AutismKB 2.0

Annotation Detail for GGNBP2


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Basic Information Top
Gene Symbol:GGNBP2 ( DIF-3,DIF3,FLJ21230,FLJ22561,FLJ42090,LCRG1,LZK1,ZFP403,ZNF403 )
Gene Full Name: gametogenetin binding protein 2
Band: 17q12
Quick LinksEntrez ID:79893; OMIM: 612275; Uniprot ID:GGNB2_HUMAN; ENSEMBL ID: ENSG00000005955; HGNC ID: 19357
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus42 / 56401274
neonate0 / 310970 
infant2 / 2362084
juvenile4 / 5555671
adult117 / 193912160
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor7 / 9417874
cervical tumor3 / 3436687
chondrosarcoma10 / 82823120
colorectal tumor9 / 11424678
esophageal tumor3 / 17290173
gastrointestinal tumor3 / 11936925
germ cell tumor11 / 26384541
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor8 / 9635983
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia12 / 97250123
normal211 / 336030762
ovarian tumor12 / 76682156
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder9 / 29757302
blood4 / 12347832
bone10 / 71655139
bone marrow0 / 488010 
brain54 / 110098949
cervix6 / 48171124
connective tissue11 / 14925573
ear4 / 16212246
embryonic tissue5 / 21572223
esophagus3 / 20209148
eye15 / 21105471
heart6 / 8962666
intestine17 / 23447272
kidney6 / 21177728
larynx3 / 24145124
liver12 / 20774357
lung26 / 33697477
lymph1 / 4427022
lymph node15 / 91610163
mammary gland14 / 15327191
mouth3 / 6705244
muscle4 / 10771537
nerve3 / 15768190
ovary14 / 102051137
pancreas12 / 21481255
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta8 / 28082528
prostate11 / 18934558
salivary gland1 / 2015549
skin4 / 21057418
spleen1 / 5395218
stomach4 / 9661941
testis33 / 33044299
thymus6 / 8113173
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus8 / 23287834
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218079_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts54.7
Adipocyte13.05
AdrenalCortex6.7
Adrenalgland5.85
Amygdala73.3
Appendix18.1
AtrioventricularNode4.7
BDCA4+_DentriticCells97.1
Bonemarrow6.75
BronchialEpithelialCells23.45
CD105+_Endothelial73.65
CD14+_Monocytes68.55
CD19+_BCells(neg._sel.)105
CD33+_Myeloid74.1
CD34+80
CD4+_Tcells127.25
CD56+_NKCells88.05
CD71+_EarlyErythroid50.65
CD8+_Tcells133.3
CardiacMyocytes16.65
Caudatenucleus16.7
Cerebellum8.05
CerebellumPeduncles8.4
CiliaryGanglion4.25
CingulateCortex13.95
Colorectaladenocarcinoma19.7
DorsalRootGanglion5.05
FetalThyroid15.05
Fetalbrain30.7
Fetalliver17.7
Fetallung30.35
GlobusPallidus9.8
Heart4.85
Hypothalamus37.55
Kidney4.45
Leukemia_chronicMyelogenousK-56246.4
Leukemia_promyelocytic-HL-6021.1
Leukemialymphoblastic(MOLT-4)58.15
Liver6.05
Lung5
Lymphnode32
Lymphoma_burkitts(Daudi)46.05
Lymphoma_burkitts(Raji)31.8
MedullaOblongata18.1
OccipitalLobe18.6
OlfactoryBulb14.5
Ovary6
Pancreas21.5
PancreaticIslet15.1
ParietalLobe11.6
Pituitary32.9
Placenta9.7
Pons12.65
PrefrontalCortex82.15
Prostate17
Salivarygland19.85
SkeletalMuscle6.45
Skin8.65
SmoothMuscle21
Spinalcord19.45
SubthalamicNucleus18.45
SuperiorCervicalGanglion19.75
TemporalLobe12.75
Testis21.7
TestisGermCell56.3
TestisIntersitial32.8
TestisLeydigCell22.4
TestisSeminiferousTubule26.5
Thalamus22.6
Thymus13.25
Thyroid43
Tongue8.9
Tonsil8.4
Trachea9.4
TrigeminalGanglion6.75
Uterus25.65
UterusCorpus8.75
WholeBlood55.35
Wholebrain14.3
colon19.75
pineal_day97.14
pineal_night95.52
retina33.35
small_intestine15.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P67892
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.3 ± 0.24
Basal Forebrain8.41 ± 0.14
Basal Part of Pons8.66 ± 0.17
Cerebellar Cortex8.74 ± 0.22
Cerebellar Nuclei8.5 ± 0.32
Claustrum8.43 ± 0.29
Epithalamus8.53 ± 0.23
Frontal Lobe8.66 ± 0.26
Globus Pallidus8.46 ± 0.14
Hypothalamus8.67 ± 0.3
Insula8.63 ± 0.18
Limbic Lobe8.44 ± 0.29
Mesencephalon8.57 ± 0.24
Myelencephalon8.49 ± 0.31
Occipital Lobe8.25 ± 0.36
Parietal Lobe8.53 ± 0.27
Pontine Tegmentum8.48 ± 0.29
Striatum8.25 ± 0.27
Subthalamus8.87 ± 0.33
Temporal Lobe8.56 ± 0.26
Thalamus8.48 ± 0.22
White Matter8.63 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ggnbp2CBCerebellum63.74
92.61
Ggnbp2CTXCerebral cortex100
100
Ggnbp2HIPHippocampal region100
100
Ggnbp2HPFHippocampal formation100
100
Ggnbp2HYHypothalamus98.5
94.29
Ggnbp2LSXLateral septal complex0
0
Ggnbp2MBMidbrain100
100
Ggnbp2MYMedulla97.05
100
Ggnbp2OLFOlfactory bulb100
100
Ggnbp2PPons84.23
100
Ggnbp2PALPallidum90.47
96.04
Ggnbp2RHPRetrohippocampal region100
100
Ggnbp2sAMYStriatum-like amygdalar nuclei100
100
Ggnbp2STRStriatum100
100
Ggnbp2STRdStriatum dorsal region100
100
Ggnbp2STRvStriatum ventral region100
100
Ggnbp2THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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