AutismKB 2.0

Annotation Detail for FZD3


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Basic Information Top
Gene Symbol:FZD3 ( Fz-3,hFz3 )
Gene Full Name: frizzled homolog 3 (Drosophila)
Band: 8p21.1
Quick LinksEntrez ID:7976; OMIM: 606143; Uniprot ID:FZD3_HUMAN; ENSEMBL ID: ENSG00000104290; HGNC ID: 4041
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult17 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor5 / 26384518
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal41 / 336030712
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain17 / 110098915
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus1 / 2020949
eye2 / 2110549
heart2 / 8962622
intestine3 / 23447212
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node5 / 9161054
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach1 / 9661910
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219683_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.85
Adipocyte10.75
AdrenalCortex16.75
Adrenalgland10.05
Amygdala18.25
Appendix21.8
AtrioventricularNode15.3
BDCA4+_DentriticCells11.55
Bonemarrow13.2
BronchialEpithelialCells10.45
CD105+_Endothelial11.2
CD14+_Monocytes11.9
CD19+_BCells(neg._sel.)11.4
CD33+_Myeloid13.6
CD34+13.05
CD4+_Tcells10.6
CD56+_NKCells11.1
CD71+_EarlyErythroid10.75
CD8+_Tcells9.95
CardiacMyocytes17.95
Caudatenucleus10.15
Cerebellum9.35
CerebellumPeduncles13.95
CiliaryGanglion13.45
CingulateCortex23.5
Colorectaladenocarcinoma11.25
DorsalRootGanglion10.6
FetalThyroid11.2
Fetalbrain10.85
Fetalliver10.55
Fetallung7.35
GlobusPallidus11.2
Heart16.75
Hypothalamus11.6
Kidney11.8
Leukemia_chronicMyelogenousK-5629.75
Leukemia_promyelocytic-HL-609.65
Leukemialymphoblastic(MOLT-4)7.75
Liver18.35
Lung11.95
Lymphnode8.4
Lymphoma_burkitts(Daudi)14.95
Lymphoma_burkitts(Raji)17.1
MedullaOblongata10.3
OccipitalLobe17.8
OlfactoryBulb8.7
Ovary10.6
Pancreas10.7
PancreaticIslet12.2
ParietalLobe14.2
Pituitary13.35
Placenta9.95
Pons12.8
PrefrontalCortex38.35
Prostate12.9
Salivarygland9.7
SkeletalMuscle25.7
Skin15.5
SmoothMuscle12.65
Spinalcord11.85
SubthalamicNucleus13.25
SuperiorCervicalGanglion26.9
TemporalLobe11.3
Testis9.45
TestisGermCell15.4
TestisIntersitial10.25
TestisLeydigCell12.25
TestisSeminiferousTubule9.85
Thalamus12.05
Thymus7.6
Thyroid12.4
Tongue14.5
Tonsil11.2
Trachea9.3
TrigeminalGanglion20.6
Uterus8.95
UterusCorpus13.65
WholeBlood11.4
Wholebrain8.95
colon10.5
pineal_day53.62
pineal_night64.1
retina19
small_intestine9.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9827_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.07 ± 0.51
Basal Forebrain5.9 ± 0.66
Basal Part of Pons6.32 ± 0.37
Cerebellar Cortex5.72 ± 0.29
Cerebellar Nuclei5.11 ± 0.36
Claustrum6.33 ± 0.2
Epithalamus7.15 ± 0.64
Frontal Lobe5.9 ± 0.48
Globus Pallidus4.37 ± 0.61
Hypothalamus6.23 ± 0.42
Insula5.82 ± 0.54
Limbic Lobe5.85 ± 0.51
Mesencephalon5.8 ± 0.49
Myelencephalon5.82 ± 0.62
Occipital Lobe6 ± 0.48
Parietal Lobe5.86 ± 0.47
Pontine Tegmentum5.74 ± 0.64
Striatum6.11 ± 0.52
Subthalamus5.46 ± 0.47
Temporal Lobe5.94 ± 0.48
Thalamus5.57 ± 0.4
White Matter3.72 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fzd3CBCerebellum1.36
1.51
Fzd3CTXCerebral cortex29.82
21.84
Fzd3HIPHippocampal region34.58
18.91
Fzd3HPFHippocampal formation31.79
19.84
Fzd3HYHypothalamus3.22
2.17
Fzd3LSXLateral septal complex12.65
7.74
Fzd3MBMidbrain1.01
0.72
Fzd3MYMedulla1.23
0.92
Fzd3OLFOlfactory bulb51.7
36.18
Fzd3PPons0.62
0.52
Fzd3PALPallidum2.77
1.85
Fzd3RHPRetrohippocampal region26.71
19.9
Fzd3sAMYStriatum-like amygdalar nuclei16.01
9.89
Fzd3STRStriatum13.98
8.54
Fzd3STRdStriatum dorsal region10.71
6.73
Fzd3STRvStriatum ventral region22.74
12.34
Fzd3THThalamus3.91
2.21
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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