AutismKB 2.0

Annotation Detail for CSPP1


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Basic Information Top
Gene Symbol:CSPP1 ( CSPP,FLJ22490,FLJ38886 )
Gene Full Name: centrosome and spindle pole associated protein 1
Band: 8q13.1-q13.2
Quick LinksEntrez ID:79848; OMIM: 611654; Uniprot ID:CSPP1_HUMAN; ENSEMBL ID: ENSG00000104218; HGNC ID: 26193
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst4 / 6231964
fetus24 / 56401242
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal95 / 336030728
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow4 / 4880181
brain12 / 110098910
cervix1 / 4817120
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine2 / 2344728
kidney6 / 21177728
larynx1 / 2414541
liver6 / 20774328
lung14 / 33697441
lymph0 / 442700 
lymph node4 / 9161043
mammary gland12 / 15327178
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate3 / 18934515
salivary gland0 / 201550 
skin2 / 2105749
spleen4 / 5395274
stomach3 / 9661931
testis13 / 33044239
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221925_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.8
Adipocyte7.05
AdrenalCortex9.2
Adrenalgland6.75
Amygdala7.45
Appendix9
AtrioventricularNode8.3
BDCA4+_DentriticCells7.75
Bonemarrow7.7
BronchialEpithelialCells6.95
CD105+_Endothelial8.65
CD14+_Monocytes7.8
CD19+_BCells(neg._sel.)7.45
CD33+_Myeloid9.6
CD34+8.95
CD4+_Tcells9.85
CD56+_NKCells8
CD71+_EarlyErythroid7.3
CD8+_Tcells6.85
CardiacMyocytes13.5
Caudatenucleus6.75
Cerebellum6.2
CerebellumPeduncles9.15
CiliaryGanglion6.7
CingulateCortex7.95
Colorectaladenocarcinoma7.65
DorsalRootGanglion6.9
FetalThyroid7.45
Fetalbrain8.4
Fetalliver6.5
Fetallung5.95
GlobusPallidus7.2
Heart12.65
Hypothalamus8
Kidney6.7
Leukemia_chronicMyelogenousK-5626.6
Leukemia_promyelocytic-HL-607.05
Leukemialymphoblastic(MOLT-4)5.85
Liver11.2
Lung7.85
Lymphnode6
Lymphoma_burkitts(Daudi)10.4
Lymphoma_burkitts(Raji)11.8
MedullaOblongata6.35
OccipitalLobe6.55
OlfactoryBulb5.85
Ovary5.65
Pancreas6.25
PancreaticIslet8.15
ParietalLobe9.2
Pituitary8.5
Placenta7.35
Pons7.5
PrefrontalCortex8.9
Prostate8
Salivarygland6.5
SkeletalMuscle10.95
Skin6.9
SmoothMuscle8.2
Spinalcord8.15
SubthalamicNucleus8.15
SuperiorCervicalGanglion11.35
TemporalLobe9.7
Testis6.3
TestisGermCell11
TestisIntersitial12.35
TestisLeydigCell8.8
TestisSeminiferousTubule13.95
Thalamus7.7
Thymus5.55
Thyroid8.55
Tongue8.85
Tonsil7.6
Trachea6.25
TrigeminalGanglion9.4
Uterus5.85
UterusCorpus7.2
WholeBlood7.5
Wholebrain5.7
colon7.35
pineal_day9.04
pineal_night8.94
retina10.325
small_intestine7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P32411
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.54 ± 0.39
Basal Forebrain6.51 ± 0.21
Basal Part of Pons6.46 ± 0.42
Cerebellar Cortex6.73 ± 0.3
Cerebellar Nuclei6.06 ± 0.86
Claustrum6.33 ± 0.51
Epithalamus7.15 ± 0.53
Frontal Lobe6.23 ± 0.44
Globus Pallidus6.4 ± 0.34
Hypothalamus5.99 ± 0.2
Insula6.41 ± 0.34
Limbic Lobe6.5 ± 0.34
Mesencephalon6.3 ± 0.4
Myelencephalon6.31 ± 0.45
Occipital Lobe6.54 ± 0.35
Parietal Lobe6.42 ± 0.36
Pontine Tegmentum6.3 ± 0.45
Striatum6.18 ± 0.44
Subthalamus6.26 ± 0.22
Temporal Lobe6.35 ± 0.38
Thalamus6.28 ± 0.27
White Matter6.96 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cspp1CBCerebellum9.12
8.19
Cspp1CTXCerebral cortex16.44
10.83
Cspp1HIPHippocampal region11.09
9.98
Cspp1HPFHippocampal formation9.97
8.3
Cspp1HYHypothalamus6.37
4.48
Cspp1LSXLateral septal complex9.62
6.38
Cspp1MBMidbrain6.04
5.29
Cspp1MYMedulla13.23
13.1
Cspp1OLFOlfactory bulb25.14
17.5
Cspp1PPons8.27
7.62
Cspp1PALPallidum6.2
4.63
Cspp1RHPRetrohippocampal region8.08
5.9
Cspp1sAMYStriatum-like amygdalar nuclei4.58
2.85
Cspp1STRStriatum4.71
3.28
Cspp1STRdStriatum dorsal region2.88
2.19
Cspp1STRvStriatum ventral region8.63
5.35
Cspp1THThalamus9.8
6.77
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CSPP1_HUMAN_0 0 0 0 QQELYKNFLRFQIEEK PRIDE
CSPP1_HUMAN_730 16 730 745 QQELYKNFLRFQIEEK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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