AutismKB 2.0

Annotation Detail for KLHL36


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Basic Information Top
Gene Symbol:KLHL36 ( C16orf44,FLJ12543 )
Gene Full Name: kelch-like 36 (Drosophila)
Band: 16q24.1
Quick LinksEntrez ID:79786; OMIM: NA; Uniprot ID:KLH36_HUMAN; ENSEMBL ID: ENSG00000135686; HGNC ID: 17844
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor13 / 26384549
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma3 / 7175541
non-neoplasia1 / 9725010
normal44 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone0 / 716550 
bone marrow1 / 4880120
brain17 / 110098915
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus2 / 2020998
eye2 / 2110549
heart0 / 896260 
intestine6 / 23447225
kidney6 / 21177728
larynx0 / 241450 
liver1 / 2077434
lung8 / 33697423
lymph1 / 4427022
lymph node4 / 9161043
mammary gland4 / 15327126
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate2 / 18934510
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach6 / 9661962
testis8 / 33044224
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219453_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.65
Adipocyte4.45
AdrenalCortex4.8
Adrenalgland3.8
Amygdala4.7
Appendix4.55
AtrioventricularNode3.6
BDCA4+_DentriticCells5.05
Bonemarrow4.75
BronchialEpithelialCells4.4
CD105+_Endothelial4.45
CD14+_Monocytes6.65
CD19+_BCells(neg._sel.)14.95
CD33+_Myeloid6.05
CD34+5.8
CD4+_Tcells5.1
CD56+_NKCells8.4
CD71+_EarlyErythroid4.25
CD8+_Tcells4.55
CardiacMyocytes5.95
Caudatenucleus4.05
Cerebellum3.65
CerebellumPeduncles5.15
CiliaryGanglion3.25
CingulateCortex4.65
Colorectaladenocarcinoma4.6
DorsalRootGanglion3.5
FetalThyroid4.35
Fetalbrain4.45
Fetalliver4
Fetallung3.7
GlobusPallidus3.3
Heart5.9
Hypothalamus4.85
Kidney3.7
Leukemia_chronicMyelogenousK-5624.1
Leukemia_promyelocytic-HL-604.05
Leukemialymphoblastic(MOLT-4)3.55
Liver6
Lung5.1
Lymphnode3.85
Lymphoma_burkitts(Daudi)5.85
Lymphoma_burkitts(Raji)6.4
MedullaOblongata4
OccipitalLobe4
OlfactoryBulb3.55
Ovary3.15
Pancreas3.7
PancreaticIslet4.9
ParietalLobe4.8
Pituitary5.3
Placenta4.65
Pons4.3
PrefrontalCortex5.65
Prostate5.25
Salivarygland3.65
SkeletalMuscle5.5
Skin3.5
SmoothMuscle5.1
Spinalcord4.8
SubthalamicNucleus4.1
SuperiorCervicalGanglion5.3
TemporalLobe4.15
Testis4.25
TestisGermCell3.75
TestisIntersitial3.95
TestisLeydigCell4.5
TestisSeminiferousTubule3.9
Thalamus4.65
Thymus3.4
Thyroid9.8
Tongue4.65
Tonsil4.45
Trachea3.75
TrigeminalGanglion4.85
Uterus3.65
UterusCorpus4.35
WholeBlood4.95
Wholebrain3.8
colon4.6
pineal_day5.7
pineal_night5.58
retina6.05
small_intestine4.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6041_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.99 ± 0.43
Basal Forebrain4.68 ± 0.29
Basal Part of Pons5.1 ± 0.27
Cerebellar Cortex5.09 ± 0.34
Cerebellar Nuclei4.82 ± 0.42
Claustrum4.74 ± 0.58
Epithalamus4.55 ± 0.35
Frontal Lobe5.03 ± 0.41
Globus Pallidus4.15 ± 0.67
Hypothalamus4.48 ± 0.39
Insula4.97 ± 0.34
Limbic Lobe5.1 ± 0.38
Mesencephalon4.84 ± 0.41
Myelencephalon4.99 ± 0.44
Occipital Lobe4.91 ± 0.32
Parietal Lobe4.95 ± 0.37
Pontine Tegmentum4.73 ± 0.42
Striatum4.83 ± 0.31
Subthalamus4.86 ± 0.16
Temporal Lobe5.05 ± 0.36
Thalamus4.88 ± 0.37
White Matter4.57 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
BC025816CBCerebellum5.51
4.35
BC025816CTXCerebral cortex6.09
3.56
BC025816HIPHippocampal region17.57
8.28
BC025816HPFHippocampal formation19.54
11.78
BC025816HYHypothalamus12.16
6.48
BC025816LSXLateral septal complex1.73
0.87
BC025816MBMidbrain10.62
7.17
BC025816MYMedulla7.03
5.17
BC025816OLFOlfactory bulb26.76
14.47
BC025816PPons19.46
14.12
BC025816PALPallidum5.46
3.32
BC025816RHPRetrohippocampal region21.66
15.09
BC025816sAMYStriatum-like amygdalar nuclei9.89
4.72
BC025816STRStriatum3.71
1.79
BC025816STRdStriatum dorsal region2.41
1.23
BC025816STRvStriatum ventral region6.31
2.65
BC025816THThalamus5.56
3.15
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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