AutismKB 2.0

Annotation Detail for TBL1XR1


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Basic Information Top
Gene Symbol:TBL1XR1 ( C21,DC42,FLJ12894,IRA1,TBLR1 )
Gene Full Name: transducin (beta)-like 1 X-linked receptor 1
Band: 3q26.32
Quick LinksEntrez ID:79718; OMIM: 608628; Uniprot ID:TBL1R_HUMAN; ENSEMBL ID: ENSG00000177565; HGNC ID: 29529
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst5 / 6231980
fetus73 / 564012129
neonate1 / 3109732
infant2 / 2362084
juvenile3 / 5555653
adult216 / 1939121111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma5 / 17475286
breast (mammary gland) tumor12 / 94178127
cervical tumor3 / 3436687
chondrosarcoma9 / 82823108
colorectal tumor10 / 11424687
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor23 / 26384587
glioma6 / 10688356
head and neck tumor21 / 136302154
kidney tumor9 / 68959130
leukemia12 / 95842125
liver tumor17 / 96359176
lung tumor4 / 10312738
lymphoma5 / 7175569
non-neoplasia11 / 97250113
normal317 / 336030794
ovarian tumor9 / 76682117
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer17 / 102680165
retinoblastoma0 / 463560 
skin tumor23 / 124949184
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor25 / 90257276
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland6 / 33197180
ascites0 / 400150 
bladder8 / 29757268
blood4 / 12347832
bone2 / 7165527
bone marrow9 / 48801184
brain93 / 110098984
cervix3 / 4817162
connective tissue12 / 14925580
ear11 / 16212678
embryonic tissue23 / 215722106
esophagus0 / 202090 
eye13 / 21105461
heart14 / 89626156
intestine21 / 23447289
kidney17 / 21177780
larynx4 / 24145165
liver24 / 207743115
lung38 / 336974112
lymph2 / 4427045
lymph node25 / 91610272
mammary gland19 / 153271123
mouth11 / 67052164
muscle13 / 107715120
nerve3 / 15768190
ovary11 / 102051107
pancreas24 / 214812111
parathyroid3 / 20539146
pharynx6 / 41328145
pituitary gland0 / 165850 
placenta13 / 28082546
prostate26 / 189345137
salivary gland7 / 20155347
skin28 / 210574132
spleen2 / 5395237
stomach5 / 9661951
testis22 / 33044266
thymus15 / 81131184
thyroid2 / 4747342
tonsil0 / 169990 
trachea17 / 52413324
umbilical cord0 / 136800 
uterus37 / 232878158
vascular10 / 51780193
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221428_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts237.15
Adipocyte135.35
AdrenalCortex73.65
Adrenalgland50.25
Amygdala138.15
Appendix71.6
AtrioventricularNode56.7
BDCA4+_DentriticCells133.45
Bonemarrow62.75
BronchialEpithelialCells95.35
CD105+_Endothelial54.4
CD14+_Monocytes59
CD19+_BCells(neg._sel.)65.65
CD33+_Myeloid83.5
CD34+157.25
CD4+_Tcells160.7
CD56+_NKCells67.75
CD71+_EarlyErythroid54.15
CD8+_Tcells132.15
CardiacMyocytes74.7
Caudatenucleus59.15
Cerebellum48.15
CerebellumPeduncles73.25
CiliaryGanglion48.25
CingulateCortex75.05
Colorectaladenocarcinoma102.7
DorsalRootGanglion56.25
FetalThyroid63.25
Fetalbrain113.95
Fetalliver58.6
Fetallung92.8
GlobusPallidus48.45
Heart83.45
Hypothalamus74.9
Kidney52.8
Leukemia_chronicMyelogenousK-56254.8
Leukemia_promyelocytic-HL-60112.3
Leukemialymphoblastic(MOLT-4)183.95
Liver88.25
Lung57.75
Lymphnode70
Lymphoma_burkitts(Daudi)204.5
Lymphoma_burkitts(Raji)99.35
MedullaOblongata53.1
OccipitalLobe110.75
OlfactoryBulb46.55
Ovary46.4
Pancreas75.65
PancreaticIslet64
ParietalLobe70.55
Pituitary58.45
Placenta73.4
Pons58.7
PrefrontalCortex124.2
Prostate62.8
Salivarygland98.3
SkeletalMuscle70.95
Skin48.75
SmoothMuscle91.75
Spinalcord64.95
SubthalamicNucleus54.05
SuperiorCervicalGanglion86.65
TemporalLobe58.15
Testis41.3
TestisGermCell46.9
TestisIntersitial50.95
TestisLeydigCell59.8
TestisSeminiferousTubule51.9
Thalamus62.95
Thymus45.25
Thyroid239.7
Tongue60.8
Tonsil67.55
Trachea76.8
TrigeminalGanglion57.85
Uterus104.8
UterusCorpus61.05
WholeBlood148.55
Wholebrain55.3
colon218.7
pineal_day277.58
pineal_night257.96
retina101.575
small_intestine142.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P57989
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.96 ± 0.31
Basal Forebrain7.74 ± 0.17
Basal Part of Pons7.58 ± 0.28
Cerebellar Cortex7.6 ± 0.24
Cerebellar Nuclei7.28 ± 0.24
Claustrum8.19 ± 0.32
Epithalamus7.64 ± 0.17
Frontal Lobe7.7 ± 0.32
Globus Pallidus7.59 ± 0.26
Hypothalamus7.32 ± 0.16
Insula7.68 ± 0.35
Limbic Lobe8.02 ± 0.29
Mesencephalon7.74 ± 0.36
Myelencephalon7.79 ± 0.32
Occipital Lobe8.14 ± 0.34
Parietal Lobe7.8 ± 0.29
Pontine Tegmentum7.73 ± 0.27
Striatum8.02 ± 0.23
Subthalamus7.37 ± 0.22
Temporal Lobe7.71 ± 0.3
Thalamus7.82 ± 0.35
White Matter7.38 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tbl1xr1CBCerebellum8.82
9.6
Tbl1xr1CTXCerebral cortex30.81
21.76
Tbl1xr1HIPHippocampal region31.68
36.08
Tbl1xr1HPFHippocampal formation33.9
32.88
Tbl1xr1HYHypothalamus2.04
1.71
Tbl1xr1LSXLateral septal complex6.44
5.04
Tbl1xr1MBMidbrain7.99
7.84
Tbl1xr1MYMedulla6.13
5.94
Tbl1xr1OLFOlfactory bulb27.11
22.02
Tbl1xr1PPons7.99
7.87
Tbl1xr1PALPallidum1.54
1.16
Tbl1xr1RHPRetrohippocampal region37.45
29.24
Tbl1xr1sAMYStriatum-like amygdalar nuclei1.96
1.7
Tbl1xr1STRStriatum6.76
4.8
Tbl1xr1STRdStriatum dorsal region8.03
5.74
Tbl1xr1STRvStriatum ventral region4.98
3.28
Tbl1xr1THThalamus8.41
6.72
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001449 17 465 481 CVHIWNTQTGALVHSYR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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