AutismKB 2.0

Annotation Detail for MOBKL2B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MOBKL2B ( FLJ13204,FLJ23916,MGC32960,MOB3B )
Gene Full Name: MOB1, Mps One Binder kinase activator-like 2B (yeast)
Band: 9p21.2
Quick LinksEntrez ID:79817; OMIM: NA; Uniprot ID:MOL2B_HUMAN; ENSEMBL ID: ENSG00000120162; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus13 / 56401223
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult52 / 193912126
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult2 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor10 / 26384537
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor5 / 9635951
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal76 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor4 / 9025744
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal1 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain29 / 110098926
cervix1 / 4817120
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine5 / 23447221
kidney10 / 21177747
larynx0 / 241450 
liver7 / 20774333
lung6 / 33697417
lymph0 / 442700 
lymph node2 / 9161021
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta19 / 28082567
prostate1 / 1893455
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach0 / 966190 
testis5 / 33044215
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus11 / 23287847
vascular1 / 5178019
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219265_at
Cell line Expression level Expression bar
721_B_lymphoblasts25.85
Adipocyte24.6
AdrenalCortex29.8
Adrenalgland24.1
Amygdala25.95
Appendix32.25
AtrioventricularNode18.3
BDCA4+_DentriticCells23.05
Bonemarrow37.6
BronchialEpithelialCells24.7
CD105+_Endothelial19.7
CD14+_Monocytes22
CD19+_BCells(neg._sel.)26.85
CD33+_Myeloid28.65
CD34+21.2
CD4+_Tcells27.2
CD56+_NKCells22.35
CD71+_EarlyErythroid23
CD8+_Tcells22.25
CardiacMyocytes31
Caudatenucleus23.05
Cerebellum20
CerebellumPeduncles26.85
CiliaryGanglion16.9
CingulateCortex25.2
Colorectaladenocarcinoma23.6
DorsalRootGanglion18.45
FetalThyroid27
Fetalbrain24.8
Fetalliver25.3
Fetallung21.05
GlobusPallidus18
Heart34.8
Hypothalamus28.1
Kidney19.8
Leukemia_chronicMyelogenousK-56232.15
Leukemia_promyelocytic-HL-6021.9
Leukemialymphoblastic(MOLT-4)20.15
Liver32.25
Lung32.65
Lymphnode26.25
Lymphoma_burkitts(Daudi)31.55
Lymphoma_burkitts(Raji)35.6
MedullaOblongata23.8
OccipitalLobe22.25
OlfactoryBulb19.6
Ovary20.75
Pancreas19.75
PancreaticIslet26.4
ParietalLobe28.25
Pituitary31.5
Placenta28.5
Pons31.3
PrefrontalCortex29.65
Prostate27.3
Salivarygland19.6
SkeletalMuscle27.85
Skin18.7
SmoothMuscle28.35
Spinalcord33.3
SubthalamicNucleus21.3
SuperiorCervicalGanglion29.8
TemporalLobe22.5
Testis21.55
TestisGermCell19.3
TestisIntersitial20.75
TestisLeydigCell24.4
TestisSeminiferousTubule22.95
Thalamus25.05
Thymus19.45
Thyroid31.4
Tongue23.9
Tonsil26.1
Trachea25.5
TrigeminalGanglion25.95
Uterus20.55
UterusCorpus47.75
WholeBlood27.5
Wholebrain18.6
colon31.85
pineal_day24.92
pineal_night28.62
retina31.75
small_intestine52.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P146551
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.92 ± 0.69
Basal Forebrain7.18 ± 0.4
Basal Part of Pons6.5 ± 0.51
Cerebellar Cortex5.94 ± 0.29
Cerebellar Nuclei7.55 ± 0.69
Claustrum5.72 ± 0.7
Epithalamus7.12 ± 0.3
Frontal Lobe6.59 ± 0.62
Globus Pallidus8.26 ± 0.54
Hypothalamus6.27 ± 0.7
Insula6.03 ± 0.48
Limbic Lobe6.01 ± 0.83
Mesencephalon6.87 ± 0.69
Myelencephalon6.75 ± 0.69
Occipital Lobe6.29 ± 0.73
Parietal Lobe6.45 ± 0.63
Pontine Tegmentum6.75 ± 0.6
Striatum8.23 ± 0.86
Subthalamus6.92 ± 0.53
Temporal Lobe6.22 ± 0.48
Thalamus7.26 ± 0.42
White Matter9.23 ± 0.63
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mobkl2bCBCerebellum3.97
4.34
Mobkl2bCTXCerebral cortex1.19
1.34
Mobkl2bHIPHippocampal region0.93
0.87
Mobkl2bHPFHippocampal formation1.02
1.04
Mobkl2bHYHypothalamus0.99
0.74
Mobkl2bLSXLateral septal complex0
0
Mobkl2bMBMidbrain1.53
1.52
Mobkl2bMYMedulla7.1
6.7
Mobkl2bOLFOlfactory bulb3.02
3.85
Mobkl2bPPons8.52
9.01
Mobkl2bPALPallidum1.29
1.1
Mobkl2bRHPRetrohippocampal region0.88
1.12
Mobkl2bsAMYStriatum-like amygdalar nuclei1.12
0.85
Mobkl2bSTRStriatum2.1
1.58
Mobkl2bSTRdStriatum dorsal region1.75
1.41
Mobkl2bSTRvStriatum ventral region3.96
2.53
Mobkl2bTHThalamus0.59
0.51
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved