AutismKB 2.0

Annotation Detail for SNX22


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Basic Information Top
Gene Symbol:SNX22 ( FLJ13952 )
Gene Full Name: sorting nexin 22
Band: 15q22.31
Quick LinksEntrez ID:79856; OMIM: NA; Uniprot ID:SNX22_HUMAN; ENSEMBL ID: ENSG00000157734; HGNC ID: 16315
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult319 / 1939121164
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor20 / 114246175
esophageal tumor1 / 1729057
gastrointestinal tumor7 / 11936958
germ cell tumor12 / 26384545
glioma12 / 106883112
head and neck tumor24 / 136302176
kidney tumor1 / 6895914
leukemia13 / 95842135
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma4 / 7175555
non-neoplasia6 / 9725061
normal237 / 336030770
ovarian tumor15 / 76682195
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer14 / 102680136
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites5 / 40015124
bladder10 / 29757336
blood12 / 12347897
bone0 / 716550 
bone marrow0 / 488010 
brain32 / 110098929
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye2 / 2110549
heart2 / 8962622
intestine151 / 234472644
kidney1 / 2117774
larynx10 / 24145414
liver1 / 2077434
lung12 / 33697435
lymph2 / 4427045
lymph node6 / 9161065
mammary gland11 / 15327171
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary16 / 102051156
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta21 / 28082574
prostate20 / 189345105
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach2 / 9661920
testis3 / 3304429
thymus0 / 811310 
thyroid30 / 47473631
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1749_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.45 ± 0.52
Basal Forebrain4.8 ± 0.36
Basal Part of Pons4.96 ± 0.57
Cerebellar Cortex4.31 ± 0.39
Cerebellar Nuclei5.35 ± 0.42
Claustrum4.48 ± 0.6
Epithalamus3.73 ± 0.99
Frontal Lobe4.69 ± 0.59
Globus Pallidus6.06 ± 0.21
Hypothalamus4.21 ± 0.56
Insula4.54 ± 0.96
Limbic Lobe4.49 ± 0.59
Mesencephalon4.74 ± 0.64
Myelencephalon4.72 ± 0.61
Occipital Lobe4.61 ± 0.51
Parietal Lobe4.59 ± 0.51
Pontine Tegmentum4.61 ± 0.53
Striatum5.12 ± 0.57
Subthalamus4.74 ± 0.34
Temporal Lobe4.46 ± 0.46
Thalamus5.02 ± 0.39
White Matter6.63 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Snx22CBCerebellum3.86
4.26
Snx22CTXCerebral cortex0.8
0.86
Snx22HIPHippocampal region0.63
0.49
Snx22HPFHippocampal formation0.57
0.5
Snx22HYHypothalamus0.86
0.56
Snx22LSXLateral septal complex0.69
0.61
Snx22MBMidbrain1.31
1.04
Snx22MYMedulla2.32
1.96
Snx22OLFOlfactory bulb1.04
1.05
Snx22PPons1.3
0.94
Snx22PALPallidum0.79
0.5
Snx22RHPRetrohippocampal region0.44
0.58
Snx22sAMYStriatum-like amygdalar nuclei0.27
0.12
Snx22STRStriatum0.28
0.23
Snx22STRdStriatum dorsal region0.23
0.16
Snx22STRvStriatum ventral region0.24
0.27
Snx22THThalamus1.8
1.11
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018