AutismKB 2.0

Annotation Detail for MYH14


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Basic Information Top
Gene Symbol:MYH14 ( DFNA4,DKFZp667A1311,FLJ13881,FLJ43092,KIAA2034,MHC16,MYH17,NMHC-II-C,myosin )
Gene Full Name: myosin, heavy chain 14, non-muscle
Band: 19q13.33
Quick LinksEntrez ID:79784; OMIM: 608568; Uniprot ID:MYH14_HUMAN; ENSEMBL ID: ENSG00000105357; HGNC ID: 23212
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult93 / 193912147
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor27 / 114246236
esophageal tumor2 / 17290115
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma6 / 10688356
head and neck tumor9 / 13630266
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal73 / 336030721
ovarian tumor3 / 7668239
pancreatic tumor15 / 104616143
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer11 / 102680107
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain18 / 110098916
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus2 / 2020998
eye13 / 21105461
heart0 / 896260 
intestine47 / 234472200
kidney11 / 21177751
larynx4 / 24145165
liver3 / 20774314
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland9 / 15327158
mouth2 / 6705229
muscle4 / 10771537
nerve0 / 157680 
ovary3 / 10205129
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta3 / 28082510
prostate13 / 18934568
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach2 / 9661920
testis2 / 3304426
thymus1 / 8113112
thyroid7 / 47473147
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217660_at
Cell line Expression level Expression bar
721_B_lymphoblasts7
Adipocyte6.1
AdrenalCortex7.1
Adrenalgland5.35
Amygdala6.25
Appendix6.7
AtrioventricularNode5.25
BDCA4+_DentriticCells6.3
Bonemarrow6.55
BronchialEpithelialCells6.1
CD105+_Endothelial6.25
CD14+_Monocytes6.6
CD19+_BCells(neg._sel.)6.4
CD33+_Myeloid7.65
CD34+7.4
CD4+_Tcells6.75
CD56+_NKCells7.15
CD71+_EarlyErythroid6
CD8+_Tcells6
CardiacMyocytes8.9
Caudatenucleus5.65
Cerebellum5.15
CerebellumPeduncles7.6
CiliaryGanglion4.55
CingulateCortex6.6
Colorectaladenocarcinoma6.35
DorsalRootGanglion6.9
FetalThyroid5.85
Fetalbrain6.05
Fetalliver5.5
Fetallung4.8
GlobusPallidus4.8
Heart8.75
Hypothalamus6.5
Kidney5.35
Leukemia_chronicMyelogenousK-5625.6
Leukemia_promyelocytic-HL-605.55
Leukemialymphoblastic(MOLT-4)4.9
Liver9
Lung6.75
Lymphnode5.05
Lymphoma_burkitts(Daudi)8.75
Lymphoma_burkitts(Raji)9.5
MedullaOblongata9.85
OccipitalLobe5.65
OlfactoryBulb4.9
Ovary4.25
Pancreas5.1
PancreaticIslet6.65
ParietalLobe6.85
Pituitary7.35
Placenta5.95
Pons6.2
PrefrontalCortex7.55
Prostate7.15
Salivarygland5.1
SkeletalMuscle8.7
Skin5.3
SmoothMuscle7.05
Spinalcord6.65
SubthalamicNucleus5.8
SuperiorCervicalGanglion7.35
TemporalLobe5.75
Testis5.35
TestisGermCell5
TestisIntersitial5.2
TestisLeydigCell6.35
TestisSeminiferousTubule5.4
Thalamus9.75
Thymus4.7
Thyroid7.55
Tongue6.7
Tonsil6.1
Trachea5.25
TrigeminalGanglion7.05
Uterus4.95
UterusCorpus5.9
WholeBlood6.5
Wholebrain5
colon6.35
pineal_day7.74
pineal_night11.3
retina7.55
small_intestine6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P78734
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.48 ± 0.61
Basal Forebrain8.34 ± 0.25
Basal Part of Pons8.44 ± 0.4
Cerebellar Cortex8.04 ± 0.27
Cerebellar Nuclei8.66 ± 0.32
Claustrum8.62 ± 0.48
Epithalamus7.75 ± 0.29
Frontal Lobe8.36 ± 0.51
Globus Pallidus8.77 ± 0.31
Hypothalamus8.13 ± 0.63
Insula8.15 ± 0.44
Limbic Lobe8.37 ± 0.48
Mesencephalon8.36 ± 0.47
Myelencephalon8.37 ± 0.48
Occipital Lobe8.38 ± 0.45
Parietal Lobe8.29 ± 0.44
Pontine Tegmentum8.23 ± 0.36
Striatum8.69 ± 0.44
Subthalamus8.26 ± 0.22
Temporal Lobe8.23 ± 0.49
Thalamus8.45 ± 0.36
White Matter8.48 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Myh14CBCerebellum100
100
Myh14CTXCerebral cortex73.73
68.22
Myh14HIPHippocampal region39.34
51
Myh14HPFHippocampal formation38.97
44.37
Myh14HYHypothalamus47.51
52.68
Myh14LSXLateral septal complex11.63
9.96
Myh14MBMidbrain39.2
40.58
Myh14MYMedulla72.18
94.62
Myh14OLFOlfactory bulb64.53
66.69
Myh14PPons50.73
63.75
Myh14PALPallidum56.65
61.85
Myh14RHPRetrohippocampal region38.12
34.8
Myh14sAMYStriatum-like amygdalar nuclei65.01
57.36
Myh14STRStriatum61.35
51.01
Myh14STRdStriatum dorsal region64.75
52.44
Myh14STRvStriatum ventral region64.85
56.01
Myh14THThalamus67.59
68.96
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MYH14_HUMAN_0 0 0 0 EQADFALEALAK PRIDE
MYH14_HUMAN_0 0 0 0 FDQLLAEEK PRIDE
MYH14_HUMAN_0 0 0 0 KFDQLLAEEK PRIDE
MYH14_HUMAN_0 0 0 0 QLLQANPILEAFGNAK PRIDE
MYH14_HUMAN_1104 11 1104 1114 KEEELQAALAR PRIDE
MYH14_HUMAN_1468 10 1468 1477 KFDQLLAEEK PRIDE
MYH14_HUMAN_1469 9 1469 1477 FDQLLAEEK PRIDE
MYH14_HUMAN_1839 13 1839 1851 LAQAEEQLEQETR PRIDE
MYH14_HUMAN_189 15 189 203 EDQSILCTGESGAGK PRIDE
MYH14_HUMAN_189 20 189 208 EDQSILCTGESGAGKTENTK PRIDE
MYH14_HUMAN_189 21 189 209 EDQSILCTGESGAGKTENTKK PRIDE
MYH14_HUMAN_236 16 236 251 QLLQANPILEAFGNAK PRIDE
MYH14_HUMAN_433 12 433 444 EQADFALEALAK PRIDE
MYH14_HUMAN_717 9 717 725 CNGVLEGIR PRIDE
MYH14_HUMAN_766 13 766 778 MIQALELDPNLYR PRIDE
MYH14_HUMAN_985 11 985 995 LQLEKVTTEAK PRIDE
PAp00001228 9 759 767 CNGVLEGIR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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