AutismKB 2.0

Annotation Detail for NIPAL2


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Basic Information Top
Gene Symbol:NIPAL2 ( FLJ13955,NPAL2 )
Gene Full Name: NIPA-like domain containing 2
Band: 8q22.2
Quick LinksEntrez ID:79815; OMIM: NA; Uniprot ID:NPAL2_HUMAN; ENSEMBL ID: ENSG00000104361; HGNC ID: 25854
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult40 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia12 / 95842125
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal83 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone2 / 7165527
bone marrow3 / 4880161
brain18 / 110098916
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus1 / 2020949
eye3 / 21105414
heart8 / 8962689
intestine4 / 23447217
kidney6 / 21177728
larynx1 / 2414541
liver3 / 20774314
lung12 / 33697435
lymph0 / 442700 
lymph node3 / 9161032
mammary gland3 / 15327119
mouth5 / 6705274
muscle7 / 10771564
nerve1 / 1576863
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta1 / 2808253
prostate8 / 18934542
salivary gland1 / 2015549
skin2 / 2105749
spleen3 / 5395255
stomach5 / 9661951
testis8 / 33044224
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus13 / 23287855
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220128_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts19.85
Adipocyte17.05
AdrenalCortex17.05
Adrenalgland16.55
Amygdala12.05
Appendix20.05
AtrioventricularNode14.35
BDCA4+_DentriticCells14.65
Bonemarrow19.9
BronchialEpithelialCells12.55
CD105+_Endothelial15.05
CD14+_Monocytes11.3
CD19+_BCells(neg._sel.)13.3
CD33+_Myeloid20.9
CD34+15.95
CD4+_Tcells11.6
CD56+_NKCells13.85
CD71+_EarlyErythroid12.3
CD8+_Tcells12.7
CardiacMyocytes20.3
Caudatenucleus15
Cerebellum22.5
CerebellumPeduncles18.8
CiliaryGanglion12.6
CingulateCortex19.55
Colorectaladenocarcinoma13.15
DorsalRootGanglion14.4
FetalThyroid18.65
Fetalbrain16.85
Fetalliver17.7
Fetallung14.15
GlobusPallidus14.9
Heart21.1
Hypothalamus18.4
Kidney20.4
Leukemia_chronicMyelogenousK-56214.1
Leukemia_promyelocytic-HL-6014.75
Leukemialymphoblastic(MOLT-4)13.7
Liver19.45
Lung18.1
Lymphnode19.85
Lymphoma_burkitts(Daudi)24.45
Lymphoma_burkitts(Raji)27.95
MedullaOblongata19.25
OccipitalLobe15.05
OlfactoryBulb13.25
Ovary12.15
Pancreas14.45
PancreaticIslet16.75
ParietalLobe22.95
Pituitary27.55
Placenta15.95
Pons21.9
PrefrontalCortex19.9
Prostate18.65
Salivarygland17.3
SkeletalMuscle29.2
Skin13.25
SmoothMuscle18.9
Spinalcord17.9
SubthalamicNucleus18.75
SuperiorCervicalGanglion29.35
TemporalLobe15.25
Testis26.7
TestisGermCell14.2
TestisIntersitial14
TestisLeydigCell16.5
TestisSeminiferousTubule15.25
Thalamus16.9
Thymus13.45
Thyroid20.2
Tongue17.9
Tonsil18.4
Trachea22.35
TrigeminalGanglion22.05
Uterus11.85
UterusCorpus19.15
WholeBlood16.65
Wholebrain13.2
colon13.9
pineal_day14.72
pineal_night15.36
retina15.275
small_intestine11.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12629_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.91 ± 0.99
Basal Forebrain1.47 ± 0.21
Basal Part of Pons1.19 ± 0.41
Cerebellar Cortex1.28 ± 0.68
Cerebellar Nuclei1.79 ± 0.7
Claustrum2.23 ± 0.73
Epithalamus1.22 ± 0.69
Frontal Lobe1.3 ± 0.62
Globus Pallidus2.01 ± 0.32
Hypothalamus1.56 ± 0.69
Insula1.33 ± 0.47
Limbic Lobe1.47 ± 0.61
Mesencephalon1.62 ± 0.65
Myelencephalon1.49 ± 0.64
Occipital Lobe1.52 ± 0.59
Parietal Lobe1.56 ± 0.78
Pontine Tegmentum1.51 ± 0.65
Striatum1.73 ± 0.64
Subthalamus1.61 ± 0.59
Temporal Lobe1.36 ± 0.56
Thalamus1.46 ± 0.56
White Matter1.96 ± 0.36
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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