Ppcs | HPF | Hippocampal formation | 13.41 | |
| 10.68 | | |||
| Ppcs | HY | Hypothalamus | 9.88 | |
| 7.44 | | |||
| Ppcs | LSX | Lateral septal complex | 1.79 | |
| 1.43 | | |||
| Ppcs | MB | Midbrain | 9.99 | |
| 9.56 | | |||
| Ppcs | MY | Medulla | 27.77 | |
| 31.61 | | |||
| Ppcs | OLF | Olfactory bulb | 23.87 | |
| 17.26 | | |||
| Ppcs | P | Pons | 27.21 | |
| 29.55 | | |||
| Ppcs | PAL | Pallidum | 11.25 | |
| 9.59 | | |||
| Ppcs | RHP | Retrohippocampal region | 26.7 | |
| 18.24 | | |||
| Ppcs | sAMY | Striatum-like amygdalar nuclei | 15.43 | |
| 9.86 | | |||
| Ppcs | STR | Striatum | 8.82 | |
| 6.06 | | |||
| Ppcs | STRd | Striatum dorsal region | 6.39 | |
| 4.56 | | |||
| Ppcs | STRv | Striatum ventral region | 14.88 | |
| 9.41 | | |||
| Ppcs | TH | Thalamus | 5.64 | |
| 4.17 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00163726 | 10 | 37 | 46 | VVLVTSGGTK | Peptide Atlas |
| PPCS_HUMAN_2 | 17 | 2 | 18 | AEMDPVAEFPQPPGAAR | PRIDE |
| PPCS_HUMAN_263 | 24 | 263 | 286 | QSFVFIVTKDSETKLLLSEEEIEK | PRIDE |