AutismKB 2.0

Annotation Detail for CYBRD1


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Basic Information Top
Gene Symbol:CYBRD1 ( DCYTB,FLJ23462,FRRS3 )
Gene Full Name: cytochrome b reductase 1
Band: 2q31.1
Quick LinksEntrez ID:79901; OMIM: 605745; Uniprot ID:CYBR1_HUMAN; ENSEMBL ID: ENSG00000071967; HGNC ID: 20797
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus46 / 56401281
neonate3 / 3109796
infant0 / 236200 
juvenile4 / 5555671
adult125 / 193912164
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma2 / 17475114
breast (mammary gland) tumor10 / 94178106
cervical tumor0 / 343660 
chondrosarcoma17 / 82823205
colorectal tumor5 / 11424643
esophageal tumor3 / 17290173
gastrointestinal tumor2 / 11936916
germ cell tumor19 / 26384572
glioma7 / 10688365
head and neck tumor9 / 13630266
kidney tumor6 / 6895987
leukemia4 / 9584241
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia20 / 97250205
normal274 / 336030781
ovarian tumor6 / 7668278
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue11 / 13106839
adrenal gland3 / 3319790
ascites0 / 400150 
bladder2 / 2975767
blood3 / 12347824
bone7 / 7165597
bone marrow2 / 4880140
brain86 / 110098978
cervix0 / 481710 
connective tissue43 / 149255288
ear6 / 16212370
embryonic tissue6 / 21572227
esophagus3 / 20209148
eye17 / 21105480
heart10 / 89626111
intestine15 / 23447263
kidney11 / 21177751
larynx0 / 241450 
liver6 / 20774328
lung23 / 33697468
lymph1 / 4427022
lymph node1 / 9161010
mammary gland11 / 15327171
mouth9 / 67052134
muscle4 / 10771537
nerve5 / 15768317
ovary7 / 10205168
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta11 / 28082539
prostate8 / 18934542
salivary gland1 / 2015549
skin20 / 21057494
spleen0 / 539520 
stomach8 / 9661982
testis33 / 33044299
thymus12 / 81131147
thyroid3 / 4747363
tonsil0 / 169990 
trachea103 / 524131965
umbilical cord1 / 1368073
uterus95 / 232878407
vascular10 / 51780193
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217889_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.35
Adipocyte122.45
AdrenalCortex6.55
Adrenalgland6.25
Amygdala6.25
Appendix6.05
AtrioventricularNode5.2
BDCA4+_DentriticCells6.3
Bonemarrow10.65
BronchialEpithelialCells5.6
CD105+_Endothelial74.05
CD14+_Monocytes6.5
CD19+_BCells(neg._sel.)5.15
CD33+_Myeloid7.6
CD34+9.55
CD4+_Tcells6.15
CD56+_NKCells6.95
CD71+_EarlyErythroid115.15
CD8+_Tcells4.55
CardiacMyocytes10
Caudatenucleus5.2
Cerebellum4.75
CerebellumPeduncles6.6
CiliaryGanglion8.5
CingulateCortex5.55
Colorectaladenocarcinoma10.85
DorsalRootGanglion4.6
FetalThyroid18.95
Fetalbrain5.2
Fetalliver9.8
Fetallung16.25
GlobusPallidus4.25
Heart8.8
Hypothalamus6.35
Kidney4.7
Leukemia_chronicMyelogenousK-5625.3
Leukemia_promyelocytic-HL-604.65
Leukemialymphoblastic(MOLT-4)4.65
Liver8.25
Lung13.3
Lymphnode5.2
Lymphoma_burkitts(Daudi)7.2
Lymphoma_burkitts(Raji)8.05
MedullaOblongata5.25
OccipitalLobe5.2
OlfactoryBulb7.3
Ovary8.2
Pancreas4.5
PancreaticIslet6.15
ParietalLobe6.15
Pituitary8.75
Placenta6.05
Pons5.55
PrefrontalCortex6.35
Prostate6.8
Salivarygland4.75
SkeletalMuscle8.85
Skin4.6
SmoothMuscle80.5
Spinalcord6.2
SubthalamicNucleus5.15
SuperiorCervicalGanglion6.75
TemporalLobe5.25
Testis5
TestisGermCell5.4
TestisIntersitial4.85
TestisLeydigCell5.85
TestisSeminiferousTubule4.75
Thalamus5.45
Thymus4.6
Thyroid44.1
Tongue6.1
Tonsil5.55
Trachea19.05
TrigeminalGanglion5.9
Uterus10.25
UterusCorpus22.5
WholeBlood15.85
Wholebrain5.1
colon7.25
pineal_day6.48
pineal_night6.74
retina14.15
small_intestine91.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P209564
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.52 ± 0.44
Basal Forebrain7.59 ± 0.19
Basal Part of Pons6.54 ± 0.36
Cerebellar Cortex6.75 ± 0.27
Cerebellar Nuclei7.18 ± 0.63
Claustrum6.98 ± 0.52
Epithalamus8.17 ± 0.38
Frontal Lobe7.08 ± 0.46
Globus Pallidus8.63 ± 0.46
Hypothalamus7.49 ± 0.37
Insula7.11 ± 0.28
Limbic Lobe7.03 ± 0.61
Mesencephalon7.59 ± 0.41
Myelencephalon7.42 ± 0.53
Occipital Lobe7.49 ± 0.4
Parietal Lobe7.29 ± 0.52
Pontine Tegmentum7.41 ± 0.36
Striatum8.28 ± 0.38
Subthalamus7.2 ± 0.27
Temporal Lobe7.18 ± 0.38
Thalamus7.56 ± 0.41
White Matter8.02 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cybrd1CBCerebellum0.1
0.34
Cybrd1CTXCerebral cortex0.81
0.93
Cybrd1HIPHippocampal region0.42
0.32
Cybrd1HPFHippocampal formation0.48
0.34
Cybrd1HYHypothalamus0.01
0
Cybrd1LSXLateral septal complex0.38
0.71
Cybrd1MBMidbrain0.18
0.25
Cybrd1MYMedulla0.04
0.06
Cybrd1OLFOlfactory bulb2.46
3.06
Cybrd1PPons0.49
0.69
Cybrd1PALPallidum0.02
0.01
Cybrd1RHPRetrohippocampal region0.59
0.37
Cybrd1sAMYStriatum-like amygdalar nuclei0.13
0.09
Cybrd1STRStriatum0.14
0.14
Cybrd1STRdStriatum dorsal region0.13
0.09
Cybrd1STRvStriatum ventral region0.1
0.09
Cybrd1THThalamus0.03
0.06
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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