AutismKB 2.0

Annotation Detail for ACTR5


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Basic Information Top
Gene Symbol:ACTR5 ( Arp5,FLJ12785,INO80M )
Gene Full Name: ARP5 actin-related protein 5 homolog (yeast)
Band: 20q11.23
Quick LinksEntrez ID:79913; OMIM: NA; Uniprot ID:ARP5_HUMAN; ENSEMBL ID: ENSG00000101442; HGNC ID: 14671
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst4 / 6231964
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor9 / 26384534
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia1 / 9725010
normal31 / 33603079
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain20 / 110098918
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine2 / 2344728
kidney2 / 2117779
larynx0 / 241450 
liver6 / 20774328
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary4 / 10205139
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach0 / 966190 
testis12 / 33044236
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219623_at
Cell line Expression level Expression bar
721_B_lymphoblasts35
Adipocyte15.65
AdrenalCortex16.5
Adrenalgland13.15
Amygdala12.25
Appendix15.6
AtrioventricularNode12.3
BDCA4+_DentriticCells46.5
Bonemarrow15.45
BronchialEpithelialCells15.6
CD105+_Endothelial35.25
CD14+_Monocytes20.2
CD19+_BCells(neg._sel.)27
CD33+_Myeloid37.25
CD34+49.65
CD4+_Tcells45.8
CD56+_NKCells45.5
CD71+_EarlyErythroid22.1
CD8+_Tcells58.4
CardiacMyocytes19.55
Caudatenucleus14.2
Cerebellum12.8
CerebellumPeduncles17.8
CiliaryGanglion11.2
CingulateCortex16.65
Colorectaladenocarcinoma25.05
DorsalRootGanglion12.35
FetalThyroid15.4
Fetalbrain15.8
Fetalliver13.85
Fetallung13.1
GlobusPallidus11.65
Heart19.65
Hypothalamus16.75
Kidney12.7
Leukemia_chronicMyelogenousK-56214.25
Leukemia_promyelocytic-HL-6014.2
Leukemialymphoblastic(MOLT-4)15.9
Liver21
Lung17.35
Lymphnode16.05
Lymphoma_burkitts(Daudi)20.2
Lymphoma_burkitts(Raji)26.9
MedullaOblongata14.55
OccipitalLobe13.8
OlfactoryBulb16.4
Ovary10.6
Pancreas12.8
PancreaticIslet16.3
ParietalLobe16.9
Pituitary18.75
Placenta13.6
Pons15.05
PrefrontalCortex19.25
Prostate18.55
Salivarygland12.75
SkeletalMuscle19.35
Skin11.95
SmoothMuscle18.05
Spinalcord17
SubthalamicNucleus14.35
SuperiorCervicalGanglion18.1
TemporalLobe14.55
Testis31.2
TestisGermCell22.15
TestisIntersitial30.55
TestisLeydigCell16.65
TestisSeminiferousTubule18.55
Thalamus15.75
Thymus12.45
Thyroid19.2
Tongue18.1
Tonsil15.55
Trachea13.15
TrigeminalGanglion17.5
Uterus13
UterusCorpus14.2
WholeBlood17.35
Wholebrain13.4
colon15.65
pineal_day20.16
pineal_night24.02
retina21.95
small_intestine14.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11263_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.72 ± 1.1
Basal Forebrain2.08 ± 0.37
Basal Part of Pons1.9 ± 0.46
Cerebellar Cortex2.25 ± 0.7
Cerebellar Nuclei2.46 ± 0.75
Claustrum3.01 ± 1.04
Epithalamus1.94 ± 0.76
Frontal Lobe2.07 ± 0.76
Globus Pallidus2.31 ± 0.87
Hypothalamus2.26 ± 0.49
Insula2.07 ± 0.68
Limbic Lobe2.25 ± 0.63
Mesencephalon2.43 ± 0.75
Myelencephalon2.25 ± 0.67
Occipital Lobe2.2 ± 0.64
Parietal Lobe2.26 ± 0.64
Pontine Tegmentum2.32 ± 0.8
Striatum2.47 ± 0.67
Subthalamus2.61 ± 0.32
Temporal Lobe2.18 ± 0.71
Thalamus2.09 ± 0.71
White Matter2.8 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Actr5CBCerebellum1.16
1.84
Actr5CTXCerebral cortex2.66
1.98
Actr5HIPHippocampal region0.66
0.69
Actr5HPFHippocampal formation0.74
0.76
Actr5HYHypothalamus1.2
1.1
Actr5LSXLateral septal complex0.2
0.27
Actr5MBMidbrain1.1
1.32
Actr5MYMedulla2.74
2.95
Actr5OLFOlfactory bulb8.32
7.3
Actr5PPons2.16
2.32
Actr5PALPallidum1.25
1.06
Actr5RHPRetrohippocampal region0.81
0.84
Actr5sAMYStriatum-like amygdalar nuclei0.36
0.32
Actr5STRStriatum2.09
1.84
Actr5STRdStriatum dorsal region2.23
2.1
Actr5STRvStriatum ventral region3.43
2.5
Actr5THThalamus2.29
1.98
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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