AutismKB 2.0

Annotation Detail for CPSF7


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Basic Information Top
Gene Symbol:CPSF7 ( FLJ12529,FLJ39024,MGC9315 )
Gene Full Name: cleavage and polyadenylation specific factor 7, 59kDa
Band: 11q12.2
Quick LinksEntrez ID:79869; OMIM: NA; Uniprot ID:CPSF7_HUMAN; ENSEMBL ID: ENSG00000149532; HGNC ID: 30098
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult20 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal20 / 33603075
ovarian tumor1 / 7668213
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine5 / 23447221
kidney0 / 2117770 
larynx1 / 2414541
liver2 / 2077439
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217866_at
Cell line Expression level Expression bar
721_B_lymphoblasts179.45
Adipocyte64.95
AdrenalCortex101.15
Adrenalgland119.95
Amygdala235.2
Appendix61.75
AtrioventricularNode39.45
BDCA4+_DentriticCells156.15
Bonemarrow112.95
BronchialEpithelialCells74.8
CD105+_Endothelial111.1
CD14+_Monocytes145.75
CD19+_BCells(neg._sel.)205.9
CD33+_Myeloid154.8
CD34+685.55
CD4+_Tcells179.3
CD56+_NKCells153.55
CD71+_EarlyErythroid55.25
CD8+_Tcells225.8
CardiacMyocytes66.2
Caudatenucleus124.6
Cerebellum121.05
CerebellumPeduncles116.55
CiliaryGanglion48.65
CingulateCortex91.45
Colorectaladenocarcinoma109.2
DorsalRootGanglion54.95
FetalThyroid80.85
Fetalbrain145.85
Fetalliver105.95
Fetallung106.2
GlobusPallidus48.45
Heart85.4
Hypothalamus110.1
Kidney79.7
Leukemia_chronicMyelogenousK-562103.05
Leukemia_promyelocytic-HL-60100.8
Leukemialymphoblastic(MOLT-4)200.7
Liver113.85
Lung107.2
Lymphnode142.25
Lymphoma_burkitts(Daudi)211.3
Lymphoma_burkitts(Raji)137.55
MedullaOblongata91.75
OccipitalLobe104.1
OlfactoryBulb80.35
Ovary52.65
Pancreas53.35
PancreaticIslet90.85
ParietalLobe120.15
Pituitary190.3
Placenta118.25
Pons83.05
PrefrontalCortex237.55
Prostate117.1
Salivarygland77.75
SkeletalMuscle148.35
Skin55.3
SmoothMuscle66.65
Spinalcord124.1
SubthalamicNucleus70.2
SuperiorCervicalGanglion72.35
TemporalLobe64.9
Testis177.8
TestisGermCell105.8
TestisIntersitial64.9
TestisLeydigCell87.15
TestisSeminiferousTubule94
Thalamus90.25
Thymus195.95
Thyroid182.7
Tongue84.95
Tonsil102.6
Trachea105.15
TrigeminalGanglion50.2
Uterus112.05
UterusCorpus86.9
WholeBlood228
Wholebrain152.5
colon112.35
pineal_day252.66
pineal_night269.96
retina152.65
small_intestine143.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P116376
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.68 ± 0.45
Basal Forebrain7.57 ± 0.26
Basal Part of Pons7.12 ± 0.29
Cerebellar Cortex7 ± 0.24
Cerebellar Nuclei7.18 ± 0.27
Claustrum7.72 ± 0.44
Epithalamus7.27 ± 0.27
Frontal Lobe7.1 ± 0.37
Globus Pallidus7.82 ± 0.18
Hypothalamus7.26 ± 0.31
Insula7.1 ± 0.41
Limbic Lobe7.45 ± 0.48
Mesencephalon7.47 ± 0.42
Myelencephalon7.38 ± 0.44
Occipital Lobe7.71 ± 0.44
Parietal Lobe7.37 ± 0.45
Pontine Tegmentum7.28 ± 0.37
Striatum7.92 ± 0.55
Subthalamus6.97 ± 0.02
Temporal Lobe7.24 ± 0.38
Thalamus7.3 ± 0.29
White Matter8.18 ± 0.6
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
5730453I16RikCBCerebellum77.63
100
5730453I16RikCTXCerebral cortex100
85.82
5730453I16RikHIPHippocampal region87.24
100
5730453I16RikHPFHippocampal formation91.73
100
5730453I16RikHYHypothalamus79.35
68.19
5730453I16RikLSXLateral septal complex90.99
72.87
5730453I16RikMBMidbrain65.97
60.34
5730453I16RikMYMedulla37.79
41.26
5730453I16RikOLFOlfactory bulb88.63
89.41
5730453I16RikPPons38.33
39.28
5730453I16RikPALPallidum66.7
60.12
5730453I16RikRHPRetrohippocampal region98.7
93.08
5730453I16RiksAMYStriatum-like amygdalar nuclei84.51
69.72
5730453I16RikSTRStriatum79.48
62.23
5730453I16RikSTRdStriatum dorsal region72.3
55.53
5730453I16RikSTRvStriatum ventral region98.5
76.28
5730453I16RikTHThalamus72.67
63.83
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CPSF7_HUMAN_163 11 163 173 QNLSQFEAQAR PRIDE
PAp00008428 16 434 449 VLISSLKDCLHGIEAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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