AutismKB 2.0

Annotation Detail for MAGIX


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Basic Information Top
Gene Symbol:MAGIX ( FLJ21687,JM10,MGC138889,PDZX )
Gene Full Name: MAGI family member, X-linked
Band: Xp11.23
Quick LinksEntrez ID:79917; OMIM: NA; Uniprot ID:MAGIX_HUMAN; ENSEMBL ID: ENSG00000017621; HGNC ID: 30006
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult21 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma7 / 10688365
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal28 / 33603078
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain11 / 11009899
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine3 / 23447212
kidney3 / 21177714
larynx0 / 241450 
liver2 / 2077439
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas0 / 2148120 
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta4 / 28082514
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_729_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.25 ± 0.71
Basal Forebrain4.07 ± 0.46
Basal Part of Pons3.67 ± 0.76
Cerebellar Cortex4.1 ± 0.59
Cerebellar Nuclei3.91 ± 0.89
Claustrum3.88 ± 0.58
Epithalamus3.86 ± 0.57
Frontal Lobe3.74 ± 0.66
Globus Pallidus4.61 ± 0.62
Hypothalamus3.71 ± 0.64
Insula3.74 ± 0.78
Limbic Lobe3.94 ± 0.62
Mesencephalon3.98 ± 0.71
Myelencephalon3.97 ± 0.67
Occipital Lobe3.88 ± 0.75
Parietal Lobe3.78 ± 0.66
Pontine Tegmentum3.8 ± 0.72
Striatum3.79 ± 0.71
Subthalamus3.81 ± 0.6
Temporal Lobe3.84 ± 0.67
Thalamus3.8 ± 0.64
White Matter3.74 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PdzxCBCerebellum4.98
6.36
PdzxCTXCerebral cortex5.21
4.62
PdzxHIPHippocampal region1.83
2.25
PdzxHPFHippocampal formation1.91
1.97
PdzxHYHypothalamus0.4
0.41
PdzxLSXLateral septal complex1.18
0.99
PdzxMBMidbrain0.86
1.43
PdzxMYMedulla10.62
14.99
PdzxOLFOlfactory bulb8.79
8.49
PdzxPPons1.55
2.13
PdzxPALPallidum0.75
0.73
PdzxRHPRetrohippocampal region2.11
1.65
PdzxsAMYStriatum-like amygdalar nuclei0.71
0.97
PdzxSTRStriatum0.91
0.78
PdzxSTRdStriatum dorsal region0.3
0.26
PdzxSTRvStriatum ventral region3.22
2.34
PdzxTHThalamus1.22
1.37
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018