AutismKB 2.0

Annotation Detail for TNIP3


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Basic Information Top
Gene Symbol:TNIP3 ( ABIN-3,FLJ21162,LIND )
Gene Full Name: TNFAIP3 interacting protein 3
Band: 4q27
Quick LinksEntrez ID:79931; OMIM: 608019; Uniprot ID:TNIP3_HUMAN; ENSEMBL ID: ENSG00000050730; HGNC ID: 19315
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult10 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal19 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis2 / 3304426
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220655_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.15
Adipocyte7.55
AdrenalCortex12.8
Adrenalgland7.35
Amygdala7.8
Appendix13.65
AtrioventricularNode10.1
BDCA4+_DentriticCells7.4
Bonemarrow9.15
BronchialEpithelialCells7.3
CD105+_Endothelial7.95
CD14+_Monocytes8.65
CD19+_BCells(neg._sel.)8.35
CD33+_Myeloid9.95
CD34+9.7
CD4+_Tcells7.8
CD56+_NKCells8.45
CD71+_EarlyErythroid7.7
CD8+_Tcells7.1
CardiacMyocytes15.75
Caudatenucleus7.05
Cerebellum6.5
CerebellumPeduncles9.8
CiliaryGanglion9.7
CingulateCortex8.8
Colorectaladenocarcinoma8
DorsalRootGanglion7.55
FetalThyroid7.95
Fetalbrain7.6
Fetalliver7.05
Fetallung5.8
GlobusPallidus6.7
Heart13.65
Hypothalamus7.7
Kidney7.45
Leukemia_chronicMyelogenousK-5626.9
Leukemia_promyelocytic-HL-606.85
Leukemialymphoblastic(MOLT-4)5.6
Liver12.6
Lung8.4
Lymphnode6.35
Lymphoma_burkitts(Daudi)10.6
Lymphoma_burkitts(Raji)13.4
MedullaOblongata7
OccipitalLobe7
OlfactoryBulb6
Ovary7.55
Pancreas6.9
PancreaticIslet8.55
ParietalLobe9.4
Pituitary9.05
Placenta7.55
Pons8.3
PrefrontalCortex8.6
Prostate8.65
Salivarygland6.8
SkeletalMuscle17.75
Skin9.1
SmoothMuscle9
Spinalcord7.9
SubthalamicNucleus7.7
SuperiorCervicalGanglion19.6
TemporalLobe7.55
Testis6.6
TestisGermCell6.35
TestisIntersitial7.3
TestisLeydigCell9.25
TestisSeminiferousTubule6.95
Thalamus8.3
Thymus5.75
Thyroid9.1
Tongue12.35
Tonsil9.3
Trachea6.4
TrigeminalGanglion12.65
Uterus6
UterusCorpus9.2
WholeBlood8.25
Wholebrain5.7
colon7.65
pineal_day9.4
pineal_night9.26
retina9.375
small_intestine7.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P386478
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.94 ± 1.11
Basal Forebrain3.14 ± 0.33
Basal Part of Pons4.58 ± 0.35
Cerebellar Cortex3.81 ± 1.01
Cerebellar Nuclei3.65 ± 0.85
Claustrum4.29 ± 0.71
Epithalamus2.99 ± 0.92
Frontal Lobe3.4 ± 0.94
Globus Pallidus2.61 ± 0.45
Hypothalamus3.82 ± 0.52
Insula3.65 ± 0.39
Limbic Lobe3.45 ± 0.99
Mesencephalon3.5 ± 0.94
Myelencephalon3.41 ± 0.9
Occipital Lobe3.4 ± 1.13
Parietal Lobe3.39 ± 0.77
Pontine Tegmentum3.15 ± 0.88
Striatum2.48 ± 0.89
Subthalamus4.33 ± 1.67
Temporal Lobe3.46 ± 0.84
Thalamus3.14 ± 0.78
White Matter2.3 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
9030611K07RikCBCerebellum18.88
27.76
9030611K07RikCTXCerebral cortex1.55
1.42
9030611K07RikHIPHippocampal region2.27
2.79
9030611K07RikHPFHippocampal formation2.03
2.67
9030611K07RikHYHypothalamus2.75
2.07
9030611K07RikLSXLateral septal complex2.06
2.04
9030611K07RikMBMidbrain1.7
2.44
9030611K07RikMYMedulla10.66
10.75
9030611K07RikOLFOlfactory bulb16.07
14.89
9030611K07RikPPons3.76
4.11
9030611K07RikPALPallidum3.1
3.18
9030611K07RikRHPRetrohippocampal region1.53
2.37
9030611K07RiksAMYStriatum-like amygdalar nuclei6.13
4.51
9030611K07RikSTRStriatum1.6
1.58
9030611K07RikSTRdStriatum dorsal region0.67
0.87
9030611K07RikSTRvStriatum ventral region2.24
1.86
9030611K07RikTHThalamus1.71
2.15
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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