AutismKB 2.0

Annotation Detail for ZNF668


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Basic Information Top
Gene Symbol:ZNF668 ( FLJ13479,FLJ14492 )
Gene Full Name: zinc finger protein 668
Band: 16p11.2
Quick LinksEntrez ID:79759; OMIM: NA; Uniprot ID:ZN668_HUMAN; ENSEMBL ID: ENSG00000167394; HGNC ID: 25821
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst3 / 6231948
fetus52 / 56401292
neonate2 / 3109764
infant3 / 23620127
juvenile5 / 5555689
adult52 / 193912126
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult1 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor2 / 17290115
gastrointestinal tumor2 / 11936916
germ cell tumor18 / 26384568
glioma2 / 10688318
head and neck tumor17 / 136302124
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal170 / 336030750
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal0 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder1 / 2975733
blood1 / 1234788
bone4 / 7165555
bone marrow5 / 48801102
brain90 / 110098981
cervix1 / 4817120
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus2 / 2020998
eye2 / 2110549
heart2 / 8962622
intestine19 / 23447281
kidney8 / 21177737
larynx0 / 241450 
liver6 / 20774328
lung10 / 33697429
lymph0 / 442700 
lymph node6 / 9161065
mammary gland3 / 15327119
mouth14 / 67052208
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas4 / 21481218
parathyroid5 / 20539243
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta8 / 28082528
prostate11 / 18934558
salivary gland1 / 2015549
skin21 / 21057499
spleen4 / 5395274
stomach1 / 9661910
testis14 / 33044242
thymus7 / 8113186
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord1 / 1368073
uterus14 / 23287860
vascular3 / 5178057
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain4 / 11009893
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219047_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.8
Adipocyte9.25
AdrenalCortex10.6
Adrenalgland8.05
Amygdala9.9
Appendix10.4
AtrioventricularNode8
BDCA4+_DentriticCells10.4
Bonemarrow9.8
BronchialEpithelialCells9
CD105+_Endothelial9.4
CD14+_Monocytes10.05
CD19+_BCells(neg._sel.)9.45
CD33+_Myeloid11.7
CD34+11.8
CD4+_Tcells10.1
CD56+_NKCells10.65
CD71+_EarlyErythroid8.8
CD8+_Tcells7.85
CardiacMyocytes12.3
Caudatenucleus8.45
Cerebellum7.6
CerebellumPeduncles12.55
CiliaryGanglion7.75
CingulateCortex9.65
Colorectaladenocarcinoma9.25
DorsalRootGanglion7.6
FetalThyroid9
Fetalbrain9.2
Fetalliver8.25
Fetallung7.75
GlobusPallidus7.05
Heart12
Hypothalamus9.9
Kidney8
Leukemia_chronicMyelogenousK-5628.45
Leukemia_promyelocytic-HL-608.3
Leukemialymphoblastic(MOLT-4)7.6
Liver13.55
Lung10.4
Lymphnode8.05
Lymphoma_burkitts(Daudi)12
Lymphoma_burkitts(Raji)13.3
MedullaOblongata8.55
OccipitalLobe8.45
OlfactoryBulb7.4
Ovary6.25
Pancreas7.35
PancreaticIslet9.95
ParietalLobe10
Pituitary11
Placenta9.5
Pons9.1
PrefrontalCortex11.55
Prostate10.45
Salivarygland7.9
SkeletalMuscle14.35
Skin7.65
SmoothMuscle10.35
Spinalcord10.1
SubthalamicNucleus8.6
SuperiorCervicalGanglion12.7
TemporalLobe8.6
Testis7.95
TestisGermCell7.6
TestisIntersitial7.55
TestisLeydigCell9.95
TestisSeminiferousTubule7.95
Thalamus9.6
Thymus7.3
Thyroid9.9
Tongue9.35
Tonsil9.15
Trachea7.85
TrigeminalGanglion10
Uterus7.75
UterusCorpus10.65
WholeBlood9.3
Wholebrain8.95
colon8.85
pineal_day13.78
pineal_night12.1
retina11.075
small_intestine8.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1582_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.9 ± 0.95
Basal Forebrain2.28 ± 0.3
Basal Part of Pons1.99 ± 0.69
Cerebellar Cortex2.42 ± 0.77
Cerebellar Nuclei2.66 ± 0.64
Claustrum3.03 ± 0.96
Epithalamus1.96 ± 0.76
Frontal Lobe2.38 ± 0.76
Globus Pallidus2.31 ± 0.67
Hypothalamus2.14 ± 0.7
Insula2.23 ± 0.72
Limbic Lobe2.57 ± 0.77
Mesencephalon2.68 ± 0.73
Myelencephalon2.51 ± 0.71
Occipital Lobe2.68 ± 0.76
Parietal Lobe2.43 ± 0.68
Pontine Tegmentum2.37 ± 0.68
Striatum2.41 ± 0.68
Subthalamus2.64 ± 0.86
Temporal Lobe2.32 ± 0.7
Thalamus2.38 ± 0.74
White Matter2.12 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp668CBCerebellum14.22
15.53
Zfp668CTXCerebral cortex20.3
14.79
Zfp668HIPHippocampal region22.04
24.16
Zfp668HPFHippocampal formation18.62
18.18
Zfp668HYHypothalamus2.59
1.99
Zfp668LSXLateral septal complex3.65
2.59
Zfp668MBMidbrain3.64
3.36
Zfp668MYMedulla7.47
8
Zfp668OLFOlfactory bulb21.26
17.05
Zfp668PPons3.6
3.84
Zfp668PALPallidum3.53
3.26
Zfp668RHPRetrohippocampal region13.29
10.54
Zfp668sAMYStriatum-like amygdalar nuclei4.85
3.5
Zfp668STRStriatum8.42
6.19
Zfp668STRdStriatum dorsal region8.6
6.51
Zfp668STRvStriatum ventral region11.53
7.79
Zfp668THThalamus7.77
6.45
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010335 26 40 65 HAATHGPADCSEEVAEVKPKPETEAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018