AutismKB 2.0

Annotation Detail for TUSC3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TUSC3 ( D8S1992,M33,MGC13453,MRT7,N33,OST3A )
Gene Full Name: tumor suppressor candidate 3
Band: 8p22
Quick LinksEntrez ID:7991; OMIM: 601385; Uniprot ID:TUSC3_HUMAN; ENSEMBL ID: ENSG00000104723; HGNC ID: 30242
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst5 / 6231980
fetus44 / 56401278
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult164 / 193912184
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma3 / 17475171
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor16 / 26384560
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor5 / 6895972
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor8 / 10312777
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal267 / 336030779
ovarian tumor1 / 7668213
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer1 / 1026809
retinoblastoma5 / 46356107
skin tumor22 / 124949176
soft tissue/muscle tissue tumor27 / 125191215
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder5 / 29757168
blood3 / 12347824
bone6 / 7165583
bone marrow1 / 4880120
brain60 / 110098954
cervix3 / 4817162
connective tissue25 / 149255167
ear7 / 16212431
embryonic tissue19 / 21572288
esophagus0 / 202090 
eye12 / 21105456
heart12 / 89626133
intestine0 / 2344720 
kidney13 / 21177761
larynx0 / 241450 
liver3 / 20774314
lung14 / 33697441
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth2 / 6705229
muscle3 / 10771527
nerve2 / 15768126
ovary4 / 10205139
pancreas31 / 214812144
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta103 / 280825366
prostate6 / 18934531
salivary gland1 / 2015549
skin23 / 210574109
spleen1 / 5395218
stomach0 / 966190 
testis13 / 33044239
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209227_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.65
Adipocyte7.45
AdrenalCortex7
Adrenalgland10.85
Amygdala6.4
Appendix6.75
AtrioventricularNode5.65
BDCA4+_DentriticCells5.55
Bonemarrow6.3
BronchialEpithelialCells5.55
CD105+_Endothelial5.6
CD14+_Monocytes5.85
CD19+_BCells(neg._sel.)5.85
CD33+_Myeloid7
CD34+6.85
CD4+_Tcells6.05
CD56+_NKCells6.4
CD71+_EarlyErythroid5.3
CD8+_Tcells5.05
CardiacMyocytes9
Caudatenucleus7.85
Cerebellum8.55
CerebellumPeduncles9.4
CiliaryGanglion4.9
CingulateCortex6.95
Colorectaladenocarcinoma5.55
DorsalRootGanglion5
FetalThyroid5.75
Fetalbrain8.75
Fetalliver5.2
Fetallung5.5
GlobusPallidus5.45
Heart9.55
Hypothalamus6.8
Kidney5.2
Leukemia_chronicMyelogenousK-5625.4
Leukemia_promyelocytic-HL-605.1
Leukemialymphoblastic(MOLT-4)4.35
Liver10.05
Lung6.15
Lymphnode4.9
Lymphoma_burkitts(Daudi)7.6
Lymphoma_burkitts(Raji)8.6
MedullaOblongata8.9
OccipitalLobe5.4
OlfactoryBulb4.45
Ovary4.95
Pancreas4.85
PancreaticIslet6.4
ParietalLobe6.5
Pituitary24.4
Placenta30.2
Pons5.7
PrefrontalCortex8.7
Prostate6.7
Salivarygland4.9
SkeletalMuscle10.4
Skin5.05
SmoothMuscle8
Spinalcord6.15
SubthalamicNucleus5.5
SuperiorCervicalGanglion8.45
TemporalLobe9.85
Testis5
TestisGermCell4.6
TestisIntersitial4.95
TestisLeydigCell6
TestisSeminiferousTubule4.95
Thalamus6.1
Thymus4.35
Thyroid7
Tongue6.1
Tonsil5.7
Trachea5.5
TrigeminalGanglion6.75
Uterus5.75
UterusCorpus5.8
WholeBlood6
Wholebrain4.95
colon6.1
pineal_day13.22
pineal_night9.24
retina7.075
small_intestine6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P95154
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.31 ± 0.28
Basal Forebrain9.2 ± 0.23
Basal Part of Pons9.32 ± 0.28
Cerebellar Cortex9.31 ± 0.14
Cerebellar Nuclei8.3 ± 0.35
Claustrum9.2 ± 0.24
Epithalamus9.45 ± 0.4
Frontal Lobe9.16 ± 0.35
Globus Pallidus7.76 ± 0.49
Hypothalamus9.62 ± 0.19
Insula9.35 ± 0.27
Limbic Lobe9.26 ± 0.34
Mesencephalon8.9 ± 0.46
Myelencephalon9.03 ± 0.49
Occipital Lobe8.68 ± 0.41
Parietal Lobe8.91 ± 0.32
Pontine Tegmentum9 ± 0.46
Striatum9.4 ± 0.33
Subthalamus9.14 ± 0.17
Temporal Lobe9.19 ± 0.31
Thalamus8.79 ± 0.35
White Matter7.12 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tusc3CBCerebellum15.81
19.6
Tusc3CTXCerebral cortex100
100
Tusc3HIPHippocampal region62.41
100
Tusc3HPFHippocampal formation84.07
100
Tusc3HYHypothalamus50
48.36
Tusc3LSXLateral septal complex72.62
63.43
Tusc3MBMidbrain41.25
37.64
Tusc3MYMedulla16.78
18.06
Tusc3OLFOlfactory bulb83.97
93.08
Tusc3PPons26.03
26.47
Tusc3PALPallidum39.68
41.61
Tusc3RHPRetrohippocampal region100
100
Tusc3sAMYStriatum-like amygdalar nuclei100
100
Tusc3STRStriatum100
100
Tusc3STRdStriatum dorsal region100
100
Tusc3STRvStriatum ventral region93.26
77.38
Tusc3THThalamus30.24
27.69
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp01428104 10 53 62 VEQLMEWSSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved