AutismKB 2.0

Annotation Detail for NUP85


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Basic Information Top
Gene Symbol:NUP85 ( FLJ12549,Nup75 )
Gene Full Name: nucleoporin 85kDa
Band: 17q25
Quick LinksEntrez ID:79902; OMIM: 170285; Uniprot ID:NUP85_HUMAN; ENSEMBL ID: ENSG00000125450; HGNC ID: 8734
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst9 / 62319144
fetus28 / 56401249
neonate3 / 3109796
infant8 / 23620338
juvenile12 / 55556215
adult145 / 193912174
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor9 / 9417895
cervical tumor4 / 34366116
chondrosarcoma5 / 8282360
colorectal tumor18 / 114246157
esophageal tumor2 / 17290115
gastrointestinal tumor19 / 119369159
germ cell tumor36 / 263845136
glioma9 / 10688384
head and neck tumor6 / 13630244
kidney tumor3 / 6895943
leukemia7 / 9584273
liver tumor14 / 96359145
lung tumor7 / 10312767
lymphoma17 / 71755236
non-neoplasia6 / 9725061
normal231 / 336030768
ovarian tumor3 / 7668239
pancreatic tumor24 / 104616229
primitive neuroectodermal tumor of the CNS33 / 125680262
prostate cancer8 / 10268077
retinoblastoma11 / 46356237
skin tumor6 / 12494948
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites11 / 40015274
bladder1 / 2975733
blood13 / 123478105
bone3 / 7165541
bone marrow3 / 4880161
brain94 / 110098985
cervix4 / 4817183
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus2 / 2020998
eye22 / 211054104
heart6 / 8962666
intestine25 / 234472106
kidney14 / 21177766
larynx1 / 2414541
liver33 / 207743158
lung19 / 33697456
lymph9 / 44270203
lymph node9 / 9161098
mammary gland11 / 15327171
mouth3 / 6705244
muscle11 / 107715102
nerve0 / 157680 
ovary4 / 10205139
pancreas24 / 214812111
parathyroid0 / 205390 
pharynx7 / 41328169
pituitary gland0 / 165850 
placenta27 / 28082596
prostate15 / 18934579
salivary gland0 / 201550 
skin8 / 21057437
spleen3 / 5395255
stomach13 / 96619134
testis35 / 330442105
thymus18 / 81131221
thyroid6 / 47473126
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus18 / 23287877
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218014_at
Cell line Expression level Expression bar
721_B_lymphoblasts156.55
Adipocyte4.75
AdrenalCortex4.7
Adrenalgland3.85
Amygdala4.85
Appendix4.65
AtrioventricularNode3.5
BDCA4+_DentriticCells43.5
Bonemarrow4.6
BronchialEpithelialCells12.6
CD105+_Endothelial52.5
CD14+_Monocytes27.35
CD19+_BCells(neg._sel.)25.8
CD33+_Myeloid34.5
CD34+107.6
CD4+_Tcells45.55
CD56+_NKCells21.2
CD71+_EarlyErythroid36.45
CD8+_Tcells64.5
CardiacMyocytes11.8
Caudatenucleus4.05
Cerebellum4.45
CerebellumPeduncles7.25
CiliaryGanglion3.2
CingulateCortex4.7
Colorectaladenocarcinoma31.9
DorsalRootGanglion3.5
FetalThyroid4.7
Fetalbrain5.15
Fetalliver4.25
Fetallung5.1
GlobusPallidus3.3
Heart10.1
Hypothalamus5.05
Kidney3.7
Leukemia_chronicMyelogenousK-56224.25
Leukemia_promyelocytic-HL-6014.75
Leukemialymphoblastic(MOLT-4)52.2
Liver6.25
Lung5.55
Lymphnode6.75
Lymphoma_burkitts(Daudi)32.15
Lymphoma_burkitts(Raji)6.4
MedullaOblongata4.15
OccipitalLobe4.05
OlfactoryBulb3.75
Ovary3.1
Pancreas3.8
PancreaticIslet5.95
ParietalLobe4.65
Pituitary5.4
Placenta6.65
Pons4.3
PrefrontalCortex5.85
Prostate5.5
Salivarygland3.6
SkeletalMuscle5.3
Skin3.55
SmoothMuscle5.3
Spinalcord4.8
SubthalamicNucleus4.2
SuperiorCervicalGanglion5.25
TemporalLobe4.25
Testis9.45
TestisGermCell9.2
TestisIntersitial5.85
TestisLeydigCell4.8
TestisSeminiferousTubule10.45
Thalamus4.75
Thymus13.45
Thyroid5.8
Tongue4.6
Tonsil5.15
Trachea3.8
TrigeminalGanglion4.6
Uterus4
UterusCorpus4.05
WholeBlood5.5
Wholebrain4
colon4.95
pineal_day5.9
pineal_night5.7
retina6.525
small_intestine7.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5533_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.55 ± 0.85
Basal Forebrain4.41 ± 0.53
Basal Part of Pons5.03 ± 0.58
Cerebellar Cortex5.44 ± 0.4
Cerebellar Nuclei4.71 ± 0.53
Claustrum4.07 ± 0.99
Epithalamus5.24 ± 0.65
Frontal Lobe4.92 ± 0.55
Globus Pallidus4.24 ± 0.31
Hypothalamus4.6 ± 0.89
Insula4.94 ± 0.43
Limbic Lobe4.62 ± 0.67
Mesencephalon4.56 ± 0.65
Myelencephalon4.66 ± 0.65
Occipital Lobe4.15 ± 0.59
Parietal Lobe4.53 ± 0.55
Pontine Tegmentum4.63 ± 0.57
Striatum4.16 ± 0.43
Subthalamus4.9 ± 0.41
Temporal Lobe4.91 ± 0.66
Thalamus4.64 ± 0.63
White Matter5.56 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nup85CBCerebellum6.37
6.69
Nup85CTXCerebral cortex11.03
7.61
Nup85HIPHippocampal region14.5
14.6
Nup85HPFHippocampal formation13.53
12.27
Nup85HYHypothalamus1.84
1.37
Nup85LSXLateral septal complex1.97
1.22
Nup85MBMidbrain4.18
3.62
Nup85MYMedulla6.36
6.55
Nup85OLFOlfactory bulb11.99
8.05
Nup85PPons4.28
4.35
Nup85PALPallidum2.41
1.91
Nup85RHPRetrohippocampal region11.64
9.01
Nup85sAMYStriatum-like amygdalar nuclei5.47
3.88
Nup85STRStriatum2.97
2.51
Nup85STRdStriatum dorsal region2.64
2.66
Nup85STRvStriatum ventral region3.84
2.26
Nup85THThalamus10.32
7.98
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009885 13 219 231 EADASPASAGICR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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