AutismKB 2.0

Annotation Detail for EPHX3


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Basic Information Top
Gene Symbol:EPHX3 ( ABHD9,FLJ22408,MGC131519 )
Gene Full Name: epoxide hydrolase 3
Band: 19p13.12
Quick LinksEntrez ID:79852; OMIM: NA; Uniprot ID:EPHX3_HUMAN; ENSEMBL ID: ENSG00000105131; HGNC ID: 23760
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal20 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus1 / 2020949
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220013_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.75
Adipocyte3.7
AdrenalCortex3.9
Adrenalgland3.1
Amygdala3.95
Appendix3.75
AtrioventricularNode2.85
BDCA4+_DentriticCells4.2
Bonemarrow3.75
BronchialEpithelialCells3.7
CD105+_Endothelial3.75
CD14+_Monocytes4
CD19+_BCells(neg._sel.)4
CD33+_Myeloid4.8
CD34+4.75
CD4+_Tcells4.1
CD56+_NKCells4.55
CD71+_EarlyErythroid3.5
CD8+_Tcells3.7
CardiacMyocytes4.85
Caudatenucleus3.3
Cerebellum3
CerebellumPeduncles4.2
CiliaryGanglion2.7
CingulateCortex3.8
Colorectaladenocarcinoma3.75
DorsalRootGanglion2.75
FetalThyroid3.6
Fetalbrain3.75
Fetalliver3.2
Fetallung3.1
GlobusPallidus2.7
Heart4.8
Hypothalamus4.05
Kidney3.05
Leukemia_chronicMyelogenousK-5623.35
Leukemia_promyelocytic-HL-603.3
Leukemialymphoblastic(MOLT-4)3
Liver4.95
Lung4.15
Lymphnode3.25
Lymphoma_burkitts(Daudi)4.7
Lymphoma_burkitts(Raji)5.25
MedullaOblongata3.4
OccipitalLobe3.35
OlfactoryBulb2.95
Ovary2.45
Pancreas3
PancreaticIslet4
ParietalLobe3.9
Pituitary4.35
Placenta3.85
Pons3.5
PrefrontalCortex4.7
Prostate4.4
Salivarygland2.95
SkeletalMuscle4.55
Skin3.05
SmoothMuscle4.25
Spinalcord4
SubthalamicNucleus3.35
SuperiorCervicalGanglion4.15
TemporalLobe3.4
Testis3.25
TestisGermCell3.15
TestisIntersitial3.1
TestisLeydigCell3.65
TestisSeminiferousTubule3.2
Thalamus3.75
Thymus3
Thyroid4.7
Tongue3.8
Tonsil3.95
Trachea3.1
TrigeminalGanglion3.7
Uterus3.05
UterusCorpus3.3
WholeBlood4.1
Wholebrain3.15
colon3.75
pineal_day4.72
pineal_night4.6
retina4.575
small_intestine3.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P119593
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.31 ± 0.5
Basal Forebrain9 ± 0.21
Basal Part of Pons9.31 ± 0.24
Cerebellar Cortex8.79 ± 0.31
Cerebellar Nuclei9.28 ± 0.27
Claustrum9.52 ± 0.53
Epithalamus8.4 ± 0.39
Frontal Lobe9.13 ± 0.49
Globus Pallidus9.36 ± 0.34
Hypothalamus8.82 ± 0.47
Insula8.99 ± 0.43
Limbic Lobe9.31 ± 0.44
Mesencephalon9.1 ± 0.34
Myelencephalon9.14 ± 0.46
Occipital Lobe9.16 ± 0.47
Parietal Lobe9.1 ± 0.4
Pontine Tegmentum8.96 ± 0.41
Striatum9.46 ± 0.41
Subthalamus9.11 ± 0.07
Temporal Lobe9.05 ± 0.44
Thalamus9.13 ± 0.35
White Matter9.1 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Abhd9CBCerebellum0.67
1.06
Abhd9CTXCerebral cortex0.16
0.21
Abhd9HIPHippocampal region0.21
0.21
Abhd9HPFHippocampal formation0.2
0.24
Abhd9HYHypothalamus0.05
0.09
Abhd9LSXLateral septal complex0
0
Abhd9MBMidbrain0.24
0.49
Abhd9MYMedulla2.17
3.11
Abhd9OLFOlfactory bulb0.46
0.69
Abhd9PPons0.11
0.13
Abhd9PALPallidum0.03
0.1
Abhd9RHPRetrohippocampal region0.18
0.23
Abhd9sAMYStriatum-like amygdalar nuclei0.05
0.02
Abhd9STRStriatum0.13
0.2
Abhd9STRdStriatum dorsal region0.16
0.26
Abhd9STRvStriatum ventral region0.14
0.2
Abhd9THThalamus0.08
0.1
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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