AutismKB 2.0

Annotation Detail for ELMO3


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Basic Information Top
Gene Symbol:ELMO3 ( CED-12,CED12,ELMO-3,FLJ13824 )
Gene Full Name: engulfment and cell motility 3
Band: 16q22.1
Quick LinksEntrez ID:79767; OMIM: 606422; Uniprot ID:ELMO3_HUMAN; ENSEMBL ID: ENSG00000102890; HGNC ID: 17289
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor7 / 11424661
esophageal tumor3 / 17290173
gastrointestinal tumor6 / 11936950
germ cell tumor5 / 26384518
glioma3 / 10688328
head and neck tumor6 / 13630244
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal55 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites6 / 40015149
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain6 / 11009895
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus3 / 20209148
eye2 / 2110549
heart0 / 896260 
intestine15 / 23447263
kidney7 / 21177733
larynx2 / 2414582
liver3 / 20774314
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth3 / 6705244
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta9 / 28082532
prostate14 / 18934573
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach0 / 966190 
testis5 / 33044215
thymus1 / 8113112
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219411_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.45
Adipocyte3.4
AdrenalCortex3.55
Adrenalgland2.85
Amygdala3.6
Appendix3.4
AtrioventricularNode2.6
BDCA4+_DentriticCells3.8
Bonemarrow3.3
BronchialEpithelialCells11.2
CD105+_Endothelial6.6
CD14+_Monocytes3.65
CD19+_BCells(neg._sel.)3.7
CD33+_Myeloid4.4
CD34+4.35
CD4+_Tcells3.95
CD56+_NKCells4.15
CD71+_EarlyErythroid128.55
CD8+_Tcells3.45
CardiacMyocytes4.35
Caudatenucleus3.05
Cerebellum2.7
CerebellumPeduncles3.85
CiliaryGanglion2.35
CingulateCortex3.5
Colorectaladenocarcinoma12.5
DorsalRootGanglion2.6
FetalThyroid3.9
Fetalbrain3.35
Fetalliver2.95
Fetallung2.85
GlobusPallidus2.5
Heart4.35
Hypothalamus3.75
Kidney2.9
Leukemia_chronicMyelogenousK-5623.1
Leukemia_promyelocytic-HL-603
Leukemialymphoblastic(MOLT-4)2.75
Liver5.95
Lung4.25
Lymphnode2.95
Lymphoma_burkitts(Daudi)4.3
Lymphoma_burkitts(Raji)4.75
MedullaOblongata3.1
OccipitalLobe3.1
OlfactoryBulb2.7
Ovary2.25
Pancreas3.4
PancreaticIslet5.8
ParietalLobe3.55
Pituitary11.35
Placenta9.2
Pons3.25
PrefrontalCortex4.25
Prostate7.25
Salivarygland2.7
SkeletalMuscle3.95
Skin2.85
SmoothMuscle3.85
Spinalcord3.65
SubthalamicNucleus3.1
SuperiorCervicalGanglion3.8
TemporalLobe3.1
Testis6.55
TestisGermCell3
TestisIntersitial3.25
TestisLeydigCell3.6
TestisSeminiferousTubule2.9
Thalamus3.45
Thymus2.7
Thyroid11.7
Tongue3.35
Tonsil3.35
Trachea2.85
TrigeminalGanglion3.35
Uterus2.8
UterusCorpus3.05
WholeBlood3.75
Wholebrain2.9
colon14.95
pineal_day4.28
pineal_night4.18
retina4.15
small_intestine3.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8343_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.5 ± 0.92
Basal Forebrain1.94 ± 0.22
Basal Part of Pons1.76 ± 0.38
Cerebellar Cortex2.09 ± 0.8
Cerebellar Nuclei2.32 ± 0.73
Claustrum2.95 ± 0.81
Epithalamus1.74 ± 0.82
Frontal Lobe1.95 ± 0.72
Globus Pallidus2.57 ± 0.32
Hypothalamus2.08 ± 0.69
Insula1.86 ± 0.45
Limbic Lobe2.1 ± 0.63
Mesencephalon2.25 ± 0.7
Myelencephalon2.1 ± 0.69
Occipital Lobe2.16 ± 0.83
Parietal Lobe2.02 ± 0.56
Pontine Tegmentum2.1 ± 0.69
Striatum2.09 ± 0.5
Subthalamus2.2 ± 0.66
Temporal Lobe2.03 ± 0.78
Thalamus2.04 ± 0.59
White Matter2.48 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Elmo3CBCerebellum2.58
3.33
Elmo3CTXCerebral cortex1.87
1.9
Elmo3HIPHippocampal region0.96
1.24
Elmo3HPFHippocampal formation0.67
0.87
Elmo3HYHypothalamus1.62
1.4
Elmo3LSXLateral septal complex1.07
1.39
Elmo3MBMidbrain0.98
1.43
Elmo3MYMedulla1.81
2.51
Elmo3OLFOlfactory bulb2.42
2.13
Elmo3PPons1.05
1.41
Elmo3PALPallidum1.19
0.98
Elmo3RHPRetrohippocampal region0.32
0.54
Elmo3sAMYStriatum-like amygdalar nuclei1.37
1.2
Elmo3STRStriatum1.44
1.38
Elmo3STRdStriatum dorsal region1.54
1.6
Elmo3STRvStriatum ventral region1.31
0.87
Elmo3THThalamus1.29
1.23
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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