AutismKB 2.0

Annotation Detail for THSD4


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Basic Information Top
Gene Symbol:THSD4 ( ADAMTSL6,FLJ13710,FVSY9334,PRO34005 )
Gene Full Name: thrombospondin, type I, domain containing 4
Band: 15q23
Quick LinksEntrez ID:79875; OMIM: NA; Uniprot ID:THSD4_HUMAN; ENSEMBL ID: ENSG00000187720; HGNC ID: 25835
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult91 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor5 / 13630236
kidney tumor5 / 6895972
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal93 / 336030727
ovarian tumor7 / 7668291
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain14 / 110098912
cervix4 / 4817183
connective tissue2 / 14925513
ear1 / 1621261
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye8 / 21105437
heart3 / 8962633
intestine12 / 23447251
kidney9 / 21177742
larynx2 / 2414582
liver1 / 2077434
lung5 / 33697414
lymph0 / 442700 
lymph node1 / 9161010
mammary gland14 / 15327191
mouth2 / 6705229
muscle2 / 10771518
nerve2 / 15768126
ovary9 / 10205188
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate18 / 18934595
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach4 / 9661941
testis2 / 3304426
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea13 / 52413248
umbilical cord0 / 136800 
uterus21 / 23287890
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219153_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.5
Adipocyte4.35
AdrenalCortex4.55
Adrenalgland3.8
Amygdala4.65
Appendix4.4
AtrioventricularNode3.45
BDCA4+_DentriticCells4.75
Bonemarrow4.4
BronchialEpithelialCells4.4
CD105+_Endothelial4.4
CD14+_Monocytes4.7
CD19+_BCells(neg._sel.)4.7
CD33+_Myeloid5.7
CD34+5.6
CD4+_Tcells4.8
CD56+_NKCells5.25
CD71+_EarlyErythroid4.1
CD8+_Tcells4.2
CardiacMyocytes6.1
Caudatenucleus3.95
Cerebellum3.55
CerebellumPeduncles5
CiliaryGanglion3.3
CingulateCortex4.45
Colorectaladenocarcinoma4.45
DorsalRootGanglion3.4
FetalThyroid4.25
Fetalbrain4.4
Fetalliver3.85
Fetallung3.65
GlobusPallidus3.2
Heart5.95
Hypothalamus4.8
Kidney3.7
Leukemia_chronicMyelogenousK-5623.95
Leukemia_promyelocytic-HL-603.85
Leukemialymphoblastic(MOLT-4)3.55
Liver5.9
Lung4.8
Lymphnode3.8
Lymphoma_burkitts(Daudi)5.6
Lymphoma_burkitts(Raji)6.3
MedullaOblongata4
OccipitalLobe3.95
OlfactoryBulb3.45
Ovary2.9
Pancreas3.5
PancreaticIslet4.7
ParietalLobe4.7
Pituitary5.1
Placenta4.95
Pons4.2
PrefrontalCortex5.5
Prostate5.15
Salivarygland3.5
SkeletalMuscle5.15
Skin3.55
SmoothMuscle5
Spinalcord4.7
SubthalamicNucleus4
SuperiorCervicalGanglion5
TemporalLobe4
Testis3.8
TestisGermCell3.7
TestisIntersitial3.7
TestisLeydigCell4.35
TestisSeminiferousTubule3.75
Thalamus4.45
Thymus3.5
Thyroid5.55
Tongue4.4
Tonsil4.25
Trachea3.7
TrigeminalGanglion4.55
Uterus3.6
UterusCorpus4
WholeBlood4.85
Wholebrain3.8
colon4.4
pineal_day5.48
pineal_night5.36
retina5.35
small_intestine4.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P148249
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.21 ± 0.59
Basal Forebrain5.24 ± 0.26
Basal Part of Pons4.62 ± 0.5
Cerebellar Cortex5.1 ± 0.42
Cerebellar Nuclei6.03 ± 0.58
Claustrum4.97 ± 0.71
Epithalamus5.08 ± 0.66
Frontal Lobe5.52 ± 0.56
Globus Pallidus6.97 ± 0.56
Hypothalamus5.32 ± 0.42
Insula5.25 ± 0.73
Limbic Lobe5.9 ± 0.95
Mesencephalon5.66 ± 0.71
Myelencephalon5.87 ± 0.79
Occipital Lobe6.86 ± 1.08
Parietal Lobe5.83 ± 0.61
Pontine Tegmentum6.03 ± 0.79
Striatum7.41 ± 0.64
Subthalamus5.45 ± 0.11
Temporal Lobe5.45 ± 0.65
Thalamus6.86 ± 0.77
White Matter6.1 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Thsd4CBCerebellum2.02
3.52
Thsd4CTXCerebral cortex1.05
1.06
Thsd4HIPHippocampal region10.48
12.48
Thsd4HPFHippocampal formation6.81
7.44
Thsd4HYHypothalamus0.31
0.28
Thsd4LSXLateral septal complex3.76
2.41
Thsd4MBMidbrain0.91
1.16
Thsd4MYMedulla2.47
2.39
Thsd4OLFOlfactory bulb2.3
2.54
Thsd4PPons1.68
1.59
Thsd4PALPallidum0.31
0.24
Thsd4RHPRetrohippocampal region1.13
0.96
Thsd4sAMYStriatum-like amygdalar nuclei0.14
0.1
Thsd4STRStriatum0.39
0.27
Thsd4STRdStriatum dorsal region0.18
0.15
Thsd4STRvStriatum ventral region0.12
0.08
Thsd4THThalamus2.9
2.67
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp01368293 24 209 232 HGYSSPAHQVPQHGPLYQSDSGPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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