AutismKB 2.0

Annotation Detail for ST7


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Basic Information Top
Gene Symbol:ST7 ( DKFZp762O2113,ETS7q,FAM4A,FAM4A1,HELG,RAY1,SEN4,TSG7 )
Gene Full Name: suppression of tumorigenicity 7
Band: 7q31.2
Quick LinksEntrez ID:7982; OMIM: 600833; Uniprot ID:ST7_HUMAN; ENSEMBL ID: ENSG00000004866; HGNC ID: 11351
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus39 / 56401269
neonate2 / 3109764
infant2 / 2362084
juvenile1 / 5555617
adult94 / 193912148
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor15 / 114246131
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor36 / 263845136
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor4 / 6895958
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal140 / 336030741
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer9 / 10268087
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone5 / 7165569
bone marrow0 / 488010 
brain61 / 110098955
cervix5 / 48171103
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye4 / 21105418
heart1 / 8962611
intestine18 / 23447276
kidney14 / 21177766
larynx0 / 241450 
liver4 / 20774319
lung8 / 33697423
lymph1 / 4427022
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate8 / 18934542
salivary gland0 / 201550 
skin6 / 21057428
spleen4 / 5395274
stomach0 / 966190 
testis22 / 33044266
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207524_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.7
Adipocyte4.85
AdrenalCortex5.45
Adrenalgland4.75
Amygdala5.2
Appendix8.75
AtrioventricularNode6.7
BDCA4+_DentriticCells4.55
Bonemarrow6.9
BronchialEpithelialCells4.3
CD105+_Endothelial4.2
CD14+_Monocytes4.5
CD19+_BCells(neg._sel.)4.4
CD33+_Myeloid5.4
CD34+5.4
CD4+_Tcells4
CD56+_NKCells5.05
CD71+_EarlyErythroid4.55
CD8+_Tcells4.05
CardiacMyocytes6.45
Caudatenucleus4.85
Cerebellum4.05
CerebellumPeduncles5.7
CiliaryGanglion6.4
CingulateCortex4.95
Colorectaladenocarcinoma4.85
DorsalRootGanglion8.7
FetalThyroid4.7
Fetalbrain4.8
Fetalliver4.3
Fetallung4.85
GlobusPallidus3.6
Heart6.45
Hypothalamus5.15
Kidney4.15
Leukemia_chronicMyelogenousK-5629.65
Leukemia_promyelocytic-HL-604.3
Leukemialymphoblastic(MOLT-4)3.8
Liver7.75
Lung7.95
Lymphnode4.1
Lymphoma_burkitts(Daudi)6.3
Lymphoma_burkitts(Raji)6.75
MedullaOblongata4.45
OccipitalLobe4.3
OlfactoryBulb4.3
Ovary6.75
Pancreas3.9
PancreaticIslet7.2
ParietalLobe5.15
Pituitary7.85
Placenta6.45
Pons4.7
PrefrontalCortex5.9
Prostate5.8
Salivarygland6.1
SkeletalMuscle6.4
Skin5.9
SmoothMuscle5.5
Spinalcord5.15
SubthalamicNucleus4.45
SuperiorCervicalGanglion12.55
TemporalLobe4.4
Testis5.05
TestisGermCell4
TestisIntersitial4.1
TestisLeydigCell6.05
TestisSeminiferousTubule4.45
Thalamus4.95
Thymus3.65
Thyroid6
Tongue6.65
Tonsil4.75
Trachea5.6
TrigeminalGanglion8.55
Uterus4.45
UterusCorpus5.8
WholeBlood5.2
Wholebrain4
colon4.85
pineal_day5.14
pineal_night5.1
retina5.775
small_intestine4.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7218_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.23 ± 0.93
Basal Forebrain1.45 ± 0.35
Basal Part of Pons1.51 ± 0.63
Cerebellar Cortex1.78 ± 0.72
Cerebellar Nuclei2.14 ± 0.61
Claustrum2.43 ± 0.94
Epithalamus1.47 ± 0.71
Frontal Lobe1.9 ± 0.75
Globus Pallidus2.41 ± 0.75
Hypothalamus1.71 ± 0.54
Insula1.26 ± 0.43
Limbic Lobe2.03 ± 0.73
Mesencephalon2.03 ± 0.82
Myelencephalon1.97 ± 0.75
Occipital Lobe1.8 ± 0.7
Parietal Lobe1.76 ± 0.74
Pontine Tegmentum1.78 ± 0.7
Striatum2 ± 0.84
Subthalamus1.9 ± 0.88
Temporal Lobe1.81 ± 0.73
Thalamus1.85 ± 0.63
White Matter2.65 ± 0.7
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
St7CBCerebellum27.16
44.39
St7CTXCerebral cortex56.86
40.52
St7HIPHippocampal region67.61
100
St7HPFHippocampal formation62.72
76.85
St7HYHypothalamus47.55
34.54
St7LSXLateral septal complex40.18
27.7
St7MBMidbrain29.45
24.69
St7MYMedulla39.08
37.51
St7OLFOlfactory bulb71.97
58.55
St7PPons35.24
31.52
St7PALPallidum45.79
38.57
St7RHPRetrohippocampal region54.27
41.91
St7sAMYStriatum-like amygdalar nuclei50.19
35.76
St7STRStriatum36.44
25.89
St7STRdStriatum dorsal region31.91
23.6
St7STRvStriatum ventral region43.92
28.02
St7THThalamus51.15
42.53
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018